The Computational Materials Science Scientist will apply state-of-the-art computational chemistry and crystallographic tools to predict the solid-state and particle properties of Pfizer molecules to streamline experimental efforts and to design better medicines. This will enable Pfizer project teams to de-risk their programs and to move rapidly into clinical studies with the goal of commercialization. The role is highly collaborative, requiring extensive work on multi-disciplinary project teams. With this role there is also a significant opportunity to publish peer reviewed research and to develop novel computational methods, addressing gaps in our current knowledge and capabilities.
Responsibilities
• Apply state-of-the-art physics based computational approaches to predict the properties and performance across range of molecules (R05 and bR05)
• Conduct crystal structure prediction (CSP) calculations and free energy calculations for polymorph stability ranking
• Utilize various physics/informatics (i.e. molecular simulations, density functional theory, H-bonding propensity analysis, full Interaction map) based computational tools for design and derisking of commercial solid form • Develop and apply physics/ML-AI based computational tools to investigate and understand the particle properties, surface and performance
• Participate on multidisciplinary project teams and collaborate with colleagues to define and recommend follow up screening and characterization strategies to complement computational studies according to project timelines.
• Oversee the work of external partners conducting computational analyses and provide tactical guidance and critical analysis of their work
• Solve scientific problems using contemporary solid state computational techniques.
• Lead the development of new scientific approaches and knowledge within the Material Sciences organization. This is an individual contributor role.
Basic Qualifications
• Candidate to have a PhD in Computational Chemistry, Physics, Materials Science or Engineering, or a closely-related discipline; OR a Master’s degree in these disciplines with 5-10 years of relevant experience in industry or academia. This is an individual contributor role.
• Strong coding skills in a scientific programming language (such as C/C++, Python, Perl) with demonstrated evidence of coding expertise and data analysis.
• Competency in UNIX/Linux and HPC environments for submission and monitoring of jobs.
Preferred Qualifications
• Experience with computational chemistry software (GROMACS, Gaussian, GAMESS-US, cp2k, quantum espresso and VASP) and the CCDC tools preferred.
• Knowledgeable of fundamental physical chemistry and materials science concepts such as thermodynamics, solvation, crystallography, symmetry, nucleation and crystal growth — either through coursework or experience.
• Strong analytical and mathematical skills (geometry, algebra, statistics, differential calculus).
Relocation support available
Work Location Assignment:On Premise
The annual base salary for this position ranges from $93,600.00 to $156,000.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site 60 U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available onPfizer Careers.
Research and Development
