Flagship Pioneering

Senior Scientist, Assay Development

Flagship Pioneering$126K — $181K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Chemistry, Biochemistry, Molecular Biology or related field with 5+ years of post-graduate experience (industry preferred)
  • Experience developing immunoassays and protein detection methods
  • Proficiency in assay troubleshooting, validation, and verification
  • Hands-on experience with clinical sample testing, including plasma and serum
  • Strong contributions to experimental design and data analysis
  • Ability to manage multiple projects both independently and collaboratively
  • Excellent written and verbal communication skills for reporting results

Responsibilities

  • Optimize and troubleshoot ultrasensitive immunoassay protocols for EV markers
  • Modify assay reagents to enhance sensitivity and specificity
  • Develop and refine laboratory protocols for FL103's platform
  • Stay updated with scientific literature to maintain technical expertise
  • Coordinate activities with Contract Research Organizations (CROs) and collaborators
  • Effectively communicate experimental results through presentations and reports
  • Mentor and build the experimental team

Benefits

  • Healthcare coverage
  • Annual incentive program
  • Retirement benefits
  • Broad range of other benefits
Full Job Description
Position Summary:

FL103 is seeking a highly motivated and experienced senior scientist to lead the design, development, optimization and validation of extracellular vesicle based in vitro assays to help diagnose health and disease. The successful candidate will be a driven, experienced scientist who is enthusiastic about developing state-of-the-art techniques to pioneer the detection of low abundance biomarkers from minimally invasive biospecimens in a multiplex format. The position will provide a unique opportunity to play a foundational role in the development of FL103's innovative bioplatform.

Responsibilities:
  • Optimize and troubleshoot ultrasensitive immunoassay protocols to detect EV markers
  • Change assay reagents and components to optimize assay performance, driving increases in sensitivity and specificity
  • Develop laboratory protocols and optimize workflows to build the foundation of FL103's platform
  • Maintain scientific and technical expertise through familiarity with scientific literature
  • Coordinate with Contract Research Organizations (CROs) and external collaborators
  • Communicate experimental results effectively through oral presentations and written reports, ensuring clear and concise dissemination of information to the FL103 team
  • Help lead, mentor, and build experimental team

Qualifications:
  • PhD in Chemistry, Biochemistry, Molecular Biology or a related discipline with 5+ years of post-graduate experience (industry preferred)
  • Demonstrated experience developing immunoassays, protein detection methods, molecular diagnostics, etc.
  • Experience in assay troubleshooting, validation and verification
  • Clinical sample testing, including plasma and serum
  • Demonstrated ability to be a thoughtful contributor to experimental design and data analysis
  • Ability to manage multiple projects, working both independently and collaboratively within a dynamic team
  • Excellent written and verbal communication skills to present results and scientific data to the internal team and/or collaborators
  • Enthusiastic about playing a pivotal role in building the foundation of a new biotech company

Preferred Qualifications
  • General experience with extracellular vesicles
  • Experience guiding products from concept through feasibility, validation and launch
  • Experience working under a quality management system
  • Demonstrated experience working with established standards related to development and validation of biomarker assays, including CLSI guidelines or working within a CLIA regulated environment


The salary range for this role is $126,000 - $181,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. FL103 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL103's good faith estimate as of the date of publication and may be modified in the future.

About Flagship Pioneering

Flagship Pioneering is a life sciences innovation enterprise that conceives, creates, resources, and develops first-in-category life sciences companies. The firm operates through its Flagship Labs unit, which is a dedicated innovation foundry that invents and launches transformative companies. Flagship Pioneering has created over 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. The firm's portfolio includes companies in the fields of therapeutics, health technologies, and sustainability. Flagship Pioneering was founded in 2000 and is headquartered in Cambridge, Massachusetts.
Learn more about Flagship Pioneering
Size
500 employees
Industry

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