Summary of Position:
ReCode is seeking a Senior Research Associate to work as part of a team to conduct laboratory experiments to support the development of robust scalable LNP-encapsulated nucleic acids formulations and manufacturing processes, including lab-scale process development, process scaleup, and in-process characterization. You will have the opportunity to work as an integral part of a talented, diverse team of scientists, and develop career in the exciting field of RNA therapeutics. The ideal candidate will be proactive, enthusiastic, and show a passion for LNP-RNA formulation and process development and should have strong communication and collaboration skills, along with a background in LNP formulation and process development.
Responsibilities:
- Executes studies to define formulation components, vehicle, and primary container.
- Operates common biopharmaceutical unit operations such as mixing, dialysis, tangential flow filtration, and sterile filtration.
- Performs in-process characterization such as pH, particle size, encapsulation efficiency measurement etc.
- Conducts troubleshooting and technical investigations as needed.
- Executes experiments to meet agreed upon deliverables and timelines.
- Maintains thorough and detailed electronic lab notebooks and documentation records.
- Supports and participates in R&D and project management meetings.
- Adheres to all laboratory safety requirements and procedures.
- Assists in maintaining general laboratory functionality and lab equipment, including ordering and receiving of lab supplies.
Qualifications:
- B.S. in Chemical Engineering, Chemistry, Bioengineering, Material Sciences, Pharmaceutical Sciences or related scientific discipline with typically 5+ years laboratory experience or M.S. in Chemical Engineering, Chemistry, Bioengineering, Material Sciences, Pharmaceutical Sciences or related scientific discipline with typically 3+ years laboratory experience (ideally in organic chemical synthesis, nanoparticles, formulation development, nucleic acids, drug delivery)
- Hands-on experience with HPLC, UPLC, LC-MS and various analytical techniques is a must. Extensive hands-on experience on the analysis and characterization of lipids is preferred.
- Attention to detail and excellent skills in Microsoft Office and data analysis software (e.g., Empower, ChemStation, Chromeleon, etc.) and other applications.
- Must be comfortable working in a fast-paced, cross-functional environment and collaborate effectively with other team members.
- Strong oral and written communication skills to support internal and external communications/presentations.
Physical Requirements and Work Environment:
- Regularly required to stand, bend, reach, and work at a laboratory bench for extended periods; occasionally required to lift and move materials or equipment up to 25 lbs.
- Regularly exposed to laboratory chemicals, biological materials, and equipment; required to wear personal protective equipment (PPE) and follow all safety protocols.
- Reasonable accommodations will be made to enable individuals with disabilities to perform the essential functions of this role.
Benefits Offered:
- Company pays full premium for employee + family medical, dental, and vision insurance
- Company-sponsored 401(k) plan with employer contribution
- 15 days of company paid holidays, including a week off between Christmas and New Year
- FSA available, including a lifestyle spending account subsidized by company
- Employee stock option grant and annual performance bonus
ReCode Therapeutics (www.recodetx.com) offers a competitive compensation/benefits package with a friendly, collaborative culture that values employee engagement and ongoing career development.
The expected base salary is $110,000 - $130,000, based on experience.
This job description is intended to describe the general nature of the role and is not an exhaustive list of duties, responsibilities, or qualifications; duties may change at ReCode's discretion. Employment with ReCode is at-will.
