**Applicants MUST have authorization to work in the U.S. indefinitely without restriction or sponsorship.** **Job Summary: **The Oligonucleotide Scientist is responsible for developing, optimizing, validating, and executing analytical methods to support oligonucleotide API, drug substance, and drug product testing. The role focuses primarily on HPLC/UHPLC and mass spectrometry (e.g., LC-MS, LC-MS/MS) for identity, purity/impurity profiling, quantitation, and stability-indicating assessments. The scientist will author methods, protocols and reports, ensure data integrity and compliance within GxP environments, and provide technical leadership for routine testing and investigations and mentoring of junior staff. Applies GMP in all areas of responsibility, as appropriate. - Performing a large variety of analytical tasks for the validation of analytical methods used in the testing of drug products and raw materials by means of various procedures including HPLC, GC, UV/Vis, and dissolution. - Reading, understanding, and interpreting diverse analytical procedures. - Conducting analytical investigations. - Troubleshoot instrumentation and communicate with vendors when required. - Train and mentor junior staff in laboratory procedures. - Manage and discuss projects with clients. **Qualifications** **The Ideal Candidate would possess:** - Excellent communication (oral and written) and attention to detail. - Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude - Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies **Minimum Qualifications:** - BS or MS degree in analytical chemistry or other related degree concentration. - BS and 4+ years of industry experience, MS and 2+ years of industry experience, or PhD and 1+ year of industry experience. - **Industry experience with oligonucleotides** and drug product testing - 3-5 years of experience with LC chromatographic validation in a GMP environment. - Authorization to work in the U.S. **without immediate or future sponsorship.** **Additional Information** Working schedule will be **Full-Time, First Shift, Mon-Fri, 8am-4pm. **Candidates currently living within a commutable distance of Lancaster, PA are encouraged to apply. 25% travel may be required. This position is **NOT** remote. **What we Offer:** - Excellent full time benefits including comprehensive medical coverage, dental, and vision options - Life and disability insurance - 401(k) with company match - Paid vacation and holidays