Sanofi

Senior Director, US Rare Disease Value and Access

Sanofi$206K — $297K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree required; advanced degree preferred (MBA, PharmD, PhD, etc.)
  • 10+ years of market access and payer experience in the pharmaceutical/biotech sector
  • 7+ years of leadership experience managing teams and cross-functional initiatives
  • Expertise in pricing, contracting, reimbursement, and formulary management for payer access strategies
  • Proven record in gross-to-net (GTN) management and financial modeling
  • Strong financial acumen with experience in pricing strategy and P&L impact
  • Ability to navigate complex regulatory environments and manage competing priorities

Responsibilities

  • Partner with senior leadership to set pricing, contracting, GTN, and reimbursement strategies
  • Develop evidence-based market access strategies to maximize formulary adoption
  • Create compelling value propositions for payers and key stakeholders
  • Optimize GTN performance across pricing, rebates, and discounts
  • Monitor GTN performance and recommend strategies to protect profitability
  • Lead cross-channel GTN pull-through initiatives
  • Drive payer engagement and market access knowledge through advisory board programs
  • Champion launch readiness for upcoming therapies, including AATD therapy

Benefits

  • Inclusive work environment that values diversity
  • Opportunities for career advancement and development
  • Access to employee benefit programs
  • Support for continuous learning and re-skilling
  • Encouragement of innovative thinking and experimentation
Full Job Description
Job title: Senior Director, US Rare Disease Value and Access

Location: Cambridge, MA

As Senior Director, US Rare Disease Value and Access within our US Rare Disease Leadership Team, you'll own payer-focused access strategy across a $2.2B business with 7 marketed products and 2 pipeline launches, including a landmark AATD therapy in 1H 2027. You'll lead pricing, contracting, reimbursement, and GTN strategy to maximize formulary adoption and patient access. This role is a member of the US Leadership Team and reports directly to the General Manager. Ready to get started?

You'll be joining Sanofi's US Rare Disease business at a pivotal moment-managing market access for a portfolio with clear growth trajectory to $3.1B by 2030, leading payer strategy for breakthrough therapies, and ensuring patients can access innovative treatments without delay.

Main responsibilities:
  • Partner with GM and senior leadership to set direction for pricing, contracting, GTN, and reimbursement across rare disease portfolio
  • Develop evidence-based market access strategies that maximize formulary adoption and patient access
  • Create compelling value propositions for payers, providers, and key stakeholders
  • Oversee and optimize GTN across the therapeutic area-pricing, rebates, and discounts by channel
  • Monitor GTN performance and deliver recommendations to senior leadership to protect profitability
  • Collaborate with Finance, Forecasting, Trade, Legal, and Patient Support Services to improve net sales
  • Lead GTN pull-through across all channels and geographies based on formulary position
  • Anticipate changes in regulatory and reimbursement landscape; ensure sustained compliance and access
  • Develop primary payer research and advisory board programs to close market access knowledge gaps
  • Champion launch readiness for landmark AATD therapy (1H 2027) across payer, access, and reimbursement dimensions
  • Monitor competitive landscape and payer behavior in partnership with Business Insights & Solutions
  • Define KPIs and track progress against access and financial targets
  • Balance brand objectives and patient access priorities when they are in conflict
  • Build, develop, and lead a high-performing team of 2 direct reports


About you

Role Overview:
  • The Senior Director, US Rare Disease Value and Access owns the value, evidence, pricing, and reimbursement strategy that turns an approved rare disease therapy into a covered, affordable, accessible one. The role spans HEOR and evidence generation, pricing and contracting, payer engagement, and policy - working backwards from what payers need to be convinced of value, often with limited trial data. In rare disease, access is not a downstream function: it is a strategic driver that shapes the commercial case from before launch.
  • Beyond access expertise, the Head of Access Strategy must lead the function through the new era of AI-augmented evidence and value work. The six behaviors below apply to the whole leadership team; the ones this role leans on hardest are highlighted.


Leadership Behavior:

What It Means in the New Era

1. Leads with AI-augmented judgment
  • Uses data and AI to decide faster and better - while owning the judgment calls AI cannot make.

2. Orchestrates across boundaries
  • Delivers through influence, shared goals, and trust as functional silos dissolve - not through positional control.

3. Drives change and adoption
  • Pulls the team through AI and digital change, creates psychological safety to experiment, and names resistance rather than tolerating it.

4. Obsesses over the patient outcome
  • Anchors decisions to the patient's find-to-adherence journey, not functional activity metrics; treats advocacy and equity as strategic.

5. Models learning agility
  • Reskills continuously, experiments, and fails fast in the open so the team does the same.

6. Builds talent density
  • Runs lean with an elite bar: a few exceptional people, amplified by AI, outproduce larger teams. Makes the hard talent calls, raises the standard, and develops those they keep.


Qualifications:
  • Bachelor's degree required; advanced degree (MBA, PharmD, MPH, MS, PhD) strongly preferred
  • 10+ years of market access and payer experience, gained within the pharmaceutical/biotech industry or from external environments such as payer organizations, managed care, consulting, or health economics firms
  • 7+ years of leadership experience managing teams and cross-functional initiatives
  • Demonstrated expertise in payer access strategy: pricing, contracting, reimbursement, formulary management
  • Proven track record in GTN management and financial modeling
  • Strong financial acumen including P&L impact and pricing strategy
  • Experience with value proposition development and payer evidence generation
  • Experience in rare disease or specialty therapeutics preferred
  • Excellent communication, negotiation, and executive influence skills
  • Ability to navigate complex, highly regulated environments while managing multiple priorities


Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:
$206,250.00 - $297,916.66

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.

About Sanofi

Sanofi is a global pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs and vaccines. The company operates in over 170 countries and has a diverse portfolio of products that includes treatments for diabetes, cancer, cardiovascular disease, and rare diseases. Sanofi is committed to improving global health and has a strong focus on innovation and sustainability. The company has received numerous awards for its research and development efforts and is recognized as a leader in the pharmaceutical industry.
Learn more about Sanofi
Market Cap
$121.6 billion
Industry
Net Income
$12.3 billion
Founded
1990
5 Year Trend
+2.5%
Revenue
$37.3 billion
NASDAQ

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