Job title: Senior Director, US Rare Disease Value and Access
Location: Cambridge, MA
About the jobAs Senior Director, US Rare Disease Value and Access within our US Rare Disease Leadership Team, you'll own payer-focused access strategy across a $2.2B business with 7 marketed products and 2 pipeline launches, including a landmark AATD therapy in 1H 2027. You'll lead pricing, contracting, reimbursement, and GTN strategy to maximize formulary adoption and patient access. This role is a member of the US Leadership Team and reports directly to the General Manager. Ready to get started?
You'll be joining Sanofi's US Rare Disease business at a pivotal moment-managing market access for a portfolio with clear growth trajectory to $3.1B by 2030, leading payer strategy for breakthrough therapies, and ensuring patients can access innovative treatments without delay.
Main responsibilities:- Partner with GM and senior leadership to set direction for pricing, contracting, GTN, and reimbursement across rare disease portfolio
- Develop evidence-based market access strategies that maximize formulary adoption and patient access
- Create compelling value propositions for payers, providers, and key stakeholders
- Oversee and optimize GTN across the therapeutic area-pricing, rebates, and discounts by channel
- Monitor GTN performance and deliver recommendations to senior leadership to protect profitability
- Collaborate with Finance, Forecasting, Trade, Legal, and Patient Support Services to improve net sales
- Lead GTN pull-through across all channels and geographies based on formulary position
- Anticipate changes in regulatory and reimbursement landscape; ensure sustained compliance and access
- Develop primary payer research and advisory board programs to close market access knowledge gaps
- Champion launch readiness for landmark AATD therapy (1H 2027) across payer, access, and reimbursement dimensions
- Monitor competitive landscape and payer behavior in partnership with Business Insights & Solutions
- Define KPIs and track progress against access and financial targets
- Balance brand objectives and patient access priorities when they are in conflict
- Build, develop, and lead a high-performing team of 2 direct reports
About youRole Overview:- The Senior Director, US Rare Disease Value and Access owns the value, evidence, pricing, and reimbursement strategy that turns an approved rare disease therapy into a covered, affordable, accessible one. The role spans HEOR and evidence generation, pricing and contracting, payer engagement, and policy - working backwards from what payers need to be convinced of value, often with limited trial data. In rare disease, access is not a downstream function: it is a strategic driver that shapes the commercial case from before launch.
- Beyond access expertise, the Head of Access Strategy must lead the function through the new era of AI-augmented evidence and value work. The six behaviors below apply to the whole leadership team; the ones this role leans on hardest are highlighted.
Leadership Behavior:
What It Means in the New Era1. Leads with AI-augmented judgment- Uses data and AI to decide faster and better - while owning the judgment calls AI cannot make.
2. Orchestrates across boundaries- Delivers through influence, shared goals, and trust as functional silos dissolve - not through positional control.
3. Drives change and adoption- Pulls the team through AI and digital change, creates psychological safety to experiment, and names resistance rather than tolerating it.
4. Obsesses over the patient outcome- Anchors decisions to the patient's find-to-adherence journey, not functional activity metrics; treats advocacy and equity as strategic.
5. Models learning agility- Reskills continuously, experiments, and fails fast in the open so the team does the same.
6. Builds talent density- Runs lean with an elite bar: a few exceptional people, amplified by AI, outproduce larger teams. Makes the hard talent calls, raises the standard, and develops those they keep.
Qualifications:- Bachelor's degree required; advanced degree (MBA, PharmD, MPH, MS, PhD) strongly preferred
- 10+ years of market access and payer experience, gained within the pharmaceutical/biotech industry or from external environments such as payer organizations, managed care, consulting, or health economics firms
- 7+ years of leadership experience managing teams and cross-functional initiatives
- Demonstrated expertise in payer access strategy: pricing, contracting, reimbursement, formulary management
- Proven track record in GTN management and financial modeling
- Strong financial acumen including P&L impact and pricing strategy
- Experience with value proposition development and payer evidence generation
- Experience in rare disease or specialty therapeutics preferred
- Excellent communication, negotiation, and executive influence skills
- Ability to navigate complex, highly regulated environments while managing multiple priorities
Why choose us?- Bring the miracles of science to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
- Lead market access strategy for a high-growth $2.2B rare disease business with clear path to $3.1
- Play a pivotal role in launching a landmark AATD therapy that will transform patient lives
- Join the US Leadership Team and shape payer strategy across the entire rare disease portfolio
- Drive formulary adoption and reimbursement for breakthrough therapies with cutting-edge HEOR, RWE, and payer evidence strategies
- Be part of a mission-driven team chasing the miracles of science to improve patients' lives.
The salary range for this position is:
$206,250.00 - $297,916.66
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.
