Pfizer

Senior Director, Strategy and Portfolio Management

Pfizer$214K — $358K *
Enterprise Technology
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor’s degree in a relevant discipline; advanced degree preferred.
  • 12+ years of experience in pharmaceutical, healthcare, or relevant project management.
  • Exceptional interpersonal and engagement skills to influence decisions and achieve outcomes.
  • Outstanding communication skills, capable of storytelling and delivering compelling presentations.
  • Experience managing large, complex budgets efficiently.
  • Strategic thinker with a collaborative mindset, comfortable co-creating with partners.
  • Proficient in leading within large global matrixed environments, leveraging cross-functional partnerships.
  • Strong analytical and critical thinking abilities with an attention to detail.

Responsibilities

  • Participate in executive decision-making as a member of the CISO, Infrastructure and Cloud Services Leadership Team.
  • Develop and execute the organization’s strategic plan aligned with Pfizer Digital priorities.
  • Act as the principal strategic advisor to the SVP, influencing decisions on financial and operational priorities.
  • Lead governance processes that aid executive decision-making across various initiatives.
  • Establish and govern the enterprise portfolio management framework.
  • Make trade-off decisions to optimize funding and resource allocation for maximized business value.
  • Drive organizational transformation initiatives to improve agility and operational effectiveness.

Benefits

  • Comprehensive health benefits including medical, dental, and vision coverage.
  • 401(k) plan with matching contributions and retirement savings contributions.
  • Paid vacation, holiday, personal days, and medical leave.
  • Paid caregiver and parental leave programs.
  • Relocation assistance based on business needs and eligibility.
Full Job Description

ROLE SUMMARY

The Senior Director, Strategy and Portfolio Management serves as a key member of the CISO, Infrastructure and Cloud Services Leadership Team and acts as the principal strategic advisor to the SVP, CISO, Infrastructure and Cloud Services. This role is accountable for defining, governing, and executing the organization's strategic direction, operating model, financial priorities, portfolio governance, and transformation agenda. 

 

The position provides enterprise-wide leadership across strategy development, business operations, portfolio governance, financial planning, communications, organizational effectiveness, and transformation execution. The Senior Director leads executive decision-support processes, drives prioritization of financial resources, and ensures organizational capabilities, investments, and resources are aligned to enterprise objectives and business outcomes. 

 

Reporting directly to the SVP, this role has broad accountability for shaping how the organization operates, evolves, and delivers value across Security, Infrastructure and Cloud Services. The role leads a team of portfolio, business operations, communications, organizational effectiveness, and change management professionals while providing horizontal leadership across all lines of business. 

 

ROLE RESPONSIBILITIES

The responsibilities include, but are not limited to:

Enterprise Strategy & Leadership 

  • Serve as a standing member of the CISO, Infrastructure and Cloud Services Leadership Team, participating in executive decision-making and shaping organizational strategy, priorities, and operating model direction. 

  • Own the development, execution, and continuous evolution of the organization's strategic plan, ensuring alignment with Pfizer Digital and enterprise priorities. 

  • Act as the principal strategic advisor to the SVP, CISO, Infrastructure and Cloud Services, providing recommendations that directly influence organizational direction, financial priorities, operating model decisions, and business outcomes. 

  • Lead executive governance and decision-support processes, providing insights, recommendations, and options that inform critical leadership decisions across strategy, operations, talent, and transformation initiatives. 

 

Portfolio Governance & Financial Stewardship 

  • Establish and govern the enterprise portfolio management framework across Security, Infrastructure and Cloud Services. 

  • Lead portfolio prioritization and financial governance processes, exercising final authority for portfolio recommendations and financial allocation decisions within delegated financial and governance parameters. 

  • Make trade-off decisions regarding funding, resources, timing, and strategic priorities to maximize business value and organizational outcomes. 

  • Ensure financial allocations and portfolio commitments remain aligned with strategic objectives, risk tolerance, regulatory requirements, and operational commitments. 

  • Partner with Finance leadership to optimize resource deployment strategies, long-range financial planning, and financial performance. 

 

Organizational Transformation & Operating Model Leadership 

  • Own and drive the organizational transformation agenda for the CISO, Infrastructure and Cloud Services organization, including operating model evolution, governance modernization, organizational effectiveness, workforce strategy, and ways of working. 

  • Lead initiatives that redefine how the organization operates, makes decisions, manages priorities, allocates resources, and delivers value across Digital and the enterprise. 

  • Partner with senior leaders to design and implement organizational structures, governance frameworks, and business processes that improve agility, scalability, accountability, and performance. 

  • Establish and sustain a culture of continuous improvement, ensuring the organization continuously evolves to meet changing business and technology needs. 

 

Business Operations & Organizational Performance 

  • Direct all business operations functions, including strategic planning, portfolio governance, financial management, communications, organizational effectiveness, talent planning, and executive reporting. 

  • Establish performance measures, dashboards, and management systems that provide visibility into organizational health, financial performance, strategic progress, and operational effectiveness. 

  • Drive annual strategic planning, operational planning, and business review processes to ensure alignment between priorities, resources, and organizational objectives. 

  • Ensure effective governance, risk management, and decision-making processes across the organization. 

 

Communications & Stakeholder Engagement 

  • Lead organizational communications, executive messaging, leadership forums, and employee engagement strategies to ensure transparency and alignment across stakeholders. 

  • Serve as a trusted advisor to senior leaders and represent the organization in strategic and operational forums. 

  • Build strong partnerships across Pfizer Digital, business leadership, Finance, PX, and enterprise stakeholders to advance strategic priorities and organizational effectiveness. 

 

Leadership & Talent Development 

  • Provide horizontal leadership across multiple business units, fostering collaboration, alignment, and knowledge sharing. 

  • Lead teams responsible for portfolio management, business operations, communications, organizational effectiveness, and change management. 

  • Develop leadership capability, strengthen organizational effectiveness, and cultivate a high-performing, inclusive culture focused on accountability, innovation, and continuous improvement. 

  • Champion diversity, inclusion, and talent development initiatives that support organizational growth and long-term success. 

BASIC QUALIFICATIONS  

  • Bachelor’s degree in a relevant discipline required, advanced degree preferred.  

  • 12+ years of pharmaceutical, healthcare, or other relevant project management experience 

  • Exceptional interpersonal and engagement skills with the ability to establish relationships, influence decisions, and drive to business outcomes.  

  • Outstanding communicator, skilled storyteller, excellent at developing highly visual and effective content, and delivering presentations to a variety of audiences. 

  • Demonstrated ability to develop talent and build effective teams. Passionate about growing, coaching, and mentoring others.  

  • Experience managing large complex dynamic budgets. 

  • Strategic and creative thought partner with ability to lead in strong co-creation and collaboration with Digital and business partners across Pfizer.  

  • Experienced leading in large global distributed matrixed environments. Skilled at utilizing resources outside of direct authority and championing and executing cross-functional horizontal initiatives. 

  • Strong skills in analysis, critical thinking, planning, consensus building, facilitation, negotiation, and the ability to readily learn a new business area. 

  • Excellent organizational skills, detail oriented, able to analyze large volumes of data and quickly derive and communicate key data points and insights. 

 

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS  

20% travel 

Last Date to Apply for Job: 9/16/2026

The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

About Pfizer

Hospira, Inc. is the provider of injectable drugs and infusion technologies. Through its broad, integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees.

Pfizer Careers

Joining Pfizer’s global team offers more than just job opportunities; it’s a chance to be a part of a company that leads with science and innovates for better health. As a leading biopharmaceutical company, Pfizer is at the forefront of transforming lives through innovation, leadership, and diversity. Work You’ll Do At Pfizer, you will collaborate with some of the brightest minds in the industry, engaging in work that enhances global health and saves lives. Our culture thrives on intellectual curiosity, professional growth, and inclusivity, making every day a learning opportunity. Here, your skills will be honed, your professional acumen will be expanded, and you will be part of a team that values the power of diverse insights to drive success. Pfizer’s Leadership and Growth Lead and innovate with Pfizer, where we value the growth of each employee. Our leadership is committed to providing employees with the training and resources needed to excel in their careers. Pfizer offers a variety of career paths, including roles in research, marketing, finance, technology, and more, each offering a unique blend of challenges and rewards. Internship and Employment Opportunities Start your career with Pfizer through our internship programs or dive straight into a full-time position. We are hiring individuals who are passionate about healthcare and who seek to make a difference in the world. Our internships provide invaluable industry experience, networking opportunities, and a potential pathway to full-time employment. Benefits and Culture Pfizer is dedicated to fostering a workplace where all employees feel valued and can achieve their full potential. We offer competitive benefits packages that support the health, well-being, and financial security of our employees and their families. At Pfizer, you’ll find a culture that encourages collaboration, innovation, and continuous learning. Join Our Team Explore the numerous job opportunities at Pfizer by searching open positions that match your skills and interests. We look for driven, curious, and innovative team players who are ready to advance their careers in a transformative company. Stay Connected Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await at Pfizer. Interview and Resume Tips Prepare for your future with Pfizer by utilizing our resources for resume building and interview preparation. We provide guidance on how to effectively showcase your skills and experiences to align with the needs of a position at Pfizer. Our goal is to help you succeed in securing a role that suits your professional goals and personal growth aspirations. Pfizer: A Place Where You Can Make a Difference Every position at Pfizer contributes to our mission of making the world a healthier place. Whether through direct patient care, research innovation, or corporate roles that support our operations, your work will have global impact. Join us in our journey to change lives—explore Pfizer careers today.
Learn more about Pfizer
Size
79,000 employees
Market Cap
$285.9 billion
Industry
Net Income
$9.6 billion
Founded
1849
5 Year Trend
+9%
Revenue
$41.9 billion
NASDAQ

Similar Jobs

More Jobs at Pfizer

More Enterprise Technology Jobs

Find similar Senior Director, Strategy and Portfolio Management jobs: