Pfizer

Senior Director - Open Innovation Lead

Pfizer$214K — $358K *
Pharmaceuticals & Biotech
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • PhD, MD-PhD, or PharmD with 12+ years in research, preferably in Oncology, Immunology, or Metabolic Disease.
  • 5+ years leading pre-clinical research teams to deliver drug candidates from nomination to IND filing.
  • Proficient in evaluating drug candidates and supporting business development efforts.
  • Demonstrated experience managing partnerships in a biopharmaceutical context.
  • Current knowledge of drug discovery, translational development, and applicability of computational technologies.
  • Strong strategic thinker with data-driven decision-making capabilities.
  • Excellent verbal, written, and presentation communication skills.

Responsibilities

  • Serve as a strategic advisor for prioritizing high-impact external innovation opportunities.
  • Lead assessments of molecule-based opportunities, influencing investment and partnership decisions.
  • Evaluate emerging technology platforms for alignment with scientific and business strategies.
  • Advise senior leaders on preclinical and early clinical investment prioritization.
  • Drive connectivity among leaders to align priorities and inform strategies.
  • Synthesize market dynamics and scientific insights to guide portfolio strategy and investment decisions.
  • Champion innovation, partnering with leadership to enhance research and development efforts.

Benefits

  • 401(k) with matching contributions and additional retirement savings contributions.
  • Paid vacation, holidays, personal days, and parental leave.
  • Health benefits including medical, dental, and vision coverage.
  • Support for a healthy work-life balance with a hybrid work model.
  • Relocation assistance may be available based on business needs.
Full Job Description

This role provides leadership for business development-related evaluations, with a particular emphasis on those in research and early clinical development. The position is responsible for identifying, evaluating, and facilitating the securing of drug candidates, technologies, and collaborations that accelerate research and early clinical development in alignment with the strategies of the four therapeutic areas. It also partners with the Discovery Network to champion the evaluation of artificial intelligence, computational technologies, and discovery technologies to enhance the work of Preclinical & Translational Sciences (P&TS) across modalities.

What You Will Achieve

In this role, you will:

  • Serve as a strategic advisor to P&TS and Business Development leadership, shaping the identification, evaluation, and prioritization of high-impact external innovation and partnering opportunities that strengthen the research and early clinical pipeline and advance long-term portfolio objectives.
  • Lead cross-functional strategic assessments of molecule-based opportunities, partnering with P&TS leadership, diligence teams, and Business Development to evaluate scientific, technical, and portfolio fit. Influence investment and partnership decisions through clear articulation of the strategic value, competitive advantage, and potential patient impact of external opportunities.
  • Provide enterprise-level leadership in the evaluation of emerging technology platforms and capabilities, collaborating with P&TS leaders, Discovery Network stakeholders, and Business Development to assess opportunities across modalities and ensure alignment with future scientific and business strategies.
  • Influence portfolio strategy and resource allocation decisions by advising senior leaders on the prioritization of internal and external preclinical and early clinical investments, balancing scientific opportunity, organizational capabilities, and business objectives.
  • Drive strategic alignment across P&TS, fostering connectivity among senior leaders, therapeutic area teams, and functional partners to anticipate emerging scientific trends, align priorities, and inform portfolio and innovation strategies.
  • Direct competitive landscape and scientific intelligence efforts, synthesizing external insights, market dynamics, and emerging science into actionable recommendations that guide portfolio strategy, diligence activities, and research investment decisions.
  • Champion transformative innovation across P&TS, partnering with Discovery Network and functional leaders to identify, evaluate, and advance disruptive experimental, digital, AI-enabled, and computational approaches that accelerate discovery and early clinical development across existing and emerging modalities.
  • Shape organizational culture and operating excellence within P&TS, fostering a high-performing environment characterized by collaboration, transparency, strategic thinking, and accountability while promoting alignment around enterprise priorities and portfolio vision.

Requirements

  • PhD, MD-PhD, or PharmD with 12+ years of industry experience in research within one or more of Oncology, Immunology, or Metabolic Disease. 
  • Experience (5+ years) leading pre-clinical research teams to deliver multiple drug candidates (either small or large molecules) through both candidate nomination and IND filing.  
  • Experience with identifying and evaluating drug candidates to support business development.
  • Experience with multiple internal/external partnerships in a biopharmaceutical environment. 
  • Current knowledge of trends in both drug discovery and translational development.  Strong familiarity with the applicability of computational technologies to modern drug research & development.
  • A proactive and strategic thinker, with strong data-driven decision-making skills
  • Strong verbal, written, and presentation communication skills
  • Highly collaborative with outstanding relationship building skills with both internal company leadership and external development partners.
  • Has a global perspective and mindset, with the ability to work effectively with colleagues from diverse cultures, backgrounds, and geographies.
  • Capacity to adapt to a fast-paced and changing environment.
  • Demonstrates a passion for both science and its application to help patients.

Organizational Relationships:

  • Key point of contact for BD, P&TS Scientific Affairs & Strategy Lead, and P&TS due diligence teams as it relates to both drug candidate-based in-licensing and related partnering activities.
  • Key collaborator for the Discovery Network as it relates to identification and evaluation of innovative approaches in research & early clinical development, including both lab-based and computational technologies.
  • Coordinates with Scientific Operations team and key partners across P&TS to drive a clear and consistent communication rhythm of the Pfizer research and early clinical portfolio across therapeutic areas.
  • Aligns with group leads of P&TS leadership and their direct reports on identifying opportunities for where external innovation can contribute to the development of Pfizer’s research & early clinical portfolio, including for alternative modalities.

Preferred Requirements

  • Experience working in a global or multinational organization biopharma
  • Deep knowledge of therapeutic areas relevant to Pfizer's portfolio
  • Ability to manage multiple priorities and projects simultaneously
  • Excellent interpersonal and relationship-building skills
  • High level of emotional intelligence and adaptability
  • Strong leadership and team management capabilities
  • Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

TRAVEL REQUIREMENTS

Travel up to 20%


Relocation support available

Work Location Assignment:  This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week or more as needed.

#LI-PFE

The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Bus Dev & Strategic Planning

About Pfizer

Hospira, Inc. is the provider of injectable drugs and infusion technologies. Through its broad, integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees.

Pfizer Careers

Joining Pfizer’s global team offers more than just job opportunities; it’s a chance to be a part of a company that leads with science and innovates for better health. As a leading biopharmaceutical company, Pfizer is at the forefront of transforming lives through innovation, leadership, and diversity. Work You’ll Do At Pfizer, you will collaborate with some of the brightest minds in the industry, engaging in work that enhances global health and saves lives. Our culture thrives on intellectual curiosity, professional growth, and inclusivity, making every day a learning opportunity. Here, your skills will be honed, your professional acumen will be expanded, and you will be part of a team that values the power of diverse insights to drive success. Pfizer’s Leadership and Growth Lead and innovate with Pfizer, where we value the growth of each employee. Our leadership is committed to providing employees with the training and resources needed to excel in their careers. Pfizer offers a variety of career paths, including roles in research, marketing, finance, technology, and more, each offering a unique blend of challenges and rewards. Internship and Employment Opportunities Start your career with Pfizer through our internship programs or dive straight into a full-time position. We are hiring individuals who are passionate about healthcare and who seek to make a difference in the world. Our internships provide invaluable industry experience, networking opportunities, and a potential pathway to full-time employment. Benefits and Culture Pfizer is dedicated to fostering a workplace where all employees feel valued and can achieve their full potential. We offer competitive benefits packages that support the health, well-being, and financial security of our employees and their families. At Pfizer, you’ll find a culture that encourages collaboration, innovation, and continuous learning. Join Our Team Explore the numerous job opportunities at Pfizer by searching open positions that match your skills and interests. We look for driven, curious, and innovative team players who are ready to advance their careers in a transformative company. Stay Connected Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await at Pfizer. Interview and Resume Tips Prepare for your future with Pfizer by utilizing our resources for resume building and interview preparation. We provide guidance on how to effectively showcase your skills and experiences to align with the needs of a position at Pfizer. Our goal is to help you succeed in securing a role that suits your professional goals and personal growth aspirations. Pfizer: A Place Where You Can Make a Difference Every position at Pfizer contributes to our mission of making the world a healthier place. Whether through direct patient care, research innovation, or corporate roles that support our operations, your work will have global impact. Join us in our journey to change lives—explore Pfizer careers today.
Learn more about Pfizer
Size
79,000 employees
Market Cap
$285.9 billion
Industry
Net Income
$9.6 billion
Founded
1849
5 Year Trend
+9%
Revenue
$41.9 billion
NASDAQ

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