The Position

Let's do something amazing together! The Sr. Director, Marketing will play a critical role in leading brand strategy and execution for Plozasiran, an siRNA therapy targeting APOC3 for patients with Familial Chylomicronemia Syndrome (FCS) and Severe Hypertriglyceridemia (sHTG). This is a high-visibility leadership role responsible for shaping marketing strategy, building a high-performing team, and driving cross-functional alignment to ensure launch success. Over time, the scope may expand to include additional cardiometabolic indications and pipeline products, including Zodasiran.

Patients are counting on us to deliver with speed and excellence. This role offers the opportunity to shape the commercial future of a first-in-class therapy and make a direct impact on patients living with serious, underserved lipid disorders.

This role is based in Pasadena, California, with an expectation to be in the office five days a week.

Responsibilities

• Lead brand planning, including situation analysis, competitive landscape assessment, strategic priorities, and tactical launch plans.
• Drive product positioning, campaign development, and message development across HCP and patient audiences.
• Develop and implement market development tactics that build awareness of unmet need among key customer segments.
• Design and execute integrated marketing campaigns across HCP promotion, patient marketing, digital, and online media.
• Lead omnichannel campaigns, microtargeting, and next-best-action programs to optimize customer engagement.
• Support planning and execution of national sales meetings.
• Work with Business Analytics to generate market insights and optimize customer communication against launch objectives.
• Manage creative, agency of record, media, digital, and peer-to-peer agency partners.
• Oversee project timelines and budgets; participate in monthly budget forecasting; ensure spend aligns with annual plan.
• Partner with Market Access to advance Arrowhead's patient support services program.

Requirements

• Bachelor's degree required
• 12+ years of pharmaceutical or biotech marketing experience, with 5 years of experience in a leadership role
• Direct product launch experience required
• Demonstrated success building and leading marketing teams in a matrixed organization.
• Strong track record partnering with Medical Affairs, Market Access, and Sales on integrated launch execution
• Demonstrated executive presence with the ability to influence senior leadership, present confidently to executive-level audiences, and represent the brand credibly with external stakeholders including KOLs and industry partners
• Experience managing external agencies and marketing budgets
• Demonstrated ability to coordinate, prioritize and handle multiple priorities and projects simultaneously with keen attention to detail
• Must be comfortable managing multiple competing, frequently shifting priorities, and working through uncertainty
• Minimum travel requirements of 25% of the time

Preferred

• MBA or advanced degree preferred.
• Rare disease, cardiometabolic, or lipid-disorder therapeutic experience strongly preferred
• Experience in cardiometabolic therapeutic area, preferably with a focus on dyslipidemias
• Experience in a smaller, rapidly growing, company

California pay range

$250,000-$275,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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