We are currently seeking a Senior Clinical Trial Manager to join our diverse and dynamic team at ICON. In this critical leadership role, you will oversee the operational delivery of clinical trials from study start-up through closeout, ensuring quality, compliance, and execution against study timelines and objectives.

As the clinical operations lead, you will work cross-functionally with sponsors, investigators, vendors, and internal stakeholders to drive successful study outcomes while identifying and mitigating risks throughout the trial lifecycle.

• Lead the operational delivery of assigned clinical trials, ensuring milestones, timelines, budget expectations, and quality standards are achieved.
• Drive study start-up activities, site activation, enrollment strategies, and study execution through database lock.
• Provide oversight of study progress, monitoring activities, clinical metrics, and site performance.
• Develop and implement effective study oversight plans, monitoring strategies, and risk mitigation approaches.
• Identify operational challenges and proactively implement solutions to ensure successful study delivery.
• Build and maintain strong relationships with sponsors, investigators, vendors, and cross-functional stakeholders.
• Review study performance metrics and provide regular status updates and reporting.
• Support, mentor, and collaborate with Clinical Research Associates (CRAs) and other study team members.
• Ensure all clinical trial activities comply with protocol requirements, ICH-GCP guidelines, and applicable regulatory requirements.

• Bachelor's degree in Life Sciences, Health Sciences, Nursing, Pharmacy, or another relevant scientific discipline, or an equivalent combination of education and experience.
• Significant Clinical Trial Management experience within a CRO (preferred), pharmaceutical, or biotechnology environment.
• Demonstrated ability to successfully lead and deliver clinical studies from start-up through closeout.
• Strong understanding of clinical trial operations, ICH-GCP, and applicable regulatory requirements.
• Experience managing study timelines, budgets, vendors, and cross-functional stakeholders.
• Proven ability to identify risks, solve complex operational challenges, and drive study execution.
• Prior monitoring experience preferred.
• Experience managing global and/or complex clinical trials preferred.
• Ability to travel up to 20%.

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Employment with ICON is contingent upon having the legal right to work in the country where the role is based.

Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.

Benefits may include:

• Competitive base salary and performance related incentives
• Health and wellbeing programmes including medical, dental, and vision coverage where applicable
• Retirement and pension plans
• Life assurance and disability coverage
• Employee assistance programmes and wellbeing resources
• Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.

Visit our to read more about the benefits ICON offers.

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