What You Will Achieve
As a Senior Associate Scientist, you will join Pfizer's Viral Vaccines organization, a team dedicated to advancing innovative vaccines that help protect people from serious infectious diseases around the world. In this role, you will become part of a highly collaborative virology team responsible for generating and supplying viral reagents to support pre-clinical vaccine research. Viruses of particular interest will include Respiratory Syncytial Virus (RSV), Epstein Barr Virus (EBV), and human cytomegalovirus (HCMV), pathogens that contribute to significant disease burden across vulnerable populations worldwide. Responsibilities will include producing and optimizing high-titer virus stocks, maintaining mammalian cell cultures, performing viral characterization assays, managing reagent inventories, and coordinating the distribution of critical viral reagents across vaccine research programs.
Beyond laboratory operations, you will contribute to scientific collaboration and innovation by ensuring data and information transfer between groups, developing and integrating immunoassays, and supporting high-throughput testing activities for non-clinical research programs. Your efforts will help generate the robust scientific data required to assess vaccine performance and guide development strategies.
Your work will be essential to ensuring that research teams have access to the high-quality viral materials needed to evaluate vaccine candidates and accelerate scientific decision-making. The viral reagents, data, and scientific insights you help generate will directly contribute to programs aimed at preventing infectious diseases, improving public health, and bringing promising vaccine candidates closer to the people who need them most. Through your technical expertise, problem-solving abilities, and commitment to quality, you will play an important role in helping Pfizer deliver breakthroughs that change patients' lives.
How You Will Achieve
In this role, you will:
- Conduct various assays to monitor immune responses elicited by vaccine candidates and document laboratory work involving bio-functional assays thoroughly
- Maintain cell lines, process red blood cells weekly, and prepare samples for testing, assisting with molecular and virology work
- Generate plasmid constructs for RNA and reverse genetic virus stocks, optimizing RNA vaccines
- Ensure compliance with SOP guidelines, cGLP, and/or cGMP guidelines, and execute qualifications and validations of new instruments and custom methods
- Contribute to work group goals, collaborate with team members, and participate as a team member
- Prioritize work to meet project deadlines, apply technical skills to assignments, and organize work according to departmental priorities
- Choose between alternatives to solve moderately complex problems, follow procedures with general instructions, and work under moderate supervision with regular review
- Collaborate with the Primary Pharmacology Group to ensure alignment around assay technology selection, assay quality criteria, and validation requirements
- Interact with external vendors to obtain quotes and purchase reagents for clinical testing, and manage manual and robotic sample preparation
- Identify and report experimental problems, troubleshoot causative factors, implement necessary corrections after discussing with the supervisor, and train other analysts on established technologies while managing direct reports
Qualifications
Must-Have
- BA/BS with at least 3 years of experience or MBA/MS with any years of experience
- Hands-on experience in cell culture and cell-based assays
- Proficiency in using relevant software for data analysis
- Fundamental laboratory skills, including quantitative-PCR, molecular biology, western blotting, biochemical assays, and tissue processing
- Strong background in experimental design and result interpretation
- Effective verbal and written communication skills
- Proficiency in using personal computers for word processing, Excel, PowerPoint, and scientific software
Nice-to-Have
- Hands-on experience with mammalian cell culture and flow cytometry
- Practical knowledge in cell culture techniques and flow cytometry analysis
- Experience in drug discovery processes
- Expertise in maintaining and manipulating cell lines for experimental purposes
- Proficiency in analyzing cell populations and their characteristics
- Strong problem-solving skills
- Ability to work collaboratively in a team environment
- Excellent organizational and time management skills
- Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance
PHYSICAL/MENTAL REQUIREMENTS
- Ability to meet the standard requirements for a lab-based role and perform all typical lab related activities (lifting <20 pounds, frequent pipetting, long stretches on feet, etc)
Work Location Assignment: On Premise
The annual base salary for this position ranges from $68,600.00 to $114,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Research and Development
