Senior Associate Scientist - Target Discovery Research, Oncology

Merck Group • $90K — $135K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in a relevant scientific discipline with 2+ years of laboratory experience or Master's degree with 1+ year of experience.
  • Proficiency in mammalian cell culture techniques and aseptic methodologies.
  • Hands-on experience with functional genomics and gene-editing technologies, including CRISPR.
  • Strong skills in molecular biology techniques such as western blotting and qPCR.
  • Experience in flow cytometry and cell imaging technologies.

Responsibilities

  • Conduct in vitro experiments involving cell culture and molecular biology techniques.
  • Perform CRISPR-based genome editing for target validation.
  • Execute experimental workflows, troubleshooting, and optimizing protocols.
  • Collaborate with cross-functional teams to support diverse target research.
  • Document and analyze experimental data using ELNs and analytical software.

Benefits

  • Health insurance and paid time off (PTO).
  • Retirement contributions and performance-based bonuses.
  • Access to professional development opportunities.
Full Job Description
Your Role:

The EMD Serono Research and Development Institute in Billerica, MA, is hiring a Senior Associate Scientist within our Target Discovery Research group. The Senior Associate Scientist will be responsible for conducting in vitro experiments, including cell culture, western blots, PCR, as well as overexpression, knockdowns, and CRISPR-based genome editing experiments to facilitate target identification and validation. This role offers a laboratory-based opportunity to contribute to the forefront of cancer research within a research-based drug discovery company.

Who You Are:

Minimum Qualifications:
  • Bachelor's degree in Molecular Biology, Cell Biology, Biochemistry, or other Scientific discipline with 2+ years of hands-on laboratory experience, including aseptic techniques for handling mammalian and/or cancer cell lines

OR
  • Master's degree in Molecular Biology, Cell Biology, Biochemistry, or other Scientific discipline with 1+ year of hands-on laboratory experience, including aseptic techniques for handling mammalian and/or cancer cell lines


Preferred Qualifications:
  • Demonstrated proficiency in mammalian cell culture techniques, including routine cell line maintenance, transfection, and isolation of genetically engineered clones
  • Ability to operate in a rapidly evolving drug discovery environment, balancing competing priorities while supporting research efforts across diverse target classes, technologies, and therapeutic modalities
  • Hands-on experience with functional genomics and gene-editing technologies, including RNA interference (RNAi) and CRISPR-based genome engineering
  • Strong expertise in molecular and cellular biology techniques, including western blotting, AlphaLISA, qPCR/TaqMan assays, and related analytical methods
  • Experience with flow cytometry (FACS) for cellular phenotyping, transfection assessment, cell sorting, or other cell-based applications
  • Experience with cell imaging technologies, including microscopy, Incucyte live-cell imaging, or other high-content imaging platforms
  • Excellent analytical, troubleshooting, and problem-solving skills, with the ability to optimize experimental workflows and interpret complex data
  • Strong written and verbal communication skills, with a proven ability to collaborate effectively in a cross-functional team environment
  • Proficiency with Microsoft Office applications (Word, Excel, and PowerPoint), GraphPad Prism, and electronic laboratory notebooks (ELNs) for data analysis and documentation
  • Strong organizational skills and the ability to manage multiple priorities in a fast-paced research environment
  • A self-motivated and detail-oriented approach, with a commitment to scientific rigor and high-quality experimental execution


Pay Range for this position: $90,400 - $135,700

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

RSREMD

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