AstraZeneca

Scientist, TRS

AstraZeneca$92K — $138K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 2+ years of research experience in academic or industry settings, preferably in hematological malignancies.
  • Proficiency in cell culture and immune-based assays (e.g., Western Blot, ELISAs, Flow Cytometry).
  • Experience with gene expression techniques such as NGS and qPCR.
  • Ability to write technical reports and SOPs.
  • Experience with biospecimen management and general lab operations.
  • Strong organizational and interpersonal skills for effective cross-functional collaboration.

Responsibilities

  • Lead the execution of non-clinical and translational experiments in hematological tumor biology.
  • Develop and validate translational assays for various hematological malignancies.
  • Communicate scientific findings clearly through reports and presentations to stakeholders.
  • Ensure compliance with internal SOPs and external regulations in all research activities.
  • Apply reverse translation methods to uncover resistance mechanisms in treatments.

Benefits

  • Qualified retirement programs
  • Paid time off including vacation and holidays
  • Health, dental, and vision insurance coverage
  • Eligibility for short-term incentive bonuses
  • Opportunities for equity-based awards and commissions for certain roles
Full Job Description

Introduction to role

Are you ready to turn innovative translational science into meaningful progress for people living with blood cancers?As a Scientist, within the Translational Research Science Haem R&D team, you will be part of high-caliber team to design and deliver translational assays and data that steer clinical trials, sharpen pre-clinical decisions, and unlock new combinations across indications. Your work will have a special focus on generating impactful data, ensuring our programs move forward with clarity and confidence. 

In this role, you will shape how we understand tumor biology, minimal residual disease, and resistance mechanisms—translating insights into actions that accelerate our pipeline. You will connect laboratory discovery to clinical strategy by integrating translational scientists with discovery, data science, and clinical teams. Do you thrive at the interface of bench science and patient impact, where meticulous execution meets critical thinking?

Accountabilities

  • Reporting to a Sr Scientist/Associate Director, lead hands-on execution of non-clinical and translational experiments focused on hematological tumor biology. Tasks include assessing target expression post-treatment, applying reverse translation to reveal resistance mechanisms, and informing new combination strategies across multiple indications. 

  • Assay development for hematologic Malignancies: Build and validate translational assays supporting programs across different heme indications to broaden portfolio impact.

  • Scientific communication:write technical reports, SOPsand present data to stakeholders, that clearly convey methodologies, findings, and implications for development.

  • Quality and compliance: Perform all duties in compliance with internal SOPs and external regulations, embedding standard methodologies and reproducibility in every study.

Required technical skills and experience

  • At least 2 years of research experience in academic or industry setting. Previous translational research experience in hematological malignancies is highly desired.

  • Proficiency in cell culture techniques, immune-based assays (Western Blot, ELISAs, Flow Cytometry, Luminex/MSD), gene expression (NGS, qPCR and/or Quantigene)and data analysis platforms (e.g. FlowJo, Prism, R, OMIQ) is required.  

  • Experience writing technical reports and SOPs is required.

  • Experience with biospecimen managing and handling (sample tracking software’s, liquid nitrogen storage systems) and general lab management (e.g. supplies ordering and inventory)

  • Excellent organizational and interpersonal skills for cross-functional interactions.

  • Dedication to carrying out all duties according to internal SOPs and external regulations. 

When we put unexpected teams in the same room, we ignite bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and ambitious world!

Bring your translational research experience to a place where science moves fast and your work steers pivotal decisions—step into this Associate Director role and help shape the future of hematology today!

The annual base pay for this position ranges from $92,252.00 - $138,378.00. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. 

 

 

Date Posted

09-Jul-2026

Closing Date

07-Aug-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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