About the job Scientist II
37218960 Scientist II Ridgefield, CT, 24 Months Sigma Inc is looking for a Scientist to work onsite with our team in Ridgefield, CT.
Responsibilities: - Develop and optimize image analysis pipelines for 2D and 3D biomedical images.
- Perform quantitative analysis of histology, IHC, IF, and multiplex imaging data.
- Apply classical image processing and machine learning methods for feature extraction, segmentation, and classification. Including integration of multiple image analysis platforms (e.g., HALO, Visiopharm, QuPath).
- Collaborate with pathologists, biologists, and data scientists to define analytical endpoints.
- Validate image derived biomarkers and ensure analytical rigor.
- Document workflows and ensure reproducibility of analyses.
- Support interpretation and visualization of image based data for scientific reports.
- Help cross lab collaboration through image and algorithm transfer.
Requirements: - Bachelor's Degree from an accredited institution with three-plus (3+) years of experience in related scientific discipline or Master's Degree from an accredited institution in related scientific discipline or equivalent experience in related field.
- Proficient in scientific programming languages (R, Python) and have experience applying machine learning techniques, preferably in pathology images (H&E/IHC/mIF).
- Extensive experience applying machine learning techniques.
- Experience in cell image analysis and marker quantification from multiplex IHC for digital pathology.
- Experience with some of these image analysis tools (e.g., HALO AI, Visiopharm, QuPath, CellProfiler).
- Strong problem-solving and independent thinking skills.
- Experience in tumor immunology and histopathology is a plus.
- Previous experience in industry and biotech is desired.
