Allen Institute for Brain Science

Scientist II - Molecular and Proteomic Immunology

Allen Institute for Brain Science$105K — $130K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. or equivalent in life sciences discipline
  • 3+ years of postdoctoral experience
  • Strong background in molecular biology including NGS platforms
  • Experience in cellular immunology
  • Proven success in troubleshooting and innovation in research
  • Independent data analysis skills using coding languages (R, Python, Bash)
  • Exceptional oral and written communication skills

Responsibilities

  • Support development of molecular and proteomic technologies for immunology insights
  • Develop cellular engineering approaches to study immune function
  • Design, execute, and analyze immunological studies using various cell sources
  • Collaborate with a team to meet project timelines
  • Innovate new assays and technologies to advance research goals

Benefits

  • Medical, dental, and vision insurance for employees and their families
  • Basic life insurance provided
  • Eligibility to enroll in 401k plan
  • Generous paid time off
  • Potential for work visa sponsorship and relocation assistance
Full Job Description
Scientist II • Molecular and Proteomic Immunology

We are searching for an exceptional molecular immunologist (Scientist II) to join a team focused on using and developing molecular and/or proteomic approaches to comprehensively study the interactions of the immune system. Specific responsibilities will include the design and development of new assays, technologies, and in vitro and ex vivo immunologic studies along with the analysis and synthesis of data generated through our cellular, molecular and proteomic platforms or their derivatives. A flexible and creative mindset along with the ability to function in a team to bring projects to completion on a timeline is essential.

The successful candidate will have a strong background in molecular and/or proteomic methodologies along with prior neuroscience and/or immunology experience. Strongest consideration will be given to candidates with a proven track record in identifying and progressing novel hypotheses forward in discovery research and technology development. This position is expected to last through December 2028 based on business needs and funding.

Essential Functions
  • Support the development and application of molecular and proteomic technologies to drive biological insight in the context of immunology. Examples include spatial and droplet based NGS platforms such as Xenium and 10x FLEX or REFLEX
  • Development of cellular engineering approaches for dissecting immune function. Examples could include molecular recorder systems and high throughput screens
  • Design, execute and analyze in vitro and ex vivo immunological studies utilizing cell lines, primary cells, and tissues to develop and test hypothesis, possibly including the utilization of genetic mouse models
  • Collaboration with a team to bring projects to completion on a timeline

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management's assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience
  • Ph.D. or equivalent combination of degree and experience in a life sciences discipline
  • 3+ years of postdoctoral experience

Preferred Education and Experience
  • A strong background in molecular biology including NGS platforms
  • Experience in cellular immunology
  • Direct experience with advanced approaches in deconstructing immunologic mechanisms & testing hypotheses (e.g. targeted mutagenesis using CRISPR/Cas9, phenotypic screening, antibody-based immune modulation, lentiviral work, cell culture, etc.)
  • Proven success in troubleshooting and innovation on existing platforms, including publications and/or patents
  • Demonstrated ability to independently analyze data through coding languages (R, python, bash, version control)
  • Exceptional oral and written communication skills and ability to effectively present complicated concepts internally and externally in a cross-discipline environment

Work Environment
  • Working in a laboratory environment with potential exposure to lasers, biohazards

Physical Demands
  • Occasional lifting to 30 pounds
  • Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
  • Stooping, bending, crouching

Position Type/Expected Hours of Work
  • May need to work outside of standard working hours at times
  • This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis. We are a WashingtonState employer; any remote work must be performed in Washington State.
  • This position is expected to last through December 2028, based on business needs and funding

Additional Eligibility Qualifications
  • All employees who work with live animals must complete an Occupational Health medical history form and/or consultation with an Occupational Health Provider and receive clearance to work with animals. Depending on your health history and job responsibilities, an annual respiratory health screening and clearance to use a respirator may also be required.

Additional Comments
  • **Please note, this opportunity may offer work visa sponsorship**
  • **Please note, this opportunity may offer relocation assistance**

Annualized Salary Range
  • $105,600 - $130,650 *

* Final salary depends on required education for the role, experience, and level of skills relevant to the role, along with work location, where applicable.

Benefits
  • Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute's Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute's 401k plan. Paid time off is also available as outlined in the Allen Institute's Benefits Guide. Details on the Allen Institute's benefits offering are located at the following link to the Benefits Guide: https://alleninstitute.org/careers/benefits.

About Allen Institute for Brain Science

The Allen Institute for Brain Science is a division of the Allen Institute, based in Seattle, Washington, that focuses on bioscience research. Founded in 2003, it is dedicated to accelerating the understanding of how the human brain works. With the intent of catalyzing brain research in different areas, the Allen Institute provides free data and tools to scientists. Started with $100 million in seed money from Microsoft co-founder and philanthropist Paul Allen in 2003, the institute tackles projects at the leading edge of science—far-reaching projects at the intersection of biology and technology. The resulting data create free, publicly available resources that fuel discovery for countless researchers. Hongkui Zeng is the director of the institute.
Learn more about Allen Institute for Brain Science

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