Scientist

Aclaris Therapeutics, Inc.

$88K — $105K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • B.S. in a relevant scientific field plus 5+ years of experience in drug discovery
  • M.S. in a relevant scientific field with 2+ years experience preferred
  • Proficient in designing and executing various biological assays
  • Familiar with biochemistry, cell biology, immunology, and pharmacology techniques
  • Demonstrated critical thinking and data interpretation skills

Responsibilities

  • Conduct hands-on laboratory research focused on drug discovery
  • Execute models and assays, including plate-based and cell-based systems
  • Develop and implement experimental protocols using various methods
  • Identify essential reagents and ensure lab equipment availability
  • Analyze assay data and communicate results to teams and clients
  • Maintain high-quality documentation and uphold data integrity
  • Follow laboratory safety practices and collaborate across functions

Benefits

  • Commitment to laboratory safety and quality practices
  • Fast-paced drug discovery environment
  • Opportunity for cross-functional collaboration
  • Possibility to contribute to innovative scientific research
Full Job Description
Description

Position Summary:

The Scientist, Biology focuses on the design, development, and execution of cellular, immunological and/or other biological/pharmacological assays that are critical for the company to meet its goals. In this position, you will participate in both internal or contract drug discovery and biological research, addressing complex scientific questions in a fluid team environment. Efficient and effective execution is critical.

Essential Duties and Responsibilities:
• Hands-on laboratory researcher focused in drug discovery
• Effectively carry out models and assays in the areas of biochemistry, cell biology, immunology, molecular biology, and/or pharmacology
• Devise, design and execute experimental protocols using standard in-house methods, methods from partner companies or from the literature
• Define the necessary reagents and supplies to conduct the desired assay; ensure that the necessary equipment is available to conduct the assay.
• Assay execution, data analysis and effective oral and written communication of results including interpretation of findings and suggested next steps - both internally and to clients
• Strong emphasis on high-quality documentation and data integrity (clear, timely recordkeeping)
• Commitment to laboratory safety, quality practices, and effective cross-functional collaboration in a fast-paced drug discovery environment

Additional Responsibilities:
• Report writing and preparation of slide decks

Requirements

Required Education and Experience:

B.S in relevant scientific field with 5+ years relevant experience in drug discovery

Preferred Education and Experience:

M.S. in relevant scientific field with 2+ years relevant experience in drug discovery

Required Knowledge, Skills, Abilities & Behaviors:
  • Proficiency in the design and execution of assays including several of the following:
    o Plate based assays/medium to high throughput screening
    o Mammalian cell culture and cell-based assays using cells lines and primary human immune cells
    o Molecular biology, DNA/RNA isolations, qRT-PCR
    o ELISA, Western blots, multiplex analysis
    o Complex multi-parametric flow cytometry assays
    o Biomarker assay development and execution for clinical studies
    o Desired (not required): Bioinformatics data analysis and interpretation (e.g., gene expression, proteomics, pathway analysis)
    • Ability to organize time and work independently
    • Critical thinking and data interpretation skills
    • Ability to work in a team environmentwith cross functional teams
    • Multitasking capabilities and interest in working in an environment with quickly changing responsibilities
    • Excellent oral and written communication skills
    • Ability to handle confidential material

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