Roche

Scientist 3 - Nucleic Acid Technologies

Roche$103K — $192K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master's or PhD in Biological Sciences or related field with 1+ years of industry or academic experience.
  • Hands-on experience with molecular biology techniques including sequence design, cloning, and PCR.
  • Practical experience with NGS library preparation and data analysis platforms.
  • Strong communication skills and collaborative mindset with a willingness to learn.
  • Ability to analyze complex datasets using programming tools like R or Python.

Responsibilities

  • Design and execute innovative experiments to support therapeutic programs.
  • Optimize workflows for increased testing efficiency and dataset dimensionality.
  • Conduct early assessments of high-priority biological questions and emerging technologies.
  • Perform key laboratory techniques including qRT-PCR and mammalian cell culture.
  • Analyze complex datasets and present findings to cross-functional teams.
  • Collaborate actively in a fast-paced research environment.

Benefits

  • Comprehensive healthcare coverage including dental and vision plans.
  • 401(k) plan with company match to support retirement savings.
  • Generous paid time off and holiday leave to ensure work-life balance.
  • Access to employee wellness programs and resources for mental health support.
Full Job Description
We are looking for an individual to join our Nucleic Acid Technologies team, which leverages innovative molecular and cellular technologies to advance Genentech's therapeutic programs across mRNA, nucleic acid based medicines (ASO/siRNA), and novel modalities. Our team supports pipeline progress through implementation of established workflows, assay and process improvements, as well as the development of new experimental capabilities that increase efficiency and dataset dimensionality. Additionally, we serve as an incubator for novel modalities and emerging technologies, conducting early assessments of high-priority biological questions and modality-enhancing tools that can enable future therapeutic opportunities.

The Opportunity
  • Design and execute experiments leveraging innovative molecular and cellular technologies to advance therapeutic programs across mRNA, nucleic acid-based medicines (ASO/siRNA), and novel modalities.
  • Optimize experimental workflows and develop new capabilities to increase testing efficiency and dataset dimensionality.
  • Serve as an incubator for emerging technologies, conducting early assessments of high-priority biological questions that enable future therapeutic opportunities.
  • Perform techniques such as qRT-PCR, NGS library preparation, mammalian cell culture, transfection/electroporation, and cell-based screening.
  • Analyze complex datasets using platforms and programming tools (e.g., Benchling, Snapgene, R, Python) and present findings to cross-functional partners.
  • Collaborate closely with team members and project partners in a fast-paced, high-impact research environment.


Who You Are
  • Hold a Master's or PhD degree in Biological Sciences (Genetics, Cell Biology, Molecular Biology, Biochemistry, Genome Engineering, or a related field) with 1+ years of relevant industry or academic experience.
  • Demonstrate hands-on experience with molecular biology techniques (sequence design, cloning, PCR, qRT-PCR) and mammalian cell culture.
  • Possess practical experience with NGS library preparation and data analysis platforms.
  • Show excellent written and verbal communication skills with a strong collaborative mindset and eagerness to learn new scientific capabilities.


This position is not eligible for relocation benefits.

This position is located in South San Francisco and is an on-site laboratory research position.

The expected salary range for this position based on the primary location of California is $103,400.00 - 192,000.00 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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