Full Job Description
We are seeking a Lab Manager to support a LNP and RNA Process Development team. The successful candidate will have a passion for driving efficient lab operations through excellence in la equipment maintenance, raw material inventory management, and execution of routine analytical assays. The successful candidate will have a desire to contribute to a team focused on establishing science-based manufacturing solutions for complex nucleic acid-based products.
- Maintain a safe and high performing laboratory.
- Support continuous improvement initiatives related to lab operations.
- Build and maintain process development specific raw material and consumables inventory systems.
- Prepare buffers, reagents, and stock solutions used for process development activities, following established recipes.
- Maintain detailed preparation records in an electronic lab notebook (ELN).
- Assist with routine maintenance tracking and upkeep of laboratory equipment used in process development.
- Build and maintain equipment maintenance program. for Agilent HPLC, Akta Avant preparative liquid handling, and capillary gel electrophoresis (CGE) systems.
- Opportunity to perform routine analytical tests to support understanding of RNA technology and processes; analytical assays include HPLC, CGE, and ELISA-based methods.
- Opportunity to write lab maintenance protocols, SOPs, contribute to the weekly lab operations meeting, and track and analyze lab efficiency metrics.
- Opportunity to collaborate with external vendors and cross-functional teams including analytical development, as well as the facilities and operations team.
Qualifications
Minimum Required Qualifications:
- B.S./MS degree in biological sciences, chemistry, or biomedical/chemical engineering (or related field) with at least 3 years of relevant industry laboratory experience
- Experience with the operation and maintenance of equipment commonly used in the process development of nucleic acids, including Atka Avant chromatography systems and Agilent HPLC systems.
- Knowledge of inventory management systems and reagent/buffer preparation best practices.
- Strong understanding of laboratory operations and safety protocols.
- Proven ability to manage multiple priorities and work independently.
- Excellent organizational skills and attention to detail.
- Self-motivated with the ability to identify and solve problems proactively.
- Ability to coordinate with scientists, vendors, and service providers.
- Proficiency with MS Office Suite (Word, PowerPoint, Excel).
- Strong work ethic and excitement for being part of an integrated operations team.
- Must be able to work in an active lab environment.
Preferred Qualifications:
- Knowledge of nucleic acid (mRNA, gRNA), LNP, and/or biologics process development.
- Knowledge of analytical methods used for nucleic acid and/or biologics process development, including HPLC, CGE, or ELISA experience.
- Authorization to work in the United States indefinitely without restriction or sponsorship.
Additional Information
The position is full-time, Monday-Friday, 8am-5pm with overtime as needed. Candidates living within a commutable distance of Boston, MA are encouraged to apply.
Excellent full-time benefits include:
- Comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
- Eligibility for yearly goal-based bonus & merit-based increases
- Compensation: $36.00-$42.00 per hour