Research Scientist

University of Virginia

$80K — $95K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in molecular biology, biochemistry, or biophysics required.
  • 4+ years of relevant lab experience required, with focus on protein biochemistry and lipid biophysics.
  • Proven expertise in protein expression, isolation, and biophysical characterization.
  • Experience in statistical and multivariate data analysis.
  • Ability to adapt experimental methods and procedures based on research needs.

Responsibilities

  • Establish and maintain mammalian expression systems for protein production.
  • Isolate membrane proteins for lipidomics studies.
  • Conduct data analysis and interpret results from lipidomic experiments.
  • Prepare manuscripts and research reports for publication.
  • Train and support other staff on laboratory procedures and techniques.
  • Interfacing and collaborating across multiple research labs.

Benefits

  • Access to advanced research facilities and collaborative opportunities across multiple labs at a reputable institution.
  • Engagement in a diverse range of cutting-edge research projects.
  • Potential for professional development and training in specialized areas.
  • Opportunity to contribute to high-impact scientific publications.
  • Flexible work environment with a focus on research advancement.
Full Job Description
The Department of Molecular Physiology and Biological Physics at the University of Virginia School of Medicine seeks a Staff Scientist for a collaborative project between the Levental, Bao, Kenworthy, and Kiessling/Tamm groups.
The Staff Scientist will investigate the hypothesis that proteins recruit specific paralipidomes by purifying membrane proteins from mammalian expression systems and facilitating mass spec based lipidomic analysis. Primary responsibilities will include establishing and maintaining mammalian expression systems for large-scale membrane protein production, membrane protein isolation in sufficient yields for lipidomics, data analysis and interpretation, as well as manuscript preparation. It is expected that these tasks will require significant methods development, as various aspects of the project are being newly established. Another key aspect of the role is interfacing across four labs.
Staff Scientists provide technical lab support by performing complex lab and research related tasks. They act as specialists on research methods and equipment functions specific to research projects. They have the authority to adapt methods and procedures to meet the needs of research. They are distinguished from Lab Technicians by the types and duration of assignments, as well as the skills and expertise necessary to serve as resources on non-routine problems. Staff Scientists perform daily activities without supervision; their longer-term assignments require greater oversight.

  • Specialize in protein expression, isolation, biophysical characterization, and lipidomics data analysis. Demonstrate expertise in troubleshooting problems and recommending solutions.
  • Assist in evaluation of research methods, procedures, and techniques based on established objectives.
  • Provide basic assistance to researchers in manipulating, computing, and analyzing data. Evaluate experiment results using statistical and multivariate analyses. Research, compile, and maintain complex statistical, numerical, and computerized reports.
  • Perform library and literature research.
  • Assist in training other staff members on procedures. Explain work and adapt general methods and procedures to meet research needs.
  • In addition to the above job responsibilities, other duties may be assigned.

MINIMUM REQUIREMENTS
Education: PhD in molecular biology/biochemistry/biophysics required.
Experience: 4+ year of relevant lab experience required, including protein biochemistry and lipid biophysics.
Licensure: None.

TO APPLY:

Applicants apply HERE. Internal applicants may search and apply for jobs on the UVA Internal Careers website . Include the following documents:
  • CV/resume
  • Cover letter

All documents can be loaded into the resume submission field, multiple documents can be submitted into this one field. Internal applicants must apply through their UVA Workday profile. Incomplete applications will not be considered. Before a formal offer of employment is extended, the selected candidate will undergo a background check per university policy. This position is restricted and contingent upon the continuation of funding. This position will remain open until filled.

For further information about the position, please contact Jon Stafford via email at [redacted] . For questions regarding the application process, please contact Eric Allen, Academic Recruiter, at [redacted]

PHYSICAL DEMANDS

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.

MINIMUM REQUIREMENTS

Education: Requires a doctoral degree or master's degree with significant experience.

Experience: None

Licensure: None

PHYSICAL DEMANDS

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs.

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