Abbott

Research Associate - Chemistry/Biochemistry

Abbott • $73K — $116K *
San Diego, CA 92154In-Person
Pharmaceuticals & Biotech
Less than 5 years of experience
Today
Be an Early Applicant
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Chemistry, Biochemistry, Analytical Chemistry, Molecular Biology, or a related field.
  • 2-5 years of laboratory experience in relevant scientific disciplines.
  • Hands-on experience with oligonucleotide synthesis, cleavage, and deprotection.
  • Familiarity with analytical methods like HPLC and mass spectrometry.
  • Strong organizational skills for maintaining laboratory documentation.
  • Excellent attention to detail and commitment to quality.
  • Strong communication, teamwork, analytical, and problem-solving skills.

Responsibilities

  • Perform synthesis of DNA and RNA oligonucleotides using automated synthesizers.
  • Conduct oligonucleotide cleavage, deprotection, purification, and characterization.
  • Purify oligonucleotides using various chromatography techniques.
  • Perform analytical testing with HPLC, UV-Vis spectroscopy, and LC-MS.
  • Maintain accurate laboratory documentation of procedures and results.
  • Support assay and product development teams with high-quality oligonucleotide feedback.
  • Execute biochemical experiments and prepare samples under supervision.

Benefits

  • Collaborative work environment in a multidisciplinary team.
  • Hands-on laboratory experience with advanced oligonucleotide applications.
  • Opportunity to contribute to innovative diagnostic technologies.
  • Professional development and training opportunities available.
  • Stable work hours with no required travel.
Full Job Description
JOB DESCRIPTION:

The Opportunity

Abbott Rapid Diagnostics is seeking a highly motivated Research Associate II -Chemistry/Biochemistry to join our Research & Development team in San Diego, California. In this hands-on laboratory role, you will support the synthesis, purification, characterization, and evaluation of oligonucleotides used in diagnostic applications. The successful candidate will work closely with multidisciplinary teams to deliver high-quality oligonucleotide reagents that enable the development of innovative diagnostic technologies

What You'll Do
  • Perform synthesis of DNA and RNA oligonucleotides using automated oligonucleotide synthesizers.
  • Conduct oligonucleotide cleavage, deprotection, purification, and characterization using established laboratory methods.
  • Purify oligonucleotides using reverse-phase HPLC, ion-exchange HPLC, or cartridge-based purification systems.
  • Perform analytical testing using HPLC, UV-Vis spectroscopy, LC-MS, and related analytical techniques.
  • Maintain accurate laboratory documentation, including experimental procedures, synthesis records, yields, and quality-control results.
  • Support assay development and product development teams by providing high-quality oligonucleotide and technical feedback.
  • Execute biochemical experiments and sample preparation procedures under supervision.
  • Maintain laboratory equipment and perform routine preventative maintenance and calibration


Required Qualifications
  • Bachelor's degree in Chemistry, Biochemistry, Analytical Chemistry, Molecular Biology, or a related scientific discipline.
  • 2-5 years of laboratory experience in chemistry, biochemistry, molecular biology, or related fields.
  • Hands-on experience with oligonucleotide synthesis, cleavage, and deprotection techniques.
  • Familiarity with analytical characterization methods such as HPLC, UV-Vis spectroscopy, and mass spectrometry.
  • Strong organizational skills with the ability to maintain accurate laboratory records and documentation.
  • Demonstrated attention to detail and commitment to producing high-quality results.
  • Excellent communication, teamwork, analytical, and problem-solving skills


Preferred Qualifications
  • Experience operating and maintaining automated oligonucleotide synthesizers (e.g., Dr. Oligo, MerMade, or equivalent systems).
  • Hands-on experience with post-synthetic oligonucleotide modification and conjugation chemistry involving fluorophores, quenchers, or other ligands.
  • Strong understanding of solid-phase oligonucleotide synthesis processes and common oligonucleotide modifications, including fluorescent labels.
  • Experience with oligonucleotide purification using reverse-phase and ion-exchange chromatography.
  • Proficiency with analytical platforms including Agilent, and/or ÄKTA chromatography systems.
  • Experience with LC-MS analysis for oligonucleotide characterization.
  • Knowledge of solid-phase organic synthesis principles and their application to oligonucleotide chemistry.
  • Experience supporting diagnostic assay development or molecular diagnostics projects


The base pay for this position is
$73,900.00 - $116,000.00
In specific locations, the pay range may vary from the range posted.

JOB FAMILY:
Research and Discovery

DIVISION:
ID Infectious Disease

LOCATION:
United States > San Diego : 4545 Towne Center Court

ADDITIONAL LOCATIONS:

WORK SHIFT:
Standard

TRAVEL:
No

MEDICAL SURVEILLANCE:
Not Applicable

SIGNIFICANT WORK ACTIVITIES:
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day), Continuous standing for prolonged periods (more than 2 consecutive hours in an 8 hour day), Keyboard use (greater or equal to 50% of the workday), Routine work with chemicals

About Abbott

Abbott Careers

Joining Abbott means becoming part of a globally diverse team dedicated to making a lasting impact on human health. As a leader in healthcare innovation, Abbott provides a dynamic workplace where careers flourish through growth, leadership, and diversity training.

Opportunities at Abbott

Explore a world of opportunities with our team. Whether you're seeking job opportunities in engineering, marketing, research, or healthcare, Abbott offers a variety of positions that allow professionals to grow their careers. Our commitment to diversity and innovation is evident in every aspect of our work, fostering an inclusive culture that values each team member's contribution.

Work You'll Do

At Abbott, every role contributes to our mission of helping people live fuller lives through better health. From groundbreaking research in medical devices to advancements in pharmaceuticals, our team is at the forefront of healthcare innovation. By joining Abbott, you are not just accepting a job; you are embarking on a path of professional and personal growth.

Internship Programs

Kickstart your career with an Abbott internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at Abbott work on projects that matter, gaining the experience and knowledge necessary to succeed in their future careers.

Professional Development

Abbott is dedicated to the continuous professional development of its employees. With access to cutting-edge technology, leadership programs, and diversity training, our team members are equipped to lead and innovate within the healthcare industry. We support your career journey with robust training programs, mentorship, and opportunities for networking and professional growth.

Benefits and Culture

Our employees enjoy comprehensive benefits designed to support their life and well-being. From health insurance to retirement plans, we ensure our team has everything they need to thrive. Abbott's culture is built on a foundation of respect and integrity, united by a shared commitment to improving health outcomes.

Join Our Team

Discover the impact you can make with a career at Abbott. We are hiring individuals who are passionate, curious, and driven to lead. Search open positions that match your skills and interests on our Jobs page. Prepare your resume, sharpen your interview skills, and get ready to join a team that's at the cutting edge of healthcare solutions.

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Explore Abbott

With a commitment to improving life through innovation, leadership, and diversity, Abbott is a place where you can fulfill your potential. See what exciting and rewarding opportunities await at Abbott by exploring our career opportunities today.

SEARCH ABBOTT JOBS

Join us in our mission to make the world a healthier place through innovation, leadership, and diversity. Your journey to a fulfilling career at Abbott starts here.
Learn more about Abbott
Size
113,000 employees
Market Cap
$189 billion
Industry
Healthcare
Net Income
$4.4 billion
Founded
1944
5 Year Trend
+15.6%
Revenue
$34.6 billion
NASDAQ
ABT
* Ladders Estimates

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