Career CategoryScientific
Job DescriptionProcess Development Senior Principal Scientist BioconjugatesWhat you will doLet's do this. Let's change the world. In this vital role you will join Amgen's DSTS group within Process Development (PD) is responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development.
Amgen is currently seeking a talented Senior Principal Scientist who will lead a multidisciplinary team of chemists and chemical engineers in the development of efficient and sustainable manufacturing processes for bioconjugates, including antibody drug conjugates (ADCs), drive technology innovation, provide technical expertise, and develop and mentor staff within the organization. The successful candidate for this role will be a people-centered leader with deep expertise in bioconjugation process development and industrialization of bioconjugation manufacturing processes with a proven track record of scientific innovation and leadership within the pharmaceutical industry. The role will be located at our Thousand Oaks, California campus.
- Lead a multidisciplinary project team in the development of sustainable and cost-effective processes for bioconjugate manufacturing at all stages of clinical development
- Drive bioconjugation technology innovation
- Support cGMP manufacturing and technology transfer to GMP production facilities
- Develop strategies to ensure process performance through process understanding, modeling and characterization
- Guide successful completion of project deliverables and ensure timelines are met
- Work cross-functionally to deliver regulatory documents and support regulatory filings
- Serve as a technical expert and keep current in the field of bioconjugation manufacturing
- Coach and provide career and scientific / technical advice to colleagues within the organization
What we expect of youWe are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.
Basic Qualifications:- Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 3 years of Scientific experience
OR - Master's degree and 6 years of Scientific experience
OR - Bachelor's degree and 8 years of Scientific experience
Preferred Qualifications:- Doctoral degree and 5+ years in the pharmaceutical industry with expertise in bioconjugate process development, preferably in Antibody Drug Conjugates (ADCs) with HPAPI linker-payload synthesis experience
- GMP manufacturing and technology transfer to CMOs
- Demonstrated functional representation on a CMC or PDT team
- Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
- People-centered leadership skills in building strong teams through mutual trust and respect and exhibits Amgen leadership attributes of inspire, accelerate, integrate, and adapt
- Proven track record of publications, patents and presentations
What you can expect of usAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.careers.amgen.comIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
SponsorshipSponsorship for this role is not guaranteed.
