Genentech

Principal Systems Engineer

Genentech$103K — $236K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor’s, Master’s, or PhD in chemistry, science, engineering, or related field with relevant years of experience.
  • Hands-on experience with PCR and DNA sequencing methods, including preprocessing techniques.
  • Proficiency in MATLAB, GIT, Python, or similar tools for data analysis and automation.
  • Experience in Design of Experiments methodology and statistical process control.
  • Strong problem-solving skills in fast-paced environments.

Responsibilities

  • Support the feasibility, development, and integration of NGS products.
  • Design and perform wet-lab experiments to enhance the sequencing solution.
  • Interpret experimental results and develop expertise in Single Molecule Sequencing.
  • Maintain concise records of work and progress in the laboratory.
  • Troubleshoot instrument failures and engage with subject matter experts for solutions.

Benefits

  • Comprehensive health and wellness benefits package.
  • Opportunity to work in a pioneering biotechnology environment.
  • Professional development and training opportunities.
  • Collaboration with skilled teams in cutting-edge technologies.
Full Job Description
The Position

Roche Diagnostics develops and produces medical tests and digital tools that provide information to helphealthcare professionals find the right treatment for patients and deliver the best patient care to improve,prolong and save lives.

The Roche Sequencing team is seeking a passionate Systems Integration Engineer/Principal SystemsEngineer to join our Systems Integration Group to support the Next Generation Sequencing (NGS)products. This is a hands-on role; you will be a key contributor in the feasibility, development, and integration phases of end-to-end NGS solutions.

Roche Sequencing Solutions is developing new technologies to make genetic testing easy, reliable, and affordable. As a team member on the Systems Integration team, you will learn to use the Roche Single Molecule Sequencing platform to optimize the final operating protocols while designing & performing wet-lab experiments to further develop the sequencing solution through integration of subcomponents and optimization of the entire system.

  • You will Interpret the experimental results, proper experimental design, and become an expert on Single Molecule Sequencing.

  • You will perform a variety of sample prep, library, or sequencing related experiments & verification studies.

  • You will complete all work using best laboratory practices and maintain a well-organized and concise record of work performed and progress made.

  • You have demonstrated experience for troubleshooting instrument failures with standard root cause methods while engaging with SMEs to understand failure modes.

  • You understand product requirements in order to develop, execute, and document test cases for verification and validation.

This position is located on-site in Santa Clara, CA. This is not a hybrid position.
Relocation benefits will not be provided.

Who You Are:

(Required)

  • You hold a Bachelor27s Degree in chemistry, science, engineering and/or other related field with 7 or more years of experience; or a Master27s degree (in the above listed areas of study) with 5 or more years of experience; or a PhD (in above listed areas of study) with 3+ years of experience.

  • You have demonstrated hands-on experience with PCR, DNA sequencing methods such as raw sample preparation, nucleic acid extraction, library preparation, and NGS sequencing.

  • You have a 5 or more years of experience with MATLAB, GIT, Python or similar tools for data analysis and/or automation; experience with statistical tools (e.g. Python/JMP for regression analysis, ANOVA)

  • You have 7 or more years of experience in Design of Experiments methodology; and application of statistical process control

Preferred:

  • You have a proven track record of leading and performing in a fast-paced, matrix environment; ability to work independently and influencing others with strategic decisions

  • You have experience leading and mentoring others; demonstrated collaborative experience

  • You have experience solving unique or unpredictable problems that might have an impact on the goals and objectives as set by the organization

  • You are adept at planning, prioritizing, multi-tasking, and following through, while remaining highly energetic and focused

  • You have demonstrated interpersonal skills: Strong interpersonal, verbal communication and influencing skills: can influence without authority and has proven experience building and cultivating relationships with key partners and stakeholders, both internally and externally

This position is based onsite in Santa Clara, CA. This is not a hybrid position.

Relocation benefits are not available for this job position.

The expected salary range for this position based on the primary location Santa Clara, CA is $103,600 - $236,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below.



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About Genentech

Genentech is a biotechnology company that develops and manufactures drugs for the treatment of serious medical conditions. The company was founded in 1976 and is headquartered in South San Francisco, California. Genentech's products include treatments for cancer, multiple sclerosis, and other diseases. The company is a subsidiary of Roche, a Swiss pharmaceutical company. Genentech has been recognized for its innovative research and development, and has received numerous awards for its contributions to the biotechnology industry.
Learn more about Genentech
Size
14,000 employees
Industry
Founded
1976

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