Sanofi

Principal Scientist, Systems and Disease Biology

Sanofi$122K — $176K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. in systems/computational biology, biostatistics, or related quantitative field with relevant disease expertise.
  • Minimum of 2 years post-doctoral experience in academia or industry.
  • Hands-on experience with ML/AI and deploying agentic analysis workflows.
  • Proficient in multi-omics and multimodal data analysis, with ability to derive actionable insights.
  • Demonstrated track record of publications or patents indicating productivity and innovation.
  • Strong communication and teamwork skills, with a history of cross-disciplinary collaboration.

Responsibilities

  • Generate disease-related hypotheses using multi-omics and multi-modal data integration.
  • Apply analytical methods to elucidate disease and drug mechanisms.
  • Design workflows to streamline innovative algorithm deployment and computational modeling.
  • Lead projects in experimental design, data analysis, and outsource complex assays.
  • Collaborate with diverse partners on method development and disease studies.
  • Contribute to high-profile presentations and publications.
  • Mentor interns and junior scientists, fostering a collaborative research environment.

Benefits

  • Join a supportive, future-focused team dedicated to scientific advancement.
  • Access numerous growth opportunities for career advancement both domestically and internationally.
  • Receive a comprehensive rewards package to recognize contributions.
  • Enjoy a variety of health and wellness benefits including quality healthcare and 14 weeks parental leave.
  • Engage in pioneering drug development that incorporates patient insights.
  • Contribute to improving global health by accelerating drug development with effective solutions.
  • Work at the forefront of drug discovery utilizing advanced AI and data technologies.
Full Job Description
Job Title: Principal Scientist, Systems and Disease Biology

  • Location: Cambridge, MA


Main Responsibilities:
  • Generating hypotheses on how targets, pathways cell type/state drive diseases (immunology, neurology and oncology disease areas) by integrating multi-omics and multi-modal data, including real-world data and clinical metadata.
  • Applying established analytical methods to understand disease and drug mechanisms.
  • Design intelligent agentic workflows that streamline the deployment of innovative algorithms and computational models.
  • Leading projects involving internal experiment design and data analytics as well as outsourcing of established workflows and/or complex follow-up mechanistic assays (organoid, CRISPR, proteomics)
  • Collaborating with academic, industry, and internal partners on method development and disease-focused scientific studies.
  • Leading and contributing to high-profile presentations and publications.
  • Support the growth of the team by mentoring interns and junior scientists, sharing knowledge and fostering a collaborative research environment.


About You:
  • Ph.D. in systems biology, computational biology, biostatistics, or related quantitative field with proven experience in a relevant disease area (Immunology, Neurology or Oncology) OR PhD in biological sciences, biomedical sciences, immunology, neuroscience, oncology or in a related disease area and proven advanced track record of data analytics, ML/AI, or computational biology.
  • At least 2 years of post-doctoral experience in relevant academic or industry roles.
  • Hands-on experience in ML/AI and building or deploying agentic analysis workflows.
  • Extensive hands-on experience and deep knowledge of multi-omics and/or multimodal data analysis, with ability to extract actionable interpretation and conclusions from the analysis.
  • A track record of productivity, innovation and impact (publications or patents)
  • Excellent communication, organizational, interpersonal and team skills; track record of success working collaboratively across disciplines.


Why Choose Us
  • Bring the miracles of science to life alongside a supportive, future-focused team.
  • Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
  • Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
  • Help improve the lives of millions of people globally by making drug development quicker and more effective.
  • Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.


The salary range for this position is:
$122.250,00 - $176.583,33

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.

About Sanofi

Sanofi is a global pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs and vaccines. The company operates in over 170 countries and has a diverse portfolio of products that includes treatments for diabetes, cancer, cardiovascular disease, and rare diseases. Sanofi is committed to improving global health and has a strong focus on innovation and sustainability. The company has received numerous awards for its research and development efforts and is recognized as a leader in the pharmaceutical industry.
Learn more about Sanofi
Market Cap
$121.6 billion
Industry
Net Income
$12.3 billion
Founded
1990
5 Year Trend
+2.5%
Revenue
$37.3 billion
NASDAQ

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