Principal Scientist, Process Chemistry

Pharmaron

$120K — $170K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Chemistry or related field with 7-15 years of industry experience, or MSc with 11-20 years.
  • Strong background in process chemistry and API development.
  • Expertise in retrosynthetic analysis and advanced laboratory techniques.
  • Experience in regulated environments supporting API drug development.
  • Strong understanding of GLP/GMP principles and regulatory expectations.
  • Proven leadership in scientific initiatives and multidisciplinary collaborations.
  • Strong client-facing and communication skills.

Responsibilities

  • Lead and design experimental programs to tackle chemical development challenges.
  • Apply advanced process chemistry expertise to optimize and support API development.
  • Plan, execute, and document work in compliance with GxP and GMP standards.
  • Mentor junior scientists and lead cross-functional project teams.
  • Manage multiple client projects, ensuring timely delivery of milestones.
  • Support technology transfer and mixed-model projects organization-wide.
  • Foster client relationships and engage in technical discussions on project progress.

Benefits

  • Comprehensive insurance including Medical, Dental & Vision with significant employer contributions.
  • Employer-funded Health Reimbursement Account and Flexible Spending Accounts.
  • 100% Employer-paid Life and AD&D Insurance, Short and Long Term Disability Insurance.
  • Generous 401k plan with employer match.
  • Access to an Employee Assistance Program.
Full Job Description
Position: Principal Scientist - Process Chemistry

Location: Coventry, RI

Salary Range: $120k - $170k

Job Overview:

We are seeking an experienced and collaborative Principal Scientist to lead complex chemical development programs within a fast-paced Process Chemistry environment. This role provides scientific leadership across multidisciplinary project teams, supporting API development for GLP toxicology studies and GMP clinical manufacturing while delivering high-quality solutions to clients.

The successful candidate will combine strong technical expertise in synthetic/process chemistry with leadership, mentoring, and client-facing responsibilities.

Key Responsibilities:
  • Lead and design experimental programs to solve complex chemical development challenges for client projects and internal initiatives.
  • Apply advanced process chemistry and retrosynthetic analysis expertise to support API development and process optimization.
  • Plan, execute, document, and report experimental work in compliance with applicable GxP, ICH, GMP, and company standards.
  • Serve as a scientific leader and mentor to junior scientists and cross-functional project teams.
  • Manage and support multiple client projects, including project leadership, reporting, technical discussions, and delivery of project milestones.
  • Support technology transfer activities and mixed-model projects across the organization.
  • Build strong client relationships, host client visits, and support internal and external audits.
  • Stay current with emerging scientific technologies and apply innovative approaches to process chemistry challenges.
  • Promote a strong quality culture, collaboration, safety, and continuous improvement within the department.
  • Maintain accurate training records and ensure compliance with all safety, procedural, and environmental requirements.

What We are Looking for:
  • PhD in Chemistry or related field with 7-15 years of relevant industry experience OR MSc in Chemistry or related field with 11-20 years of relevant industry experience
  • Strong background in process chemistry, chemical development, and API development within pharmaceutical or biotechnology environments
  • Expertise in retrosynthetic analysis and advanced laboratory techniques supporting process optimization and scale-up activities
  • Demonstrated success solving complex scientific challenges across development programs
  • Experience supporting API drug development within regulated environments
  • Strong understanding of GLP/GMP principles and regulatory expectations preferred
  • Proven ability to lead scientific initiatives and collaborate effectively across multidisciplinary teams
  • Previous mentoring, project leadership, or people leadership experience preferred
  • Strong communication and client-facing skills

Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package:
  • Insurance including Medical, Dental & Vision with significant employer contributions
  • Employer-funded Health Reimbursement Account
  • Healthcare & Dependent Care Flexible Spending Accounts
  • 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance
  • 401k plan with generous employer match
  • Access to an Employee Assistance Program

How to Apply:

Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!

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