Johnson & Johnson

Principal Scientist DDSAI AI/ML

Johnson & Johnson • $117K — $201K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Master's degree in Computer Science, Data Science, Computational Biology, or related field.
  • Proven experience in designing, building, and evaluating AI/ML systems or scientific software.
  • Strong proficiency in Python and scientific computing, with rapid prototyping skills.
  • Hands-on experience with LLM-based systems and frameworks for agent orchestration and evaluation.
  • Ability to work independently and collaboratively in distributed teams using agile methodologies.

Responsibilities

  • Develop and benchmark novel agent architectures and reasoning strategies for scientific research workflows.
  • Prototype agentic capabilities across therapeutic areas, iterating to identify valuable approaches.
  • Collaborate with therapeutic-area researchers to translate domain expertise into agent designs.
  • Publish findings through peer-reviewed papers and demonstrations to enhance J&J's scientific position.
  • Establish patterns and reference implementations for successful innovations transitioning to production.

Benefits

  • Participation in the Company's consolidated retirement plan and 401(k).
  • Eligible for the Company's long-term incentive program.
  • Vacation time of 120 hours per calendar year.
  • Sick time ranging from 40 to 56 hours per calendar year based on location.
  • Parental leave of 480 hours within one year of a child's birth/adoption.
  • Volunteer leave of 32 hours per calendar year.
Full Job Description
Job Function:
Data Analytics & Computational Sciences

Job Sub Function:
Data Science

Job Category:
Scientific/Technology

All Job Posting Locations:
Cambridge, Massachusetts, United States of America, Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

This is a hybrid role available in multiple locations within Raritan, New Jersey; Spring House, Pennsylvania; and Cambridge, Massachusetts. While specific cities are listed in the Locations section for reference, please note that they are examples only and do not limit your application. We invite candidates from various locations to apply and encourage you to review the following states/cities where this opportunity is available:

Raritan, New Jersey

Spring House, Pennsylvania

Cambridge, Massachusetts

An internal pre-identified candidate for consideration has been identified. However, all applications will be considered.

We are searching for the best talent for the Principal Scientist position.

Purpose: Serves as an individual contributor who is a developing subject matter expert in the Data Science field. Develops actionable insights for methods and research for the internal Data Science community. Applies in-depth skills of the field to design and develop industry-leading products. Contributes to scientific projects, programs, and processes of importance to the organization's Data Science function.

Key Responsibilities:

  • Develop and benchmark novel agent architectures, reasoning strategies, and tool-use patterns - determining how LLM-based agents can autonomously plan, hypothesize, and execute within scientific research workflows.
  • Prototype agentic capabilities as proof-of-concepts across therapeutic areas (drug discovery, clinical development, translational science), rapidly iterating to identify which approaches deliver genuine scientific value versus incremental automation.
  • Partner with therapeutic-area researchers to identify high-impact research problems where agentic AI can change what's feasible - translating domain expertise into concrete agent designs and experimental tool integrations.
  • Publish findings through peer-reviewed papers, demonstrations, and knowledge-sharing that advances J&J's scientific position in agentic AI and attract top research talent.
  • Establish the patterns and reference implementations that allow successful innovations to graduate from experimentation into the broader platform - defining what 'ready for production' looks like without owning ongoing operations.


Preferred ("nice-to-have") qualifications:

  • Familiarity with scientific data types, biomedical ontologies, or research workflows in drug discovery, clinical development, or translational science.
  • Experience designing and running benchmarks or evaluation harnesses for AI agent performance in scientific domains.
  • Track record of technical mentorship and cross-team scientific leadership - helping others adopt and extend novel AI capabilities.
  • Experience with cloud-native infrastructure, containerized deployment (e.g., Kubernetes), CI/CD pipelines, and agile development practices - sufficient to move prototypes toward production-ready services.


Qualifications/Requirements:

  • Master's degree or ain Computer Science, Data Science, Computational Biology, or a related discipline.
  • Proven experience designing, building, and evaluating AI/ML systems or scientific software - with a track record of moving from research prototype to demonstrated impact.
  • Strong proficiency in Python and scientific computing; comfort with rapid prototyping, experimental design, and rigorous evaluation of AI capabilities.
  • Hands-on experience with LLM-based systems and frameworks (e.g., LangChain, LangFuse, etc.) used for agent orchestration, tool-calling, prompt engineering, retrieval augmented generation, and/or evaluation frameworks.
  • Ability to work independently and within distributed developer teams utilizing agile programming methodologies
  • Ability to collaborate across disciplines - translating between therapeutic area scientists, data scientists, and engineers to turn domain problems into concrete agentic AI solutions.


Required Skills:

Preferred Skills:
Advanced Analytics, Coaching, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Organizing, Process Improvements, Strategic Thinking, Technical Credibility, Workflow Analysis

The anticipated base pay range for this position is :
$117,000.00 - $201,250.00

Additional Description for Pay Transparency:
Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company's long-term incentive program.
Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:
Vacation -120 hours per calendar year
Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado -48 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year
Holiday pay, including Floating Holidays -13 days per calendar year
Work, Personal and Family Time - up to 40 hours per calendar year
Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child
Bereavement Leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
Caregiver Leave - 80 hours in a 52-week rolling period10 days
Volunteer Leave - 32 hours per calendar year
Military Spouse Time-Off - 80 hours per calendar year

For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

About Johnson & Johnson

Scio Diamond creates single-crystal Type IIa diamonds for the jewelry market and for industrial applications. It employs a patent-protected chemical vapor deposition (CVD) process in a precisely controlled laboratory setting to produce diamonds. It was founded in 2009 and is headquartered in Greenville, South Carolina.

Johnson & Johnson Careers

Joining Johnson & Johnson provides an unparalleled opportunity to be a part of a global team of professionals dedicated to blending care, science, and innovation to profoundly change the trajectory of health for humanity.

Work You’ll Do

At Johnson & Johnson, you will engage in work that matters. Join our community of professionals in health care to drive significant and impactful changes across the globe. Our team at Johnson & Johnson leads with science and heart in sectors from pharmaceuticals to medical devices and consumer health products.

Transform Health Care

Leverage Johnson & Johnson’s culture of innovation to transform health care and improve the lives of people around the world. Our collaborative environment encourages leadership and growth, allowing you to pioneer new strategies for health care solutions with a diverse team of experts.

Innovative Work

Engage in groundbreaking work that enhances how care is delivered on a global scale. Johnson & Johnson’s commitment to innovative health solutions results in dynamic career paths filled with opportunities for professional growth and development.

Be Part of a Great Team

Our team at Johnson & Johnson thrives on collaboration and diversity. You will work alongside over 130,000 employees globally who are committed to making a lasting impact. With a culture that values diversity training and leadership, you are supported in both personal and professional growth.

Future-Proof Your Career

Johnson & Johnson offers a myriad of job opportunities and employment benefits designed to help you meet your career and personal goals. Our employees enjoy comprehensive benefits, including health insurance, retirement plans, and family-friendly policies that pave the way for a fulfilling career and life balance.

Explore Job Opportunities and Internships

Whether you’re looking to start your career or take it to the next level, Johnson & Johnson offers positions ranging from internships to leadership roles across various sectors. Enhance your skills through hands-on experience and our extensive networking and mentorship programs.

Johnson & Johnson Leadership and Development

Our commitment to leadership and continuous learning is at the core of our employment philosophy. Every position offers chances to lead, learn, and innovate. We provide extensive training programs and development courses that prepare you for the future of health care.

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Learn more about Johnson & Johnson
Size
141,700 employees
Market Cap
$462.7 billion
Industry
Net Income
$14.7 billion
Founded
1886
5 Year Trend
+5.5%
Revenue
$82.5 billion
NASDAQ

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