Johnson & Johnson

Principal Scientist, Computational-Immunology Discovery

Johnson & Johnson$115K — $227K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in bioinformatics, Computational Biology, Immunology, Biostatistics, or Computer Science
  • 4+ years of experience in computational biology within immunology or related fields
  • Expertise in analyzing 'omics data, including bulk and single cell RNA-seq
  • Proficient in R and/or Python; cloud computing experience is a plus
  • Strong communication and collaboration skills across disciplines
  • Attention to detail and exceptional scientific rigor
  • Experience with AI-assisted coding or willingness to learn.

Responsibilities

  • Independently build and execute technical plans for multiple programs
  • Deliver timely data analysis, visualization, and interpretation for decision-making
  • Impact Discovery programs through technical execution and team support
  • Collaborate with cross-functional teams to provide computational insights
  • Support program strategy alignment with data-driven findings

Benefits

  • Medical, dental, vision, and life insurance
  • Short- and long-term disability and business accident insurance
  • 401(k) retirement plan and pension participation
  • Generous vacation and sick time allowances
  • Paid holidays including floating holidays
  • Additional personal and family time-off benefits
Full Job Description
Job Function:
Data Analytics & Computational Sciences

Job Sub Function:
Bioinformatics

Job Category:
Scientific/Technology

All Job Posting Locations:
Cambridge, Massachusetts, United States of America, La Jolla, California, United States of America, Spring House, Pennsylvania, United States of America

Job Description:

We are searching for the best talent for a Principal Scientist, Computational-Immunology Discovery, to be in Spring House, PA, La Jolla, CA or Cambridge, MA.

This role is on the Immune Pathway Discovery (IPD) team which is part of Immunology Discovery in the Immunology Therapeutic Area. IPD is responsible for identifying the next wave of transformational therapeutic pathways and applying human 'omics data to advance our Discovery portfolio. We analyze and interpret high-dimensional molecular 'omics data to identify new therapeutic pathways, build disease rationales, and identify patient stratification approaches. IPD supports Discovery projects from inception, through preclinical testing, and up to the transition to clinical trials. We partner closely with biologists to formulate questions, interpret results, and apply the insights we generate to influence the strategic direction of the program. This is an individual contributor role focused on supporting key projects and initiatives with computational analysis.

The successful candidate will have a strong technical background in bioinformatics and established track record of using bioinformatics to drive business impact. Due to the interdisciplinary nature of this role, strong technical, collaboration, communication, and time management skills are critical.

Key Responsibilities:
  • Independently build, align, and execute technical plans to achieve objectives across multiple programs.
  • Timely delivery of hands-on data analysis, visualization, and interpretation for Discovery portfolio decision-making.
  • Substantially impact Discovery programs through direct technical execution and indirect contribution as a member of Discovery project teams.
  • Collaborate with cross-functional teams to drive computational insights for Discovery programs.


Requirements:
  • PhD in a field relevant to bioinformatics including, but not limited to, Computational Biology, Immunology, Biostatistics, or Computer Science.
  • 4+ years work experience using computational biology to discover biological insights from molecular data in immunology or an immunology-related field.
  • Deep technical expertise analyzing 'omics data, including bulk and single cell RNA-seq.
  • Fluent in R and/or Python. Cloud computing experience is a plus.
  • A proven ability to communicate and collaborate across disciplines.
  • Exceptional scientific rigor and attention to detail.
  • Agentic AI and AI-assisted coding experience in an industry setting, or a strong motivation to learn.
  • Preferred experiences:
    • Background in inflammatory diseases, wet lab experience is a plus.
    • Motivation to shape the technical direction of Immune Pathway Discovery by piloting new approaches and demonstrating their potential impact.
    • Expertise in machine learning, data management, spatial transcriptomics, or network biology.
    • Ability to build and leverage a strong scientific network to drive portfolio impact.


The anticipated base pay range for this position is $115,000 to $227,000

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company's long-term incentive program.

Employees are eligible for the following time off benefits:

- Vacation - up to 120 hours per calendar year

- Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year

- Holiday pay, including Floating Holidays - up to 13 days per calendar year

- Work, Personal and Family Time - up to 40 hours per calendar year

Additional information can be found through the link below. For additional general information on company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

#LI-Hybrid

Required Skills:

Preferred Skills:
Advanced Analytics, Analytical Reasoning, Bioinformatics, Coaching, Critical Thinking, Database Structures, Data Privacy Standards, Data Science, Industry Analysis, Interdisciplinary Work, Organizing, Productivity Planning, Quality Standards, Science, Technology, Engineering, and Math (STEM) Application, Scripting Languages, Statistical Computing, Technical Credibility, Technical Writing

The anticipated base pay range for this position is :
$117,000.00 - $201,250.00

Additional Description for Pay Transparency:

About Johnson & Johnson

Scio Diamond creates single-crystal Type IIa diamonds for the jewelry market and for industrial applications. It employs a patent-protected chemical vapor deposition (CVD) process in a precisely controlled laboratory setting to produce diamonds. It was founded in 2009 and is headquartered in Greenville, South Carolina.

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Learn more about Johnson & Johnson
Size
141,700 employees
Market Cap
$462.7 billion
Industry
Net Income
$14.7 billion
Founded
1886
5 Year Trend
+5.5%
Revenue
$82.5 billion
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