Repligen Corporation

Principal Enterprise Architect

Repligen Corporation$156K — $240K *
Enterprise Technology
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Computer Science, Information Systems, Engineering, or related field; Master's preferred.
  • 15-18 years of progressive IT experience; 5 years in enterprise or solution architecture.
  • Proven track record in developing enterprise architecture strategies and governance frameworks.
  • Strong understanding of enterprise architecture methodologies like TOGAF or Zachman.
  • Experience with ERP, CRM, HRIS, and integration technologies.
  • Knowledge of cloud platforms such as Azure, AWS, or Google Cloud.

Responsibilities

  • Define and maintain the enterprise architecture vision and governance standards.
  • Align technology investments with business objectives in partnership with leaders.
  • Develop comprehensive future-state architecture models across key technology domains.
  • Lead architecture reviews for compliance with standards and security policies.
  • Evaluate emerging technologies and propose innovative, value-driven solutions.
  • Establish application portfolio management and reduce technical debt.
  • Define integration strategies and promote scalable patterns across systems.
  • Provide architectural leadership for major transformation initiatives.

Benefits

  • Paid time off
  • Health, dental, and vision insurance
  • Retirement benefits
  • Flexible spending accounts
  • Participation in variable cash programs (bonus or commission)
Full Job Description
The Enterprise Architect Principal (Director) is responsible for defining and governing the organization's technology strategy, enterprise architecture roadmap, and target-state architecture to enable business growth, operational excellence, and digital transformation. This role serves as a strategic bridge between business leadership and technology teams, ensuring that enterprise platforms, applications, data, integrations, infrastructure, and emerging technologies align with business objectives and deliver long-term value.
The Enterprise Architect develops and maintains architecture principles, standards, and governance processes while driving modernization initiatives across enterprise systems such as ERP, CRM, data platforms, integration services, cloud technologies, and AI-enabled solutions. This role collaborates with business stakeholders, solution architects, application owners, and external partners to evaluate technology investments, reduce technical debt, improve interoperability, and establish scalable enterprise capabilities.
The ideal candidate possesses deep experience in enterprise architecture frameworks, business process transformation, cloud technologies, integration strategies, data architecture, and technology governance. They are expected to identify opportunities for innovation, rationalize application portfolios, and guide strategic technology decisions that support organizational objectives. The Enterprise Architect plays a critical role in shaping the future-state technology landscape, ensuring that solutions are secure, scalable, cost-effective, and aligned with the company's long-term business strategy.
Essential Duties and Responsibilities
• Define and maintain the enterprise architecture vision, strategy, roadmap, principles, and governance standards.
• Partner with business and technology leaders to align technology investments with strategic business objectives.
• Develop future-state architecture models covering applications, integrations, data, infrastructure, cloud, and security domains.
• Lead architecture reviews to ensure solutions comply with enterprise standards, scalability requirements, and security policies.
• Evaluate emerging technologies and recommend innovative solutions that drive business value and operational efficiency.
• Establish application portfolio management practices, including technology rationalization and technical debt reduction strategies.
• Define enterprise integration strategies and promote reusable, scalable integration patterns across business systems.
• Provide architectural leadership for major transformation initiatives, including ERP, CRM, AI, analytics, and digital modernization programs.
• Collaborate with cybersecurity, infrastructure, data, and application teams to ensure cohesive enterprise-wide solutions.

Create and maintain architecture artifacts, standards, reference architectures, technology roadmaps, and governance documentation.

Education and/or Work Experience Requirements
• Bachelor's degree in Computer Science, Information Systems, Engineering, or a related technical field; Master's degree preferred.
• Minimum of 15-18 years of progressive IT experience, including at least 5 years in enterprise architecture, solution architecture, or technology leadership roles.
• Proven experience developing enterprise architecture strategies, technology roadmaps, and governance frameworks.
• Strong understanding of enterprise architecture methodologies such as TOGAF, Zachman, or equivalent frameworks.
• Experience with enterprise business applications including ERP, CRM, HRIS, data platforms, and integration technologies.
• Strong knowledge of cloud platforms (Azure, AWS, or Google Cloud), integration architectures, APIs, and data management practices.

The estimated salary range for this role, based in the United States of America is $156,000-$240,000. Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.

About Repligen Corporation

Repligen Corporation is a bioprocessing company headquartered in Waltham, Massachusetts that provides products and services to the biopharmaceutical industry. The company's products are used in the production of monoclonal antibodies, recombinant proteins, and vaccines. Repligen's product portfolio includes chromatography products, filtration products, and protein A ligands. The company also provides bioprocess services, including process development and optimization, analytical testing, and protein characterization. Repligen was founded in 1981 and has grown through a combination of organic growth and acquisitions.
Learn more about Repligen Corporation
Size
1,852 employees
Market Cap
$9.5 billion
Industry
Net Income
$59.9 million
5 Year Trend
+45%
Revenue
$366.2 million
NASDAQ

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