Post Doctoral Fellow, Metabolic & Rare Disease Research Laboratory

Children's Hospital of Orange County

$67K — $111K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Doctorate Degree in relevant field
  • Strong critical thinking skills
  • Ability to manage multiple assignments
  • Excellent written communication skills
  • Detail-oriented with accurate information recall

Responsibilities

  • Lead preclinical research in rare pediatric diseases
  • Conduct advanced animal studies and biochemical analyses
  • Develop innovative preclinical models for therapeutic strategies
  • Collaborate with interdisciplinary teams on research projects
  • Contribute to NIH- and foundation-funded research programs

Benefits

  • Mentorship from a nationally recognized research leader
  • Opportunity to work on cutting-edge research
  • Engagement in impactful pediatric research
  • Career advancement opportunities in translational research
Full Job Description
Work Location
Orange, California

Work Shift
Day - 08hrs (United States of America)

Job Summary
The Post Doctoral Fellow for all levels possesses, understands, and applies a comprehensive knowledge in area of specialization. Develops understanding and skills to allow for completion of assignments that cross fields of specialization. Develops leadership and management skills.

Pay Range
Minimum $67,579 Midpoint $89,544 Maximum $111,488

Rate of pay is determined by various factors, including but not limited to knowledge, skills, competencies, experience, education, as well as position requirements.

We are seeking a highly motivated Postdoctoral Research Fellow to join the CHOC Metabolic and Rare Disease Research Laboratory. This fellowship offers an exceptional opportunity to lead and contribute to cutting-edge preclinical research focused on therapeutic discovery and validation for rare pediatric diseases. The Postdoctoral Fellow will play a key role in advancing complex animal studies, biochemical analyses, histopathology, and therapeutic development.Our laboratory is dedicated to investigating pediatric metabolic and genetic disorders, with a primary focus on lysosomal storage diseases (LSDs) such as mucopolysaccharidosis (MPS), Pompe disease, and Batten disease. Under the mentorship of a nationally recognized research leader, our team bridges basic science with clinical applications, emphasizing gene therapy, genome editing, and the creation of innovative preclinical models to explore emerging therapeutic strategies for these devastating conditions.

This fellowship is ideal for a driven, curious, and collaborative scientist eager to deepen their expertise in translational research. The ideal candidate will be independent, well-organized, and proactive, with strong problem-solving skills and the ability to thrive in a fast-paced, high-impact research environment. If you are passionate about advancing innovative pediatric research and helping bring transformative therapies from the laboratory to clinical care, this position provides a unique opportunity to make a meaningful and lasting impact. The Postdoctoral Research Fellow will contribute significantly to NIH- and foundation-funded research programs while supporting our mission to improve the lives of children affected by rare genetic diseases.

Experience:

Required : None

Education:

Required: Doctorate Degree

Specialized Skills:

Required: Able to think critically; work independently; manage multiple assignments; compose written material; work well under pressure; problem solve; organize and prioritize workload; recall information with accuracy; pay close attention to detail. Able to relate and communicate positively, effectively, and professionally with others; provide leadership; be assertive and consistent in enforcing policies; work calmly and respond courteously when under pressure; lead, supervise, teach, and collaborate; accept direction.

Work Environments - Functional Demand:
Light - Moderate energy level Lift and carry 25-35 lbs. Push/pull 50-100 lbs. (ie. empty bed, stretcher).

Physical Activity Requirements:
Bending, Carry Objects, Climbing, Keyboard use/repetitive motion, Pinching/fine motor activities, Push/Pull, Reaching forward, Reaching overhead, Sitting, Squat/kneel/crawl (Squad & Knee), Standing, Talk or hear, Taste or smell, Twisting, Walking, Wrist position deviation

Physical Activity Lifting
Lifting (Floor to waist level) - Constant 67 or more%, Lifting (Floor to waist level) - Frequent 36-66%, Lifting (Floor to waist level) - Occasional 0-35%, Lifting (Waist level and above) - Constant 67 or more%, Lifting (Waist level and above) - Frequent 36-66%, Lifting (Waist level and above) - Occasional 0-35%

Sensory Requirements:
Color Discrimination, Depth Perception, Far Vision, Hearing, Near Vision

Environment Requirements:
Airborn Communicable Disease, Bloodborne Pathogens, Chemical, Dust Particular Matter, Extreme Noise Levels, Extreme Temperatures, Radiation, Uneven Surfaces or Elevations

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