Pharma In Vivo Biologist

Cogent Scientific

$95K — $115K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • BS in Molecular Biology, Cell Biology, or related field with 5 years of lab experience, or MS with 2-3 years of lab experience.
  • Extensive in vivo pharmacology skills, preferably in oncology.
  • Preferred experience with IVIS imaging.
  • Proficiency in Graphpad Prism is preferred.
  • Strong verbal and written communication skills.
  • Ability to work effectively as part of a team and independently.

Responsibilities

  • Design and execute in vivo studies in partnership with pre-clinical discovery and translational biology teams.
  • Collaborate with various discovery technologies to create and implement innovative in vivo models.
  • Prepare drug solutions and administer through multiple routes including subcutaneous, tail vein, intraperitoneal, and oral gavage.
  • Perform tumor cell implantation and measure tumor size with calipers, preferably through orthotopic implantation.
  • Harvest samples from mice including blood, tumor, bone marrow, and spleen for PK/PD and toxicity assessments, as well as flow cytometry and histology analysis.
  • Culture tumor cells in compliance with standard operating procedures (SOPs) and assist in developing SOPs.

Benefits

  • Day shift position, approximately 8 am to 5 pm local time.
Full Job Description
We currently have a role available for an Pharma In Vivo Biologist.

Job duties include, but are not limited to, the following:

  • Design and execute in vivo studies with pre-clinical discovery and translational biology teams.
  • Interact and collaborate with various discovery technologies functional teams to develop and implement novel in vivo models.
  • Prepare drug solutions and inoculations, multiple routes of drug administration (e.g. subcutaneous, tail vein, intraperitoneal, and retro-orbital injection and oral gavage).
  • Tumor cell implantation and tumor measurement using a caliper.
    • Orthotopic implantation is preferred.
  • Harvest blood, tumor, bone marrow, spleen and other tissue samples from mice to help establish PK/PD and toxicity measurements, flow cytometry analysis and histology.
  • Culture tumor cells according to SOPs and contribute to the development of SOPs.


Job requirements include, but are not limited to:

  • BS - Molecular Biology, Cell Biology or related field with 5 years of related lab experience experience or MS wiith 2-3 years of related lab experience required.
  • Extensive expertise in vivo pharmacology skills preferably in oncology.
    • Experience in IVIS imaging is preferred but not required.
  • Proficiency in Graphpad Prism is preferred.
  • Excellent communication skills - verbal and written.
  • Works well both as a team and as an individual.
  • Demonstration of excellent team player skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions. The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.


This is a day shift position (approx. 8a-5p local time).

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