Member of Technical Staff, Epigenetics

LatchBio

$180K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • 5+ years hands-on experience with epigenetics or epigenomics data
  • Prior contribution to a novel epigenomics method, tool, or published pipeline
  • Proficiency in Python and/or R

Responsibilities

  • Design the technical approach for teaching AI agents to interpret complex epigenomics data
  • Map out end-to-end data analysis workflows from instrument outputs to scientific decisions
  • Lead a team of engineers and biologists to build datasets for effective AI training
  • Oversee the analysis of critical processes like sequencing QC, alignment, and peak calling
  • Guide efforts in chromatin accessibility analysis, TF footprinting, and motif analysis

Benefits

  • 100% premium covered Blue Shield platinum health plan with no deductible or out-of-pocket costs
  • Free meals provided for lunch and dinner
  • Work in a waterfront office in China Basin, San Francisco
Full Job Description
We're seeking a Member of Technical Staff for Epigenetics to lead our epigenomics bench, pushing its capabilities to the frontier of what artificial intelligence can achieve in biology.

About the Role

You will design our technical approach to teaching agents how to understand and handle complex epigenomics data, mapping out end-to-end data analysis workflows and working from instrument outputs to real scientific decisions.

You will lead a team of software engineers and biologists building datasets to teach these agents to reason better across:
  • Sequencing QC → alignment & peak calling
  • Chromatin accessibility analysis
  • TF footprinting & motif analysis
  • Histone modification → single-cell multiome integration
  • Gene regulatory network construction

Requirements
  • 5+ years hands-on experience with epigenetics or epigenomics data
  • Prior contribution to a novel epigenomics method, tool, or published pipeline
  • Proficiency in Python and/or R

Compensation & Logistics
  • $180k+ base, increasing with technical depth and experience
  • Variable compensation + equity + stock options
  • 100% premium covered Blue Shield platinum health plan ($0 deductible / $0 out-of-pocket)
  • Free meals (lunch and dinner)
  • Waterfront office in China Basin, San Francisco
  • Full-time, in-person

Location: San Francisco, CA. In-person.

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