Regeneron Pharmaceuticals, Inc

Manager, Statistical Genetics

Regeneron Pharmaceuticals, Inc • $128K — $210K *
Tarrytown, NY 10591In-Person
Pharmaceuticals & Biotech
Less than 5 years of experience
4 days ago
Be an Early Applicant
Job Overview by Ladders

Qualifications

  • PhD with at least 3+ years of relevant experience
  • Expertise in large-scale genetic association analyses
  • Proficiency in multi-omic data integration
  • Experience with immunologic datasets preferred
  • Strong programming skills in Python, R, C/C++, Bash, and/or Julia
  • Demonstrated ability to manage research projects independently
  • Strong quantitative skills with experience in advanced statistical techniques.

Responsibilities

  • Conduct genetic association analyses including GWAS and rare variant analysis
  • Integrate genetic data with multi-omic datasets for target discovery
  • Develop methods for data harmonization across datasets
  • Apply functional genomic data to prioritize genetic variants
  • Ensure quality control on large genetic and phenotypic datasets
  • Identify data-driven hypotheses for translational genetics
  • Execute analytic studies from conception to completion
  • Collaborate with interdisciplinary teams across R&D functions.

Benefits

  • Comprehensive health and wellness programs, including medical and dental insurance
  • 401(k) with company match
  • Family support benefits and equity awards
  • Annual bonuses and generous paid time off
  • Paid leave options including military and parental leave
  • Access to fitness centers
  • Inclusive culture promoting teamwork and collaboration.
Full Job Description

This individual contributor role is responsible for conducting analyses of large-scale human genetic and phenotypic datasets for the discovery and validation of new therapeutic targets at the Regeneron Genetics Center (RGC). Work draws on both in-house and public data resources, integrating genetic data with multi-omics datasets and applying state-of-the-art statistical methodologies across analytic and translational genetics. The role collaborates closely with pre-clinical and clinical development teams colleagues across Regeneron’s R&D functions.

In this role, a typical day might include the following:

  • Conduct genetic association analyses using large-scale human genetic data, including genome-wide association analysis (GWAS), exome-wide association analysis (EXWAS), rare variant analysis, Mendelian randomization, LD Score regression, polygenic risk score modeling, pleiotropy analysis, and meta-analysis.

  • Integrate genetic data with multi-omic datasets to support therapeutic target discovery and validation.

  • Develop and implement methods for data harmonization and normalization across in-house and public data resources.

  • Apply functional genomic data to prioritize variants and genes of interest.

  • Perform quality control on large-scale genetic and phenotypic datasets.

  • Identify and interrogate data-driven hypotheses as part of analytic and translational genetics work.

  • Design and independently execute analytic studies from conception to completion.

  • Collaborate with groups across Regeneron’s R&D functions, including pre-clinical and clinical development teams, to advance therapeutic programs.

This role might be for you if you have:

  • Experience developing and implementing data harmonization and normalization methods

  • Experience with genetic analysis approaches including GWAS, EXWAS, rare variant analysis, Mendelian randomization, LD Score regression, polygenic risk score modeling, pleiotropy analysis, meta-analysis, and use of functional data to prioritize variants and genes

  • Ability to independently lead and manage research projects from conception to completion

  • Strong communication and collaboration skills; proven track record of effective work in interdisciplinary teams

  • Outstanding ability to summarize and present human genetic study results to diverse technical audiences, from statistical genetics specialists to biologists, drug designers, and clinicians

  • Strong programming skills in languages such as Python, R, C/C++, Bash, and/or Julia.

  • Strong quantitative skills, including applied statistical techniques such as regression and classification, Bayesian inference, and hypothesis testing. Experience with analytic and visualization tools including Git/Github, Claude, Adobe, Docker

To be considered for this role, we require:

  • PhD with at least 3+ years of relevant experience

  • Expertise in genetic association analyses using large-scale genetic data

  • Proficiency in multi-omic data integration for therapeutic target discovery

  • Experience working with immunologic datasets and/or experience with immunology is preferred

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location.  In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/.  For other countries’ specific benefits, please speak to your recruiter.
Please be advised that at Regeneron, we believe we are most successful and work best when we are together.  For that reason, many of Regeneron’s roles are required to be performed on-site.  Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location.

Salary Range (annually)

$128,600.00 - $210,000.00

About Regeneron Pharmaceuticals, Inc

Regeneron Pharmaceuticals is a biopharmaceutical company that discovers, develops, and commercializes pharmaceutical products for the treatment of serious medical conditions. The Company has therapeutic candidates in clinical trials for the potential treatment of cancer, eye diseases, and inflammatory diseases, and has preclinical programs in other diseases and disorders. The company’s product portfolio includes EYLEA, an aflibercept injection; ARCALYST, a rilonacept Injection for subcutaneous use; ZALTRAP for metastatic colorectal cancer; trap fusion proteins; and fully human monoclonal antibodies. On March 26, 2012, it was announced that Sanofi and Regeneron are in development with a new cholesterol drug which will help reduce cholesterol up to 72%. Regeneron Pharmaceuticals was founded in 1988 and is currently headquartered in New York, USA.

Regeneron Pharmaceuticals, Inc Careers

Join the innovative team at Regeneron Pharmaceuticals, Inc, a leading biotechnology company renowned for its commitment to science-driven solutions. This is an unparalleled opportunity to advance your career with a company at the forefront of medical breakthroughs and clinical research.

Work You’ll Do

At Regeneron Pharmaceuticals, Inc, you will collaborate with some of the brightest minds in the industry, engaging in work that directly contributes to the health and well-being of populations globally. Our diverse team of professionals is dedicated to pioneering developments in biotechnology through continuous innovation and rigorous research.

Explore Job Opportunities and Growth

Regeneron offers a variety of job opportunities that encourage professional growth and personal achievement. Whether you're seeking an entry-level position or a more senior role, you will find a path that aligns with your career ambitions and skills. Our supportive culture emphasizes leadership development and diversity training, ensuring every team member can thrive.

Internship Programs

Kickstart your career with a Regeneron internship. Our programs provide invaluable industry experience, mentoring from seasoned professionals, and opportunities to develop skills that are crucial in the biotech field. Interns at Regeneron gain hands-on experience, contributing to projects that matter.

Benefits and Culture

Choosing to work at Regeneron Pharmaceuticals, Inc means choosing a career that comes with competitive benefits designed to support you both professionally and personally. We offer comprehensive health benefits, retirement plans, and wellness programs. Our inclusive culture fosters an environment where every employee can flourish, driven by collaboration and mutual respect.

Innovation and Leadership

Lead the way in biotechnological innovation with Regeneron. Our leadership is constantly looking towards the future, investing in cutting-edge technology and research that pave the way for medical advancements. At Regeneron, leadership and innovation go hand in hand, creating a dynamic where breakthroughs are common.

Networking and Professional Development

Enhance your professional network and skill set through Regeneron’s extensive networking opportunities and ongoing professional development programs. We believe in nurturing our talent with advanced training sessions and regular workshops that cover the latest trends and technologies in the biotech industry.

Join Our Team

Discover the impact you can make in a career at Regeneron Pharmaceuticals, Inc. Search for open positions that match your skills and interests. We are continuously hiring and looking for passionate, curious, and innovative team players.

Stay Connected

Keep up to date with the latest at Regeneron by following our careers blog. Gain insights from the experts and learn more about the exciting world of biotech at Regeneron Pharmaceuticals, Inc.

Prepare for Your Interview

Ready to join us? Prepare your resume and refine your interview skills to become part of a company that’s dedicated to changing lives. Personalize your job search and get tailored job alerts directly to your inbox, so you never miss an opportunity to be part of our team. At Regeneron Pharmaceuticals, Inc, your career is poised for tremendous growth and innovation. Explore the opportunities today and be part of a team that’s shaping the future of biotechnology.
Learn more about Regeneron Pharmaceuticals, Inc
Size
10,368 employees
Market Cap
$78.1 billion
Industry
Pharmaceuticals & Biotech
Net Income
$3.5 billion
Founded
1988
5 Year Trend
+27%
Revenue
$8.4 billion
NASDAQ
REGN
* Ladders Estimates

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