AstraZeneca

Manager Site Operations, Facilities Maintenance, Second shift

AstraZeneca$89K — $134K *
Real Estate & Construction
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 5-7 years of maintenance leadership in cGMP infrastructure
  • Expertise in utilities, BMS monitoring, CMMS (SAP)
  • Experience in managing capital projects and vendor contracts
  • Strong compliance knowledge in cGxP/FDA standards
  • Proven skills in root cause analyses and team development

Responsibilities

  • Maintain campus-critical systems through preventive, predictive, and corrective maintenance
  • Optimize preventive maintenance programs and track key performance indicators
  • Collaborate on accurate work management via Planning and Scheduling
  • Define stocking strategies for materials and spare parts
  • Lead facilities capital projects from planning through completion
  • Oversee construction and commissioning processes for safety and communication
  • Manage vendor relationships to ensure quality and cost-effectiveness
  • Ensure compliance with cGxP/FDA regulations and conduct safety training

Benefits

  • Retirement programs
  • Paid time off including vacation and holiday leave
  • Health, dental, and vision insurance coverage
  • Opportunities for short-term incentive bonuses and equity-based awards
Full Job Description
Join a collaborative, tech-enabled team using data, analytics, and current engineering to boost asset performance and sustainability. You'll turn metrics into action, lead a high-performing team, and deliver projects that strengthen infrastructure and reduce environmental impact-shift after shift.

What you'll do:
  • Facilities and utilities: Keep campus-critical systems running through preventive, predictive, and corrective maintenance; ensure uninterrupted utilities for cGMP operations and respond to BMS alarms 24/7.
  • Maintenance excellence: Build and optimize PM programs, follow KPIs, and lift uptime and asset health.
  • Work management: Partner with Planning and Scheduling; drive accurate CMMS (SAP) data and effective work execution.
  • Materials and spares: Set stocking and reordering strategies to protect reliability.
  • Projects: Lead facilities capital projects from plan to handover-on scope, budget, schedule, and sustainability targets.
  • Construction and commissioning: Oversee reviews, permitting, commissioning, and collaborator communications for safe, smooth delivery.
  • Vendors and contracts: Source, debate, and lead to quality and value.
  • Compliance and quality: Ensure cGxP/FDA/SOP adherence; handle changes, deviations, and training/qualification.
  • Investigations and safety: Lead root cause analyses; champion SHE, hazard assessments, training, and PPE.
  • Sustainability and CI: Cut carbon, waste, and cost; optimize energy and resources with partner teams.
  • People leadership: Coach technicians, engineers, and contractors; build capability and strong cross-functional ties.
  • Site stewardship: Contribute to site planning, procedures, budgets, schedules, and performance metrics; brief senior stakeholders.


Minimum requirements:
  • Bachelor's in Engineering, Facilities Management, or a related technical discipline. Equivalent work experience (5 years) may be considered.
  • 5+ years of experience in Maintenance, Engineering, or Facilities Management.
  • Experience with maintenance software, AutoCAD, and other specialized programs used in operations.
  • Maintenance leadership on sophisticated, cGMP-related infrastructure with 24/7 reliability expectations.
  • Strength in utilities, BMS monitoring, CMMS (SAP), planning/scheduling, and KPI-driven improvement.
  • Experience delivering facilities capital projects and managing vendors/contracts.
  • Proven safety, cGxP/FDA compliance, and quality systems ownership.
  • Track record in investigations (RCA/CAPA) and team development.
  • Strategic influence across departments with budget, schedule, and policy accountability.


Desirable skills:
  • cGMP lab/pilot plant/manufacturing experience; second-shift or 24/7 leadership.
  • Certifications (PMP, CMRP), Lean/Six Sigma, and energy/sustainability (LEED, ISO 14001).
  • Analytics for BMS/CMMS to enable predictive maintenance and asset health.
  • Managing multi-contractor environments and long-term service agreements.


The annual base pay (or hourly rate of compensation) for this position ranges from $89,874.40 - $134,811.60. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Ready to lead? If you're excited to run second-shift operations that keep mission-critical facilities safe, compliant, and always on-and to turn metrics into meaningful progress-apply now.

Date Posted
16-Jun-2026

Closing Date
29-Jun-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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