Pfizer

Manager, Clinical Pharmacology

Pfizer$106K — $176K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Pharmacokinetics, Clinical Pharmacology, Pharmacometrics, Engineering or PharmD
  • Strong written and verbal communication skills
  • Experience interpreting PK and PK/PD data
  • Hands-on experience with software tools for PK and PK/PD analyses (e.g., R, NONMEM, Monolix)

Responsibilities

  • Act as Clinical Pharmacology representative on Clinical Sub Team and Development Team.
  • Provide clinical pharmacology components to Clinical Study Protocols and Reports.
  • Offer expertise to oncology project teams in clinical pharmacology studies.
  • Implement model-based drug development using quantitative approaches.
  • Conduct non-compartmental analysis of PK data and relevant PK/PD analyses.
  • Plan and execute PK/PD analyses and optimize dosing regimens.
  • Provide recommendations for clinical doses and integrate regulatory documentation.

Benefits

  • Relocation support available
  • Flexible work location with hybrid arrangement
  • Comprehensive health benefits including medical, dental, and vision
  • 401(k) plan with matching contributions and additional retirement savings contribution
  • Paid vacation, holiday, personal days, caregiver/parental and medical leave
Full Job Description

ROLE SUMMARY

Will join a team of scientists supporting oncology development programs. Will be the Clinical Pharmacology Lead providing clinical pharmacology expertise to a multidisciplinary project team of an oncology program.

ROLE RESPONSIBILITIES

  • Acts as Clinical Pharmacology representative on Clinical Sub Team and Development Team, as appropriate.
  • Provides the clinical pharmacology components to Clinical Study Protocols, Clinical Study Reports, Clinical Pharmacology plans for programs.
  • Provides clinical pharmacology expertise to oncology project teams including planning, design, and oversight of clinical pharmacology studies with operational assistance from clinical operations colleagues.
  • Participates in implementing model-based drug development using quantitative approaches to address scientific questions arising during drug development.
  • Provides non-compartmental analysis of PK data and executes appropriate PK/PD analyses such as population PK modeling, PK/PD modeling and conducting simulations.
  • Plans relevant PK/PD analyses. Is responsible for integrating knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses and dosage regimens throughout clinical drug development in collaboration with pharmacometrics and statistics groups (as relevant).
  • Provides recommendations for clinical doses and dosing regimens (including drug-drug interactions, food effect, special group dosing) to the Clinical and Development teams and in regulatory documentation.
  • Responsible for clinical pharmacology contributions to all regulatory documents including Investigator Brochures, EOP2 meetings.
  • Supports the resolution of clinical pharmacology queries from drug regulatory agencies, takes a lead role in writing and reviewing responses to regulatory queries.
  • Work in a matrix environment with a cross-functional clinical team.

BASIC QUALIFICATIONS

  • PhD in Pharmacokinetics, Clinical Pharmacology, Pharmacometrics, Engineering or PharmD
  • Strong written and verbal communication skills

PREFERRED QUALIFICATIONS

  • Experience interpreting PK and PK/PD data and integrating this knowledge into the clinical trial and overall clinical program.
  • Hands-on experience with common software tools for PK and PK/PD analyses (e.g., R, NONMEM, Monolix)


Relocation support available

Work Location Assignment: Flexible


Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.

The annual base salary for this position ranges from $106,000.00 to $176,600.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Medical

About Pfizer

Hospira, Inc. is the provider of injectable drugs and infusion technologies. Through its broad, integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees.

Pfizer Careers

Joining Pfizer’s global team offers more than just job opportunities; it’s a chance to be a part of a company that leads with science and innovates for better health. As a leading biopharmaceutical company, Pfizer is at the forefront of transforming lives through innovation, leadership, and diversity. Work You’ll Do At Pfizer, you will collaborate with some of the brightest minds in the industry, engaging in work that enhances global health and saves lives. Our culture thrives on intellectual curiosity, professional growth, and inclusivity, making every day a learning opportunity. Here, your skills will be honed, your professional acumen will be expanded, and you will be part of a team that values the power of diverse insights to drive success. Pfizer’s Leadership and Growth Lead and innovate with Pfizer, where we value the growth of each employee. Our leadership is committed to providing employees with the training and resources needed to excel in their careers. Pfizer offers a variety of career paths, including roles in research, marketing, finance, technology, and more, each offering a unique blend of challenges and rewards. Internship and Employment Opportunities Start your career with Pfizer through our internship programs or dive straight into a full-time position. We are hiring individuals who are passionate about healthcare and who seek to make a difference in the world. Our internships provide invaluable industry experience, networking opportunities, and a potential pathway to full-time employment. Benefits and Culture Pfizer is dedicated to fostering a workplace where all employees feel valued and can achieve their full potential. We offer competitive benefits packages that support the health, well-being, and financial security of our employees and their families. At Pfizer, you’ll find a culture that encourages collaboration, innovation, and continuous learning. Join Our Team Explore the numerous job opportunities at Pfizer by searching open positions that match your skills and interests. We look for driven, curious, and innovative team players who are ready to advance their careers in a transformative company. Stay Connected Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await at Pfizer. Interview and Resume Tips Prepare for your future with Pfizer by utilizing our resources for resume building and interview preparation. We provide guidance on how to effectively showcase your skills and experiences to align with the needs of a position at Pfizer. Our goal is to help you succeed in securing a role that suits your professional goals and personal growth aspirations. Pfizer: A Place Where You Can Make a Difference Every position at Pfizer contributes to our mission of making the world a healthier place. Whether through direct patient care, research innovation, or corporate roles that support our operations, your work will have global impact. Join us in our journey to change lives—explore Pfizer careers today.
Learn more about Pfizer
Size
79,000 employees
Market Cap
$285.9 billion
Industry
Net Income
$9.6 billion
Founded
1849
5 Year Trend
+9%
Revenue
$41.9 billion
NASDAQ

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