Astellas Pharma US, Inc

Lead, Innate Immunity Cancer Cell Death Biology

Astellas Pharma US, Inc$145K — $207K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • PhD, MD, or equivalent degree in pharmacology, oncology, immunology, or related field.
  • Approximately 8+ years of experience in pharmaceutical or biotech drug discovery.
  • Hands-on experience in antibody and ADC research.
  • Experience leading antibody and/or ADC projects as a project leader.
  • Prior people management or team leadership experience.
  • Solid understanding of pharmacology, including in vitro and in vivo evaluation and mechanisms of action.
  • Experience working in cross-functional teams.

Responsibilities

  • Provide scientific input and review for multiple ADC discovery projects from pharmacology and biology perspectives.
  • Collaborate with project leads to support study design, data interpretation, and decision-making.
  • Apply prior experience in ADC and antibody research to improve overall project quality and execution.
  • Contribute to new project ideation by assessing feasibility and scientific rationale.
  • Line-manage scientists, including day-to-day supervision, coaching, and performance management.
  • Support team members' development and optimize role assignments based on strengths.
  • Promote effective collaboration with cross-functional partners (e.g., chemistry, biologics, DMPK).

Benefits

  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Company fleet vehicle for eligible positions
  • Referral bonus program
Full Job Description
Lead, Innate Immunity Cancer Cell Death Biology

Purpose & Scope

This position supports antibody-drug conjugate (ADC) research in oncology by contributing to multiple discovery programs while managing and developing a team of scientists. Reporting to the Head of Innate Immunity & Cancer Cell Death Biology, the People Manager will balance project support with people management to enhance the quality and efficiency of ADC research. The role also serves as a key support to the Head by providing practical scientific and operational input into research direction and new project opportunities.

Role and Responsibilities

Scientific Contribution
  • Provide scientific input and review for multiple ADC discovery projects from pharmacology and biology perspectives
  • Collaborate with project leads to support study design, data interpretation, and decision-making
  • Apply prior experience in ADC and antibody research to improve overall project quality and execution
  • Contribute to new project ideation by assessing feasibility and scientific rationale

People Management
  • Line-manage scientists, including day-to-day supervision, coaching, and performance management
  • Support team members' development and optimize role assignments based on strengths
  • Foster a collaborative and open team environment to enhance communication and productivity

Operational Support
  • Support the Head of Innate Immunity & Cancer Cell Death Biology in research and team operations
  • Ensure appropriate communication of project progress and challenges to facilitate decision-making
  • Promote effective collaboration with cross-functional partners (e.g., chemistry, biologics, DMPK)


Required Qualifications
  • PhD, MD, or equivalent degree in pharmacology, oncology, immunology, or related life science field
  • Approximately 8+ years of experience in pharmaceutical or biotech drug discovery
  • Hands-on experience in antibody and ADC research
  • Experience leading antibody and/or ADC projects as a project leader
  • Prior people management or team leadership experience
  • Solid understanding of pharmacology, including in vitro and in vivo evaluation and mechanism of action
  • Experience working in cross-functional teams

Preferred Qualifications
  • Player-coach mindset with the ability to contribute scientifically while managing a team
  • Strong collaborative and problem-solving skills
  • Proactive, flexible, and able to work effectively in a dynamic environment
  • High integrity and strong sense of accountability
  • Author of over 8 peer-reviewed publications in biology


Location and Working Environment
  • This position is based in South San Francisco and will require on-site work/management in principle.
  • Participation in meetings scheduled for early mornings and late nights is regularly required.


Salary Range

$145,460-$207,800 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations)

Benefits:
  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Company fleet vehicle for eligible positions
  • Referral bonus program


#LI-TR1

About Astellas Pharma US, Inc

Astellas Pharma US, Inc is a pharmaceutical company that develops and markets drugs for the treatment of cancer, immunology, and urology. The company is a subsidiary of Astellas Pharma Inc, a Japanese pharmaceutical company. Astellas Pharma US, Inc was founded in 2005 and is headquartered in Northbrook, Illinois. The company has over 17,000 employees and operates in over 50 countries. Astellas Pharma US, Inc is committed to improving the health and well-being of patients through the development of innovative and effective therapies.
Learn more about Astellas Pharma US, Inc
Size
14,522 employees
Industry
Founded
2005
NASDAQ

Similar Jobs

More Jobs at Astellas Pharma US, Inc

More Pharmaceuticals & Biotech Jobs

Find similar Lead, Innate Immunity Cancer Cell Death Biology jobs: