Head of Medicinal Chemistry

Allorion Therapeutics

• $160K — $200K *
Pharmaceuticals & Biotech
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • PhD with a strong chemistry research background
  • 15+ years of industry experience including 5+ years leading a medicinal chemistry group
  • Proven track record of delivering clinical candidates in line with timelines
  • Exceptional organizational skills with the ability to juggle multiple projects
  • Experience thriving in small to medium-sized biotech environments
  • Excellent interpersonal skills with a collaborative mindset

Responsibilities

  • Lead the medicinal chemistry team across various projects
  • Oversee programs leading up to IND-enabling studies, including drug design
  • Provide scientific direction and leadership for chemistry activities
  • Collaborate across departments to ensure timely compound delivery
  • Offer strategic insights for discussions with Allorion's management
  • Manage synthetic chemistry operations both in-house and at CROs

Benefits

  • Dynamic and interdisciplinary work environment
  • Opportunity to impact the development of new therapeutics
  • Key member of the leadership team
  • Room for collaboration across multiple scientific disciplines
  • Engagement with a small to medium-sized company culture
Full Job Description
Natick, Massachusetts

Position closed

Allorion Therapeutics is seeking a highly motivated and experienced leader as Head of Medicinal Chemistry to lead medicinal chemistry team within a dynamic and interdisciplinary team of junior or senior scientists to develop new therapeutics for unmet medical needs. The successful candidate will be a key member of the Allorion leadership team and responsible for ensuring the strategic planning and execution of clinical development within timelines and budgets and with high qualities.

Responsibilities

  • Lead Allorion medicinal chemistry team across multiple programs
  • Overview all programs up to IND-enabling studies, including structure-based drug design
  • Provide scientific direction, leadership and solution for medicinal chemistry and synthetic
    chemistry activities of Allorion
  • Work across a matrixed organization with Discovery Biology, Translational Medicine,
    DMPK/clinic pharm, Tox, and CMC to deliver the candidate compound within a suitable timeline
  • Provide strategic perspective and guidance to Allorion's R&D for discussions and decisions with
    Allorion management team
  • Overview synthetic chemistry activities at in-house and Contract Research Organizations (CROs)


Required Skills

  • PhD with strong chemistry research background
  • 15+ years of industry experience with 5+ years in leading medicinal chemistry group, with
    demonstrated track records in delivering clinical candidates within a suitable timeline and
    resource
  • Able to provide leadership on a medicinal chemistry team and cross-functional team
  • Strong organizational skills and the ability to manage multiple tasks
  • Ability to thrive in the highly entrepreneurial biotech environment, with experience in a
    small/medium size company
  • Excellent interpersonal skills and mindset of collaboration and teamwork, and the ability to
    function in a highly matrixed organization


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