Description
Global Trials Optimization Specialist / Project Manager I (Sponsor Dedicated/Remote - US only)

Job Responsibilities

Global Trials Optimization Specialist

Sponsor Dedicated/ Remote - US only

Help Shape the Success of Global Clinical Trials

Are you energized by using data, strategic planning, and cross-functional collaboration to help clinical trials achieve enrollment success? We're seeking a Global Trials Optimization Specialist to support program feasibility, recruitment and retention strategy, and in-life trial optimization across global clinical studies within General Medicine, Dermatology, Rheumatology, Infectious Disease, and Vaccine programs.

In this role, you'll transform trial goals, country insights, enrollment analytics, and feasibility data into actionable strategies that drive study performance. Working closely with clinical trial teams, country stakeholders, vendors, legal partners, and analytics teams, you'll help identify enrollment opportunities, mitigate risks, and support effective patient and site engagement initiatives.

This is an outstanding opportunity for a clinical research professional who enjoys blending clinical operations, feasibility strategy, patient recruitment, stakeholder management, and data-driven decision-making to improve clinical trial outcomes on a global scale.

What You'll Do

Program Feasibility and Trial Optimization

• Gather data, benchmarks, and modeling inputs to support feasibility and trial optimization planning.
• Support program review development, including content review and escalation of requirements as needed.
• Plan timelines for validation, deliverable development, stakeholder alignment, presentation preparation, and country validation requests.
• Support validation and Clinical Trials Allocation Committee activities, including scenario planning, risk table inputs, validation review, modeling updates, and final allocation requests.
• Author the initial Global Trials Optimization Report and maintain subsequent report updates throughout the trial lifecycle.
• Complete recruitment needs assessments and ensure trial-level GTO reports remain current and actionable.

Recruitment and Retention Planning

• Lead early recruitment and retention planning during feasibility, including inputs for project cost estimates.
• Develop initial recruitment needs assessments and, where applicable, program-level recruitment budget estimates.
• Submit vendor requests and prepare recruitment and retention plans.
• Partner with legal on concept reviews, vendor proposal reviews, scope of work finalization, and material or tactic reviews.
• Ensure recruitment and retention plans, including enrollment support materials, are implemented effectively.
• Oversee enrollment support material development and tactic execution.
• Provide required materials to the Metrics, Analytics & Performance team to support accurate Study Optimizer plan entry.
• Request and manage appropriate system updates as trial needs evolve.

In-Life Trial Management

• Partner with study teams to identify enrollment challenges, assess risks, and recommend potential mitigations.
• Manage routine enrollment support materials and vendor activities.
• Monitor enrollment performance and prepare standard reporting.
• Analyze performance trends and identify opportunities for enhanced support.
• Coordinate enhanced enrollment support activities, which may include:
  
  • Rescue site and country activities
  • Internal recruitment and retention refresher meetings
  • External recruitment and retention booster meetings
  • Additional participant- or site-facing materials
  • Rescue vendor engagement
  • Advocacy engagement and community outreach

What You'll Bring

Required Qualifications

• Experience supporting clinical trials, feasibility assessments, recruitment planning, enrollment strategy, trial optimization, or related clinical operations activities.
• Strong analytical skills with the ability to collect, interpret, and apply data to support decision-making.
• Experience managing timelines, deliverables, stakeholder reviews, and cross-functional initiatives.
• Ability to collaborate effectively with study teams, vendors, legal partners, analytics groups, and operational stakeholders.
• Excellent written and verbal communication skills, including the ability to develop reports, recommendations, presentations, and strategic plans.
• Strong organizational skills and attention to detail in a fast-paced clinical research environment.
• Ability to manage multiple studies and competing priorities while maintaining quality and accuracy.

Highly Preferred Qualifications

• Experience supporting clinical trials within General Medicine, Dermatology, Rheumatology, Infectious Disease, or Vaccine therapeutic areas.
• Prior experience as a Clinical Research Coordinator, Site Coordinator, Clinical Trial Associate, or similar site-based research role.
• Experience with patient recruitment and retention vendors and enrollment support campaigns.
• Familiarity with patient engagement strategies and patient-centered trial approaches.
• Experience developing patient-facing or site-facing recruitment materials.
• Knowledge of enrollment forecasting, country validation processes, risk assessments, feasibility methodologies, or trial allocation strategies.
• Experience monitoring and analyzing enrollment performance metrics to drive operational improvements.

Why This Role Matters

Successful clinical trials depend on identifying the right sites, reaching the right participants, and adapting quickly when enrollment challenges arise. As a Global Trials Optimization Specialist, you'll play a critical role in helping studies achieve enrollment goals through thoughtful planning, innovative recruitment strategies, and data-driven optimization.

Your contributions will directly support global trial success by:

• Improving study feasibility planning.
• Enhancing patient recruitment and retention outcomes.
• Supporting sites with effective enrollment strategies.
• Providing actionable insights that drive operational decisions.
• Helping bring innovative therapies and vaccines to patients more efficiently.

You'll have the opportunity to collaborate with experienced clinical research professionals across functions and geographies while contributing to meaningful clinical research programs that impact patient lives worldwide.

Candidate Profile

We're especially interested in candidates who bring experience across General Medicine, Dermatology, Rheumatology, Infectious Disease, and Vaccine studies, along with a strong understanding of clinical trial operations, site engagement, enrollment strategy, and recruitment and retention planning.

Successful candidates are:

• Strategic thinkers who use data to drive decisions.
• Strong collaborators who build productive cross-functional relationships.
• Organized project managers who thrive in dynamic environments.
• Problem-solvers who proactively identify enrollment risks and opportunities.
• Passionate clinical research professionals committed to improving trial execution and patient access.

If you're a clinical research professional who enjoys bringing insight, structure, and strategy to global trial enrollment and optimization efforts, we'd love to hear from you. Apply today and help drive the success of meaningful clinical research programs around the world.

Salary range for this role is $95,000-$105,000

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:
$80,600.00 - $145,000.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role.

Summary
Under the direction of a Project Manager Lead supports overall project management of clinical studies by helping control the scope, schedule and cost of assigned project(s), which may range from single service studies to full scope or multiple protocol projects. Duties may include liaising with Customers, vendors and/or investigative sites to manage projects from proposal development to final deliverables to the customer. Upon displaying proficiency, a Project Manager (PM I) may be awarded the opportunity to function at the Project Manager II (PM II) level within a large project team or on a small project which offers continued mentorship.