AstraZeneca

Global Commercial Head, GI ADC

AstraZeneca • $218K — $327K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Master's Degree in a relevant field
  • Significant experience in pharmaceutical/biotechnology leadership
  • Proven track record in strategic marketing and commercialization
  • Expertise in oncology, particularly gastric cancer or GI tumors
  • Strong leadership and team-building capabilities
  • Solid scientific foundation with a focus on cancer therapeutics
  • Highly organized with operational excellence and collaboration skills

Responsibilities

  • Lead commercial strategy and go-to-market plans for multiple gastric cancer indications
  • Drive launch excellence for new cancer therapies in competitive markets
  • Manage global commercial teams and coordinate with regional markets
  • Provide strategic guidance for cross-functional teams and internal stakeholders
  • Represent the global commercial team in executive presentations
  • Serve as a key external representative to collaborators and stakeholders
  • Oversee the Sone-Ve global marketing team and provide matrix leadership across functions

Benefits

  • Continuous learning and development opportunities
  • Diversity-focused work environment
  • Flexible work options balanced with in-office collaboration
  • Supportive culture that values trust and agility
  • Access to a retirement plan and health benefits
Full Job Description
As the Global Commercial Head, GI ADC, you'll play a pivotal role in making a positive impact on changing patients' lives building a new franchise to change the paradigm of care for patients with gastric cancers and other GI tumors.

This role is a key contributor to future growth, across OBU and specifically for our GI Cancer portfolio, we seek dedicated global commercial leadership to launch and enhance the global potential of the brand and seek new opportunities with our R&D colleagues.

The Global Commercial Head, GI ADC, will be accountable for commercial leadership and brand strategy across several indications in early and metastatic gastric cancer including launch readiness, growth and life cycle strategies with new investments across the GI cancer landscape. You will be responsible and accountable for the development and implementation of the brand strategic plan in multiple GI cancer indications including market development, as well as engaging with regions and key markets to drive launch readiness and commercial excellence. You will grow and develop the Sone-Ve global marketing team for current and future in Gastric Cancer and, as appropriate, in other tumor types, as well as provide matrix leadership to colleagues in Medical Affairs, Business Insights, Pricing, Market Access, Diagnostics and Communications.

Who you are:

You are a hard-working leader who is excited about the opportunity to create trust, credibility and value in the long run, in one of the most dynamic and rapidly expanding scientific and commercial areas in healthcare: Oncology.

You can think globally and locally. You can integrate a variety of perspectives into meaningful strategies and programs. You embrace curiosity, collaboration and hard-working risk taking as a prerequisite for joint success. You speak up and challenge, always towards better outcomes and towards highest integrity. You enthusiastically embrace the diversity of individual healthcare ecosystems as significant opportunity. You can relate and connect deeply with various healthcare and business markets in order to deliver direction and support. You can create and mobilize a work environment of highest integrity and quality, fostering learning, growth, individual development and attraction of top talent.

Accountabilities:
  • Accountable for commercial strategy, go to market commercialization and growth strategies for Sone-Ve in multiple gastric cancer indications (as well as potential in other GI cancers)
  • Drive launch excellence for a new NME in a competitive market
  • Lead global commercial team & markets interface; Develop and provide strategic guidance to regions and functions
  • GPT Commercial lead, high degree of influence within GI IBT
  • Lead and represent team for senior leader presentations
  • Be the face of global commercial team for external key collaborators
  • Direct line manager to Sone-Ve global marketing team; matrix leadership for all enabling functions and business partners


The successful leader will bring the following expertise:
  • Customer Alignment: Track record of strong cross-functional collaboration and experience gaining customer alignment to move key initiatives forward.
  • Leadership & Talent Development: Consistent track record of attracting and developing teams with varied strengths and optimizing team performance.
  • Critical Thinking: Experience leading development of cancer/oncology brands, experience working in and/or leading customer facing roles, preferably in the global markets.
  • Strategic Clarity & Messaging: Successful experience in working in the mind of our customers (HCPs, patients, payers); and translating clinical and economic benefits into a compelling message platform.
  • Scientific Skill: Comprehensive understanding of the cancer/oncology space as well as the clinical profile of our brands, oncology and competitor products (current & future) to shape life-cycle planning and management and interact substantially with scientific community and patient advocacy groups.
  • Commercial skill and delivery: Focus on delivering high-impact opportunities at scale by implementing customer-specific approaches. Experience in building as well as shaping markets.
  • Right touch insight: Collaborate with internal customers to drive innovative approaches around building a culture of continuous learning to understand why customers behave as they do and what they value.
  • Develop a Great Place to Work: Able to actively engage, inspire and create follower ship of teams with varied strengths. Engenders trust, empowers team and has courageous conversations. Makes fair, impartial and informed talent decisions. Ability to assess and implement changes to franchise go-to-market model including size & structure of both sales and marketing teams.


Requirements:
  • Master's Degree
  • Strong leadership and team building skills
  • Experienced pharmaceutical/biotechnology executive with significant experience and proven leader with sophisticated general management, strategic marketing, and in-country commercial leadership skills with a solid track record of accomplishment
  • Oncology experience
  • Must have a solid scientific foundation
  • Demonstrates strategic and tactical abilities in developing and efficiently implementing a comprehensive commercial plan
  • Highly organized with a keen sense of what it takes to get the job done; strong operating skills and a sense of urgency with tight-knit collaboration and cross functional partnership


Preferred:
  • Experience in Gastric Cancer or other GI Cancers
  • P&L Management experience
  • Working effectively within a cross functional team
  • MBA / advanced scientific degree


Travel:
  • At least 20% global and domestic travel anticipated


When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca offers an environment where diversity is our strength, reflecting the variety of patients we serve. Here, you'll find a place for continuous learning, exchanging knowledge, and building best practices to grow your career. With a fusion of support, trust, and agility, you'll be encouraged to bring your whole self to work and embrace all the investment, feedback, and ample opportunities on offer. It's an exciting time for our team as we redefine the future of healthcare.

Ready to jump in and be part of something extraordinary? Apply now and take the next step in your career journey with AstraZeneca!

The annual base pay for this position ranges from $218,329 to $327,494. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted
28-Sep-2026

Closing Date
07-Oct-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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