Main Responsibilities and Accountabilities:

GCL Line Manager responsibilities include:

• Providing strategic and tactical medical leadership and guidance for clinical developmentactivities infor 5-8GCPLs

• Works withother GCLsand head of clinical to ensure adequate resourcing across the portfolio

• Manages team ofclinical drug developers, acts as a mentor to physician group in guide clinical developmentexpertisein general and in specific areas of therapeutic knowledge

GCLTALTCDRepresentativeresponsibilitiesinclude:

• Definingtheglobal clinical development strategy for all projects in TA

• Contributing to BD strategy & due diligence for TA &identifiesand evaluates NPOs

• Ensuringhigh quality clinical & scientific content is providedintoRegulatory submissions & ensures defense and negotiation with Regulatory agencies

• Preparingfor stage-gate evaluations and benefitrisk evaluations and assessments

• Overseeingand supports the clinical development activity of assigned Clinical Development reports and works in a matrix with CDT leads and GlobalProjectLeaders toensureoptimalclinical strategy,CDPandprotocol design to supportoptimalProject strategy

GCL Other Responsibilities include:

• Be an active member of the Clinical Development Leadership Team, improving the overall qualityof the group and its deliverables

• Ensuringthat the patient and physician voice is at the forefront in strategy development

• Buildingnetworks with external experts

• Drivingexcellence in clinical development execution

• Partneringwith TA core, extended core & functional partners to ensure scientific & medically robust clinicaldev & med affairs activities

• Enhancingthe reputation of the Company through thought leadership, KOL interactions in fundamental issues affecting the TA

• Representingthe Co & TA externally with KOL, HealthTechnologyand external authorities at key forums

• Ensuring effective presentationsat Scientific andTechnicalReviewCommittee

• Representingthe clinical function on the TALT, responsible for input intoTALTstrategy,overseethe quality of clinical plans in theCVRTA.

Position Qualifications and Experience Requirements:

• MD, Board Certified (or non-USA equivalent) with relevant sub-specialty highly preferred- if not Board Certified in relevant Subspecialty, then experience in that TAisa must.