AstraZeneca

Global Clinical Head

AstraZeneca$331K — $497K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • M.D. or equivalent with 5+ years of drug development experience; specialization in Endocrinology preferred.
  • Deep expertise in late-stage clinical research, specifically in Obesity and/or Type 2 Diabetes Mellitus (DM).
  • Experience delivering multiple complex international studies.
  • Proven track record of influencing stakeholders regionally and globally.
  • Skilled in assessing benefit/risk profiles and creating patient risk management plans.
  • Familiarity with global regulatory submissions and engagement with major regulatory agencies.

Responsibilities

  • Provide scientific strategies for clinical components of Target Product Profile, Target Product Claim, and Clinical Development Plan.
  • Accountable for clinical deliverables within the Clinical Product Team.
  • Oversee overall clinical and scientific content for the assigned asset(s).
  • Collaborate closely with Clinical Operations to implement innovative processes and systems.
  • Prioritize medical activities within the clinical program effectively.
  • Lead clinical studies' design, delivery, and interpretation with a focus on ethical and scientific integrity.

Benefits

  • Qualified retirement programs
  • Paid time off including vacation, holidays, and leaves
  • Health, dental, and vision coverage based on applicable plans
  • Short-term incentive bonuses
  • Equity-based awards for salaried roles
Full Job Description

We are hiring aGlobal Clinical Head (GCH)for Obesity/Diabetesin our Late Cardiovascular, Renal and Metabolism (CVRM)Global Development team. This is a key role where you, with your strong leadership skills and drug development experience, will impact and drive development programs in a dynamic global setting. This role reports to the Vice President, Clinical Metabolismand is based in Boston, MA or Gaithersburg, M.D.

What you99ll do:

The GCH is the most senior medical scientific authority on an asset team and is a core member of the Global Product Team (GPT). The GCH is accountable for all clinical and scientific aspects of the asset(s), including benefit/risk assessment, scientific strategies for clinical components of the Target Product Profile (TPP), Target Product Claim (TPC), Clinical Development Plan (CDP), and core labelling. The GCH develops the project strategy in partnership with the GPL/GPT. The GCH co-leads the Clinical Product Team (CPT) and has accountability for the clinical deliverables.

Accountabilities include:

  • Along with the Global Product Leader, provide scientific strategies for clinical components of the TPP, TPC, CDP, and core labelling
  • Accountable for the clinical parts of CPT deliverables
  • Responsible for overall clinical and scientific content for the asset
  • Work closely with the Clinical Operations lead and ensure the CPT rapidly implements new processes, systems and learning
  • Perform medical prioritization of clinical activities within the clinical program
  • Single-point accountable leader for the design, delivery and interpretation of clinical studies ensuring ethical and scientific integrity in compliance with AZ policies and Good Clinical Practice

Basic Qualifications

  • Graduate of a recognized school of medicine with an M.D. degree or MBBS or equivalent, with 5+ years proven experience in drug development. Specialization in Endocrinology would be preferred.
  • Demonstrated deep late-stage clinical and research expertise in Obesity and/or Type 2 DM
  • Delivered multiple complex and large studies (e.g., including but not limited to international outcome studies).
  • Demonstrated success in influencing global and local cross-functional stakeholders.
  • Experience assessing the benefit/risk profile of an asset and creating patient risk management plans.
  • Experience with global regulatory submissions and interacting with major regulatory agencies.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. Thats why we work, on average, a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

As AstraZeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026.

The annual base pay for this position ranges from $331,874 to $497,810. Our positions offer eligibility for various incentivesan opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

17-Jun-2026

Closing Date

06-Jul-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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