Thermo Fisher Scientific

FSP Senior Scientist - Antibody Engineering

Thermo Fisher Scientific$70K — $91K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree or relevant qualification in molecular biology or biochemistry.
  • 4-6 years of industry experience in a laboratory setting.
  • Strong understanding of antibody structure and function relationships.
  • Proficient in comprehensive protein engineering techniques.
  • Excellent communication and interpersonal skills for data presentation.
  • Proven problem-solving abilities and analytical thinking.

Responsibilities

  • Plan and design experiments, applying technical expertise to meet project deadlines.
  • Optimize yeast display and cell-free protein synthesis protocols for antibody screening.
  • Identify and troubleshoot screening assay issues to maintain quality.
  • Collaborate cross-functionally with automation and biology teams for efficient screening processes.
  • Design and execute secondary screening methods using HTS liquid handlers.
  • Develop strategies for antibody affinity maturation and humanization.
  • Maintain accurate documentation and organized inventory of lab materials.

Benefits

  • A choice of comprehensive national medical, dental, and vision plans.
  • Employee assistance programs and tuition reimbursement options.
  • Generous paid time off including PTO and paid parental leave.
  • Retirement and savings options like a competitive 401(k) plan.
  • Opportunity to participate in an Employee Stock Purchase Plan at a discount.
Full Job Description
Work Schedule
Standard (Mon-Fri)

Environmental Conditions
Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description

As a Senior Scientist, your role will be to conduct advanced diagnostic tests, ensure the highest accuracy and reliability of laboratory data, mentor junior scientists, and drive continuous improvements in laboratory methodologies and quality standards.

What You'll Do:
• Carry out laboratory functions, plan and design experiments and apply technical knowledge and skills to achieve project goals in a precise and timely manner.
• Optimized protocols for yeast display, cell free protein synthesis to achieve better expression and higher sensitivity for antibody screening.
• Identify and troubleshoot critical issues with screening assays, resolving them promptly to ensure consistent progress and quality.
• Collaborate cross-functionally with automation group to coordinate antibody screening and align with biology scientists within company to ensure the antibodies are being tested on time.
• Design and carry out secondary screening strategies using HTS liquid handlers.
• Antibody affinity maturation, optimize humanization and improve antibody developability.
• Keep accurate experimental documentation using Benchling and maintain well-organized inventory of antibodies and antigens.
• Present data in antibody group meetings and project meetings.

Education and Experience:
• Bachelor's degree or equivalent and relevant formal academic / vocational qualification
• Previous experience to provide the knowledge, skills, and abilities to perform the job (comparable to 4-6 years).

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
• Strong background of molecular biology or biochemistry with good GPA.
• Well understanding of antibody structure and function relationships.
• Comprehensive protein engineering techniques.
• Excellent communication skills and interpersonal skills with the ability to present scientific data in team meetings.
• Demonstrated strong problem-solving and analytical thinking skills, showing a proactive attitude towards exploring new approaches.
• Able to collaborate and help other scientists.

Working Conditions and Environment:
• Work is performed in a laboratory and/or a clinical environment with exposure to electrical office equipment.
• Occasional drives to site locations, occasional domestic travel.
• Exposure to biological fluids with potential exposure to infectious organisms.
• Rare exposure to skin and lung irritants, radiation, toxic materials and hazardous waste.
• Personal protective equipment is required such as protective eyewear, garments and gloves.
• Exposure to fluctuating and/or extreme temperatures on rare occasions.

Physical Requirements:
• Ability to work in an upright and /or stationary position for 6-8 hours per day.
• Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment.
• Occasional mobility needed.
• Occasional crouching, stooping, with frequent bending and twisting of upper body and neck.
• Light to moderate lifting and carrying (or otherwise moves) objects including luggage and laptop computer with a maximum lift of 15-20 lbs.
• Ability to access and use a variety of computer software developed both in-house and off-the-shelf.
• Ability to communicate information and ideas so others will understand; with the ability to listen to and understand information and ideas presented through spoken words and sentences.
• Frequently interacts with others to obtain or relate information to diverse groups.
• Works independently with little guidance or reliance on oral or written instructions and plans work schedules to meet goals. Requires multiple periods of intense concentration.
• Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence. Ability to perform under stress. Ability to multi-task.
• Regular and consistent attendance.

Compensation and Benefits
The salary range estimated for this position based in California is $34.00-$44.00.

This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
  • A choice of national medical and dental plans, and a national vision plan, including health incentive programs
  • Employee assistance and family support programs, including commuter benefits and tuition reimbursement
  • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
  • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
  • Employees' Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount


For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

About Thermo Fisher Scientific

Thermo Fisher Scientific Careers

Join the vibrant team at Thermo Fisher Scientific, a global leader in serving science and making the world healthier, cleaner, and safer. With a workforce of over 75,000 professionals, Thermo Fisher Scientific offers unparalleled job opportunities and a culture of innovation that propels your career to new heights. Work You’ll Do At Thermo Fisher Scientific, you will be part of a team that is dedicated to enabling our customers to make the world healthier. Whether you are involved in the development of life-saving drugs or innovative environmental solutions, your work will have a profound impact on society. Our commitment to leadership in the industry is unwavering. With Thermo Fisher Scientific, you will lead projects that set standards in scientific inquiry and market leadership. You will work at the intersection of science, technology, and industry expertise, driving digital innovation in every aspect of our business. Join our diverse team of professionals and engage in roles that span across various functions and disciplines. From research and development to marketing and sales, the breadth of job opportunities available means that you can find the perfect match for your skills and passions. Innovative Work As part of our team, you will have access to cutting-edge tools and technologies that foster creativity and innovation. Thermo Fisher Scientific is home to a dynamic range of career paths, all designed to challenge you and help you grow as a professional. Our employment philosophy emphasizes diversity and inclusivity, ensuring that all team members have the opportunity to thrive. We believe in nurturing talent through robust training programs, leadership development, and opportunities for career advancement. Be Part of a Great Team Working at Thermo Fisher Scientific means being part of a global network of enthusiastic, talented, and ambitious individuals. Our culture is built on collaboration, where each member’s unique skills and perspectives are valued. You will enjoy benefits that support both your professional growth and personal well-being. Future-Proof Your Career Embark on a journey of growth and continuous learning with Thermo Fisher Scientific. We offer a variety of training and development programs that cater to your interests and career goals. From internships for budding scientists to leadership training for aspiring executives, our programs are designed to equip you with the skills needed for a successful and fulfilling career. Explore Discover how our commitment to innovation leads to advancements in health and science: [Read More] Learn about our leadership in environmental sustainability and how you can contribute: [Read More] The Thermo Fisher Scientific Difference Our global presence and commitment to innovation mean that your work extends beyond borders and makes a tangible impact worldwide. The collaboration between our teams drives our leadership in the scientific community and contributes to a culture that embraces diversity and fosters professional growth. Stay Connected Join Our Team Search open positions that match your skills and interest. We are always on the lookout for passionate, curious, and driven team players. Explore our job opportunities and find out how you can contribute to our meaningful work. SEARCH THERMO FISHER SCIENTIFIC JOBS Keep Up to Date Stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. READ CAREERS BLOG Job Alert Emails Customize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding opportunities that await at Thermo Fisher Scientific.
Learn more about Thermo Fisher Scientific
Size
130,000 employees
Market Cap
$213.3 billion
Industry
Net Income
$6.3 billion
Founded
1956
5 Year Trend
+16.5%
Revenue
$32.2 billion
NASDAQ

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