AstraZeneca

Executive Director, Strategy, Oncology R&D

AstraZeneca$270K — $405K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • BA/BS with 10 years or MS/MBA with 8+ years or PhD/MD with 5+ years experience in life sciences, consulting, or equity research.
  • Deep understanding of Oncology Therapeutic Area Strategy with experience in strategic planning and portfolio decisions.
  • Ability to effectively communicate and interact with senior executive teams.
  • Demonstrated leadership and influencing skills in a fast-paced, matrixed environment.
  • Critical and strategic thinking skills with a focus on delivering societal impact.

Responsibilities

  • Own the Oncology R&D portfolio strategy by creating comprehensive therapeutic area strategies.
  • Advise executive senior leadership with insight-driven recommendations on strategic topics.
  • Drive meaningful action by building credibility and trust among stakeholders.
  • Partner across the enterprise to collaborate on long-term strategies that promote innovation.
  • Set high standards for analytical rigor to ensure strategies are evidence-based.
  • Analyze internal and external data to identify trends and translate findings into strategic recommendations.
  • Lead cross-functional collaboration to foster a culture of innovation and accountability.

Benefits

  • Opportunity to impact patients' lives by influencing oncology innovation.
  • Eligibility for short-term incentive bonuses and equity-based awards.
  • Access to qualified retirement programs.
  • Generous paid time off including vacation and holidays.
  • Comprehensive health, dental, and vision coverage.
Full Job Description

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AsanExecutive Director, Strategy, Oncology R&D,you will own and drive the global Oncology R&D strategy,setting priorities for the senior executive team and transforming our approach to deliver impact for patients across disease areas and/or platform technologies aligned to our latest priorities. This is a critical opportunity to apply scientificexpertiseand strategic analysis to influence high‑stakes decisions with direct patient impact. Working at the highest level, you will ensure our choicesoptimizereturn on investment and patient outcomes by presenting clear options, tradeoffs, and recommendations tied to value and risk.

To be successful, you will need:

  • Clear and organized thinking with ability to simplify and prioritize complex problems 
  • The application ofstrong, data-driven analysis to move beyond high-level views

  • Deep scientific acumen to navigate complex data and insights

  • The ability toestablishand maintain credibility with senior audiences

  • Proven track record toanticipateand shapethe oncology market and key trends with emerging science​

Accountabilities: 

  • OwntheOncology R&D portfolio strategy: Lead the creation of comprehensive therapeutic area strategies that integrate clinical, scientific, and commercial insights to shapestrategicpriorities across assets and platforms.

  • Adviseexecutive senior leadership: Provide disciplined, insight driven recommendations on complex strategic topics toseniorstakeholders, delivering clear and actionable guidance on portfolio optimization and investment decisions.

  • Drivemeaningfulaction:Build credibility through expertise, relationships, and trust to persuade and align others without formal authority, leading using robust evidence, metrics, and clear cases to legitimize decisions.

  • Partner across the enterprise: Collaborate with leaders across clinical development, discovery, business development, and other key functions to create cohesive long-term strategies that drive innovation and impact.

  • Analyticaldepth and rigor:Set the standards of strong analytical skills to break down complex problems, ensuring decisions, vision, and strategy are firmly grounded in evidence.

  • Analyze and generate strategic insights:Leadmeticulous analysis of internal and external data toidentifytrends, risks, and opportunities for portfoliogrowth and optimization, translating findings into actionable strategic recommendations.

  • Lead cross-functional collaboration:Build and leada culture of collaboration, innovation, and accountability across all stakeholder groups, partnering with internal and external collaborators to deliver on high-impact strategicobjectives.

  • Dive effective communication: Ensure clear and compelling communication of strategy, progress, and priorities to diverse audiences, both internal and external, maintaining transparency and alignment across the organization.

  • Navigate complex strategic landscapes: Integrate clinical trial design, competitive dynamics, regulatory environments, and market access considerations to advise strategic prioritization and investment decisions.

  • Ensure strategic excellence: Drive clarity and consistency across key strategic processes,establishingbest practices and maintainingthorough standards for analysis, decision-making, and execution.

Essential Skills/Experience: 

  • Education and experience: BA/BS and 10 years of experience with focus in life science programs, consulting, equity research OR MS/MBA and 8+ years of experience OR PhD or MD and 5+ years of experience

  • Oncology expertise: Deep understanding of Oncology Therapeutic Area Strategy which may include a specific disease area and/or platform technologies, with proven experience contributing to strategic planning and portfolio decisions 

  • Executive presence and leadership: Ability to interact and communicate effectively with senior executive teams, with demonstrated ability to lead and influence experienced professionals in a fast-paced, highly matrixed work environment

  • Strategic and impact oriented: Demonstrates critical and creative thinking, anticipates and solves problems with rigorous, fact-based analysis, and thrives in a fast-paced environment, bringing agility and adaptability to deliver outcomes with clear societal impact.  

Preferred Skills/Experience:

  • Deep Scientific Expertise: PhD in life sciences,MD

  • Consulting, VC, equity, or finance experience:Background in management consulting, venture capital, private equity, or finance withdemonstratedability to conduct rigorous financial and strategic analyses to inform investment and portfolio decisionsis strongly preferred

  • Strategic planningexpertise: Experience in strategic planning processes and tools, with ability to translate business needs into coordinated plans and develop creative solutions to complex problems

  • Deep pharmaceutical knowledge: Understanding of pharmaceutical R&D business including clinical trial design, drug development processes, regulatory dynamics, and pricing landscapes in major markets 

  • Consultative leadership: Strong analytical and communication skills combined with effective interpersonal abilities to build trust, influence without authority, and drive alignment across senior cross-functional teams 

  • Financial acumen: Strong financial background and understanding of forecasts, budgets, and financial tools to support strategic decision-making 

  • Global perspective: Ability to work across global teams and priorities delivering operational effectiveness and prioritization in a fast-growing, highly matrixed organization 

Office Working Requirements 

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work atpaceand challenge perceptions. That’swhy we work, on average, a minimum of three days per week from the office. But thatdoesn’tmean we’renot flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. 

The annual base pay for this position ranges from $270,222 to $405,332. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.  

This role offers the opportunity to make a meaningful impact on patients' lives by shaping the future of oncology innovation at AstraZeneca. If you're ready to apply your strategic expertise and leadership to help us achieve our ambitious goals, we encourage you to apply. 

Date Posted

11-May-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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