Internal Job Title: Discovery Postdoctoral Fellow

Position Location: San Diego, CA, USA (Onsite)

* Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.

* This position is not eligible for visa sponsorship. Please only apply if you are currently authorized to work in the US for the 3 year duration of the program.

* This is a full-time training position of up to three years in duration.

Research Opportunity:

The Diseases of Aging and Regenerative Medicine (DARe) department at Novartis investigates how the biology of aging contributes to disease and how these insights can be translated into transformative medicines.  Our mission is to restore cell and tissue function by targeting the fundamental mechanisms that drive age-related decline across multiple disease areas.

We are seeking an exceptional Discovery Postdoctoral Fellow to join DARe in San Diego and develop an independent research project focused on understanding how the aging immune system influences tissue function, regeneration, and disease susceptibility. The fellow will have substantial freedom to shape project direction and build an independent scientific profile through high-impact publications, presentations, and external collaborations. Working alongside experienced mentors and a multidisciplinary network of scientists, the fellow will investigate how age-associated changes in the immune system influence tissue function, repair, and regenerative capacity, and explore approaches to restore regenerative potential in disease-relevant contexts.

Projects may leverage organoid systems, functional genomics, advanced imaging, single-cell profiling, genetic perturbation technologies, and in vivo disease models. Fellows will have access to Novartis' unique cross-disciplinary research ecosystem spanning human genetics, advanced screening, translational research platforms, and expertise across multiple therapeutic areas.

Start Date:

The start date for the 2026 Novartis BR Postdoctoral Fellowship Program cohort is October 2026. Please confirm your availability to meet this date in your cover letter.

Key Responsibilities:

• Design and execute independent, hypothesis-driven research programs aligned with strategic disease biology questions.

• Develop and apply advanced in vitro and in vivo model systems to investigate how age-associated changes in the immune system influence tissue function, repair, and regeneration.

• Design, perform, and interpret molecular, cellular, and in vivo experiments to uncover mechanisms linking aging to tissue dysfunction.

• Develop innovative experimental and analytical approaches to investigate mechanisms of tissue regeneration, aging, and cellular plasticity.

• Communicate scientific findings through publications, internal meetings, and presentations at external scientific conferences.

• Collaborate with multidisciplinary teams spanning regenerative biology, immunology, data science, screening sciences, translational research, and therapeutic area biology.

Essential Requirements:

• PhD (or equivalent doctoral degree) in a relevant scientific discipline completed prior to the fellowship start date. The program is intended for scientists immediately following their PhD training (PhD conferred in 2026 only).

• Strong scientific background in immunology, aging biology, regenerative biology, developmental biology, stem cell biology, cell biology, or related discipline.

• Ability to conduct mechanistic studies to generate, test, and validate biological hypotheses.

• Demonstrated record of scientific achievement (publications, presentations, patents, or equivalent) and ability to independently drive research projects.

• Strong commitment to learning, innovation, and professional development

• Demonstrated hands-on experience in molecular, cellular, and in vivo biology, including cell, organoid, or ex vivo culture; imaging; phenotypic analysis; genetic perturbation approaches; and assay development.

• Ability to work independently and collaboratively in a matrix environment.

Desirable Requirements:

• Experience investigating tissue-immune interactions in the context of aging, regeneration, or disease.

• Experience with animal models, tissue harvesting, and downstream tissue profiling approaches.

How to Apply:

Please submit your CV and cover letter by September 17th, 2026. In your cover letter, please describe your research interests, career aspirations, and how participation in the Novartis Biomedical Research Postdoctoral Fellowship Program will support your long-term development.

Compensation & Benefits:

The starting salary for this position is 87,000 USD per year.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves. #LI-onsite

Salary Range

Skills Desired