AstraZeneca

Director, Theranostics and Radiation Science

AstraZeneca$203K — $305K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • BS in physical sciences or mathematics, plus a graduate degree (M.S. or PhD) in medical physics or related disciplines
  • 5+ years of industry or clinical experience post-residency in medical physics
  • Familiarity with personalized dosimetry for radiopharmaceuticals and experience with programs like Olinda, MIM
  • Strong technical computer skills and understanding of DICOM, PACS, and electronic infrastructure relevant to radiological imaging
  • Experience with radiation-related regulations and guidelines from organizations such as AAPM, SNMMI, and NRC

Responsibilities

  • Optimize and review nuclear medicine imaging protocols and quality control parameters
  • Define requirements for imaging execution at clinical sites and ensure adherence to protocols
  • Design and oversee quality control protocols for imaging review and processing
  • Provide training and mentorship to clinical study teams to meet study objectives
  • Perform patient-specific internal dosimetry calculations
  • Collaborate with the Radiation Sciences team on imaging protocol optimization
  • Support regulatory compliance related to radioactive materials

Benefits

  • 401(k) plan with qualified retirement program
  • Paid vacation and holidays
  • Paid leave and health benefits including medical, dental, and vision coverage
  • Participation in a short-term incentive bonus opportunity
  • Eligibility for equity-based long-term incentive program
Full Job Description

The Director, Theranostics and Radiation Science will play a key role in supporting the management, mentorship, and development of the Radiation Sciences team. You will help guide and support team members,fosteringcollaboration and professional growth within the team.

In addition to leadership, youwill oversee key processes and work cross-functionally with divisions acrossImaging andRadioconjugatedevelopment, including but not limited to Clinical Operations, Preclinical Teams, Pharmacometrics, DMPK, and Regulatory Affairs. The role will also involve working with and helping manage external vendors and contractors to ensure the successful execution of ongoing and upcoming clinical trials.

This position requires ascientific andstrategic mindset, strongtechnical background, and the ability to navigate complex projects while collaborating effectively across internal and external stakeholders.

Responsibilities

  • Optimize and review nuclear medicine imaging protocols, including quality control parameters, image acquisition and reconstruction, radiation dose determination, and protocol dose management.

  • Define requirements and technical support for imaging execution at clinical sites, ensuring proper implementation and adherence to study protocols.

  • Design and oversee quality control protocols, working with both internal teams and external partners for imaging review and processing.

  • Provide training, mentorship, and problem-solving support to internal and external clinical study teams to ensure studyobjectivesare met.

  • Perform image-based, patient-specific dosimetry calculations (internal dosimetry, not external beam radiation therapy [EBRT]).

  • Collaborate with the Radiation Sciences team on imaging protocol optimization, ensuring alignment with best practices in QC, image acquisition, radiation dose management, and compliance with regulatory standards.

  • Support regulatory compliance efforts related to radioactive materials, staying current with guidelines from regulatory and professional organizations (e.g., SNMMI, NRC, and international regulatory bodies).

  • Contribute to research and discovery projects as needed, providing scientific and technicalexpertiseto advance innovation in radiation sciences and molecular imaging.

Basic Qualifications

  • BS degree in physical sciences,mathematicsor other physicalsciencesfollowed by a graduate degree (M.S. or PhD) in medical physics,physicsor related scientific disciplines.

  • Medical physics residency or PostDoctoral trainingwith5+ years ofIndustry and/orclinical experience (post residency).

  • Knowledge and Experience with personalized dosimetry for radiopharmaceuticals, experience with programs such as Olinda, MIM and other imagingand dosimetrypackagesisrequired.

Preferred Qualifications

  • Board certificationispreferred but notrequired.

  • Prior industry experience is preferred but notrequired.

  • Experience with radiopharmaceuticals, Nuclear Medicine,SPECTand PET imaging techniques,reconstruction,and camera quality control proceduresare preferred.

  • Strongconcepts in radiation biology and radiation physics are preferred.

  • Advanced technical computer skills and thorough understanding of modern electronic infrastructures relevant to radiological imaging such as DICOM, PACSisrequiredand, client/server architecturesandimage processingis preferred.

  • Understanding of imaging-related project needs as expressed in a clinical studyprotocol.

  • Experience with radioactive materials regulations or guidelines from regulatory organizations and professional organizations, (e.g.AAPM,SNMMI, NRC, and other country regulatory bodies)

The annual base salary for this position ranges from $203,709-.305,564However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.In addition, our positions offer a short-term incentive bonus opportunity; eligibility toparticipatein our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coveragein accordance withthe terms and conditions of the applicable plans.Additionaldetails of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an 9at-will position9 and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work atpaceand challenge perceptions.That9swhy we work, on average, a minimum of three days per week from the office. But that9doesn9tmeanwe9renot flexible. We balance the expectation of being in the office while respecting individual flexibility.
Join us in our unique and ambitious world.

Date Posted

01-Sept-2026

Closing Date

27-Dec-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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