Pfizer

Director, Portfolio Strategy Inflammation & Immunology

Pfizer$176K — $294K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree with 8+ years of experience; OR Master's degree with 7+ years; OR PhD with 5+ years
  • Experience in pharmaceutical, biotechnology, life sciences, strategy consulting, or related fields
  • Strong strategic and analytical skills to synthesize complex information
  • Experience in supporting portfolio strategy and early commercial assessments
  • Ability to manage multiple priorities in a matrixed environment
  • Strong communication, organization, problem-solving, and stakeholder management skills

Responsibilities

  • Support development of long-range commercial and portfolio strategy for I&I Early Commercial Business
  • Synthesize insights to prioritize strategic trade-offs
  • Assess opportunities for differentiated value creation in the I&I portfolio
  • Translate strategy into clear recommendations for leadership discussions
  • Monitor scientific and competitive landscape for emerging trends and risks
  • Develop early commercial assessments for I&I pipeline assets and opportunities
  • Support commercial input for clinical development and evidence generation

Benefits

  • 401(k) plan with Pfizer Matching Contributions and additional Retirement Savings Contribution
  • Paid vacation, holiday and personal days, and paid caregiver/parental and medical leave
  • Health benefits including medical, prescription drug, dental, and vision coverage
  • Relocation assistance based on business needs and eligibility
  • Hybrid work location arrangement
Full Job Description

What You Will Achieve

The Director, Portfolio Strategy is an individual contributor role within the Inflammation & Immunology (I&I) Early Commercial Business, part of the Global Commercial Strategy organization, reporting to the I&I Portfolio Strategy & Disease Area Lead (7DAL8). This roleis responsible fordeveloping and supporting portfolio strategy, early commercial assessments, and investment decision support across the I&I pipeline. The colleague will bring strong strategic judgment, analytical rigor, and scientific curiosity to help shape portfolio priorities, product concepts, and differentiated commercial opportunities across autoimmune and inflammatory diseases.

The broader I&I and Rare Disease portfoliorepresentssignificant strategic value to realizing Pfizers vision to achieve leadership via breakthroughs in prioritized diseases and biological axes, with the goal of generating highly differentiated, multi-indication mega-blockbusters. Today, the portfolio delivers more than $10B globally, with 22 ongoing clinical studies underway to significantly expand the product portfolio over the next several years. This role will contribute to that ambition by helping shape I&I portfolio strategy and early commercial decision-making across high-value pipeline and lifecycle opportunities.

The Director will partner closely with R&D, Medical Affairs,Global AccessStrategy&Pricing (GASP),BusinessAnalytics& Insights, Competitive Intelligence, Business Development, and US and International Commercial teams to translate scientific, clinical, market, access, and competitive insights into clear portfolio recommendations. This role is focused on early commercial strategy and portfolio decision-making. The Director will help advance disciplined trade-off decisions, long-range portfolio thinking, and AI-enabled ways of working that support patient impact and enterprise value realization for the I&I portfolio.

Responsibilities:

I&I Portfolio Strategy and Long-Range Planning:

  • Support development of long-range commercial and portfolio strategy for the I&I Early Commercial Business, spanning early pipeline assets, lifecycle opportunities, and emerging disease areas.

  • Synthesize scientific, clinical, commercial, access, competitive, and patient insights to inform portfolio priorities and strategic trade-offs.

  • Assess opportunities across near-, mid-, and long-term horizons toidentifyareas of differentiated value creation for Pfizers I&I portfolio.

  • Translate portfolio strategy into clear recommendations, implications, and decision materials for leadership and governance discussions.

  • Monitor shifts in the I&I scientific and competitive landscape toidentifyemerging trends, risks, and potential development opportunities.

Early Commercial Assessment and Product Concept Development:

  • Develop and refine early commercial assessments for I&I pipeline assets, indications, mechanisms, and disease-area opportunities.

  • Support development of product concepts, target product profile input, positioning hypotheses, market archetypes, and commercial opportunity assessments.

  • Translate unmet need, standard of care, competitive dynamics, patient/HCP insights, and access considerations into differentiated commercial hypotheses.

  • Provide commercial input to clinical development, evidence generation, lifecycle, andindicationsequencing discussions in partnership with cross-functional colleagues.

  • Helpidentifykey value drivers, risks, uncertainties, and evidence needs that may influence future launch potential and portfolio value.

Business Development and External Innovation Support:

  • Support commercial assessments of external innovation and Business Development opportunities relevant to the I&I portfolio.

  • Contribute to opportunity assessments,valuationinputs, market-sizing assumptions, competitive scenarios, and strategic fit evaluations.

  • Partner with Business Development, R&D, BAI, GASP, and Competitive Intelligence colleagues to pressure-test assumptions andidentifykey decision points.

  • Develop clear, executive-ready materials that communicate commercialopportunity, strategic rationale, risks, and portfolio implications.

Cross-Functional Partnership and Governance:

  • Partner with the I&I Portfolio Strategy & DAL and cross-functional stakeholders to ensure a strong commercial voice is incorporated into early development and portfolio decisions.

  • Support preparation for governance forums, portfolio reviews, strategy discussions, and investment decision meetings.

  • Build trusted working relationships across R&D, Medical Affairs, GASP, BAI, Competitive Intelligence, Business Development, and Commercial Regions.

  • Influence without direct authority by aligning stakeholders around shared insights, strategic choices, and implications for the I&I portfolio.

AI-Native Ways of Working:

  • Use AI-enabled tools to support scientific and competitive landscape synthesis, market insight generation, scenario development, andstrategyworkstream efficiency.

  • Apply AI-augmented approaches to accelerate analysis,identifypatterns across complex data sources, and improve quality and consistency of strategic outputs.

  • Help embed responsible, compliant AI-enabled ways of working into early commercial strategy, portfolio assessment, and decision-support processes.

  • Stay current on emerging tools and practices that can strengthen commercial strategy development and portfolio decision-making.

Here Is What You Need (Minimum Requirements)

  • Applicant must have a bachelors degree with at least 8 years of experience; OR a masters degree with at least 7 years of experience; OR a PhD with 5+ years of experience

  • Experience in pharmaceutical, biotechnology, life sciences, strategy consulting, corporate strategy, commercial development, business development, forecasting, market research, analytics, or relatedfield.

  • Strong strategic and analytical skills, withabilityto synthesize complex scientific, clinical, market, access, and competitive information into clear recommendations.

  • Experience supporting portfolio strategy, early commercial assessment, business case development, opportunity assessment, or cross-functional strategic planning.

  • Demonstrated ability to manage multiple priorities and deliver high-quality work in a matrixed environment.

  • Strong communication, organization, problem-solving, and stakeholder management skills.

Bonus Points If You Have (Preferred Requirements)

  • Experience in Inflammation & Immunology, autoimmune disease, specialty care, or other complex therapeutic areas preferred.

  • Experience with early commercial strategy, commercial development, portfolio management, corporate strategy, or Business Development assessments.

  • Ability to quickly understand scientific and clinical data and translate implications for commercial opportunity, differentiation, and portfolio value.

  • Experience developing market assessments, product concepts, forecasts, business cases, investment rationales, or strategic options for senior decision-makers.

  • Understanding ofmarket access dynamics, payer considerations, evidence generation, and value demonstration.

  • Comfort working in an AI-native or AI-augmented environment; experience using AI tools to support strategy, synthesis, or analysis is a plus.

  • Ability to thrive in ambiguity, make recommendations with incomplete information, and adapt to evolving portfolio priorities.

  • Discretion, sound judgment, and trustworthiness in handling confidential or sensitive organizational matters.



Work Location Assignment:Hybrid

The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site  U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

About Pfizer

Hospira, Inc. is the provider of injectable drugs and infusion technologies. Through its broad, integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees.

Pfizer Careers

Joining Pfizer’s global team offers more than just job opportunities; it’s a chance to be a part of a company that leads with science and innovates for better health. As a leading biopharmaceutical company, Pfizer is at the forefront of transforming lives through innovation, leadership, and diversity. Work You’ll Do At Pfizer, you will collaborate with some of the brightest minds in the industry, engaging in work that enhances global health and saves lives. Our culture thrives on intellectual curiosity, professional growth, and inclusivity, making every day a learning opportunity. Here, your skills will be honed, your professional acumen will be expanded, and you will be part of a team that values the power of diverse insights to drive success. Pfizer’s Leadership and Growth Lead and innovate with Pfizer, where we value the growth of each employee. Our leadership is committed to providing employees with the training and resources needed to excel in their careers. Pfizer offers a variety of career paths, including roles in research, marketing, finance, technology, and more, each offering a unique blend of challenges and rewards. Internship and Employment Opportunities Start your career with Pfizer through our internship programs or dive straight into a full-time position. We are hiring individuals who are passionate about healthcare and who seek to make a difference in the world. Our internships provide invaluable industry experience, networking opportunities, and a potential pathway to full-time employment. Benefits and Culture Pfizer is dedicated to fostering a workplace where all employees feel valued and can achieve their full potential. We offer competitive benefits packages that support the health, well-being, and financial security of our employees and their families. At Pfizer, you’ll find a culture that encourages collaboration, innovation, and continuous learning. Join Our Team Explore the numerous job opportunities at Pfizer by searching open positions that match your skills and interests. We look for driven, curious, and innovative team players who are ready to advance their careers in a transformative company. Stay Connected Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await at Pfizer. Interview and Resume Tips Prepare for your future with Pfizer by utilizing our resources for resume building and interview preparation. We provide guidance on how to effectively showcase your skills and experiences to align with the needs of a position at Pfizer. Our goal is to help you succeed in securing a role that suits your professional goals and personal growth aspirations. Pfizer: A Place Where You Can Make a Difference Every position at Pfizer contributes to our mission of making the world a healthier place. Whether through direct patient care, research innovation, or corporate roles that support our operations, your work will have global impact. Join us in our journey to change lives—explore Pfizer careers today.
Learn more about Pfizer
Size
79,000 employees
Market Cap
$285.9 billion
Industry
Net Income
$9.6 billion
Founded
1849
5 Year Trend
+9%
Revenue
$41.9 billion
NASDAQ

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