Regeneron Pharmaceuticals, Inc

Director, Portfolio Governance

Regeneron Pharmaceuticals, Inc$183K — $305K *
Pharmaceuticals & Biotech
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree required; advanced degree preferred.
  • 12+ years of experience in biotechnology, pharmaceutical development, or consulting.
  • Deep understanding of drug development lifecycle and portfolio management.
  • Experience designing governance frameworks or decision-making processes.
  • Strong analytical skills to translate data into actionable insights.
  • Exceptional communication and facilitation skills for executive-level engagement.
  • Proven experience in leading and developing high-performance teams.

Responsibilities

  • Own and evolve the governance framework for decision-making.
  • Establish and enforce decision quality and readiness standards.
  • Facilitate governance forums for structured decision-making discussions.
  • Define and manage governance performance metrics for effectiveness.
  • Translate governance feedback into insights for continuous improvement.
  • Synthesize outputs into portfolio-level insights identifying risks and issues.
  • Implement centralized decision documentation for transparency.

Benefits

  • Collaborative and innovative work environment.
  • Opportunity for personal and professional development.
  • Hands-on leadership role with direct people management responsibilities.
  • On-site role to foster relationship-building across teams.
  • Access to technology and digital solutions to improve processes.
Full Job Description

The Director, Portfolio Governance is a strategic leadership role accountable for designing, enabling, and continuously improving the Development governance framework that drives high-quality, timely decision-making across the development portfolio. This role embeds decision excellence, clarity of decision rights, and disciplined execution across the governance forums.
This leader ensures decisions are made at the right level, with the right information, at the right time—enabling portfolio tradeoff decisions, reducing cycle time, and improving decision quality and durability.

This role is a hands-on contributor and people manager responsible to build relationships at all levels of the organization in order to solicit and action stakeholder input regarding the governance framework. This role will navigate the fast-paced and agile environment of Regeneron in a collaborative and innovative manner.

***Please note this role is an onsite opportunity and is not eligible remote.

A typical day in this role looks like:

  • Own and continuously evolve the governance framework to enable effective, scalable decision-making across the portfolio.
  • Establish and enforce decision quality and readiness standards, including clear articulation of options, trade-offs, risks, and recommendations.
  • Where required, facilitate governance forums to ensure structured, decision-focused discussions and clear, actionable outcomes.
  • Define and manage governance performance metrics (e.g., decision cycle time, right-first-time decisions, deferrals, forum utilization) to assess effectiveness.
  • Translate governance metrics and feedback into actionable insights, driving a closed-loop continuous improvement model.
  • Synthesize governance outputs into portfolio-level insights, identifying cross-program risks, recurring issues, and systemic bottlenecks.
  • Establish and maintain centralized decision documentation and knowledge management practices to ensure transparency and traceability.
  • Oversee governance intake, prioritization, and scheduling to ensure alignment to strategic importance, while advancing efficient, scalable processes and leveraging technology to streamline execution.
  • Drive cross-forum integration to streamline escalation pathways, eliminate duplication, and improve decision flow.
  • Partner closely with senior leaders, governance chairs, and stakeholders to align priorities and reinforce governance expectations.
  • Implement governance quality and experience measurement, incorporating multi-directional feedback from teams, executives, and chairs to improve effectiveness.
  • Coach and develop team members ensuring that the organizational strategy delivers the skills, capabilities and processes that enable portfolio delivery are present in his/her team

This role may be for you if you have:

  • Deep understanding of drug development lifecycle and portfolio management.
  • Proven experience designing governance frameworks, operating models, or decision-making processes.
  • Strong analytical skills with ability to translate data into insights and actions.
  • Experience with process improvement methodologies (Lean, Six Sigma) preferred.
  • Exceptional executive communication and facilitation skills.
  • Demonstrated ability to influence senior leadership and drive change in matrixed environments.
  • Strong stakeholder management and cross-functional leadership capabilities.
  • Demonstrate experience leading and developing high-performance teams, including direct people management.
  • Experience leveraging technology and digital solutions to enable scalable processes, improve efficiency and enhance decision-making (e.g. dashboards, workflow tools, analytics platforms).
  • Ability to travel (<10%).


In order to be considered qualified for the this role a minimum of a Bachelor's degree and Minimum 12+ years of experience in biotechnology, pharmaceutical development, or consulting.

Salary Range (annually)

$183,100.00 - $305,200.00

About Regeneron Pharmaceuticals, Inc

Regeneron Pharmaceuticals is a biopharmaceutical company that discovers, develops, and commercializes pharmaceutical products for the treatment of serious medical conditions. The Company has therapeutic candidates in clinical trials for the potential treatment of cancer, eye diseases, and inflammatory diseases, and has preclinical programs in other diseases and disorders. The company’s product portfolio includes EYLEA, an aflibercept injection; ARCALYST, a rilonacept Injection for subcutaneous use; ZALTRAP for metastatic colorectal cancer; trap fusion proteins; and fully human monoclonal antibodies. On March 26, 2012, it was announced that Sanofi and Regeneron are in development with a new cholesterol drug which will help reduce cholesterol up to 72%. Regeneron Pharmaceuticals was founded in 1988 and is currently headquartered in New York, USA.

Regeneron Pharmaceuticals, Inc Careers

Join the innovative team at Regeneron Pharmaceuticals, Inc, a leading biotechnology company renowned for its commitment to science-driven solutions. This is an unparalleled opportunity to advance your career with a company at the forefront of medical breakthroughs and clinical research.

Work You’ll Do

At Regeneron Pharmaceuticals, Inc, you will collaborate with some of the brightest minds in the industry, engaging in work that directly contributes to the health and well-being of populations globally. Our diverse team of professionals is dedicated to pioneering developments in biotechnology through continuous innovation and rigorous research.

Explore Job Opportunities and Growth

Regeneron offers a variety of job opportunities that encourage professional growth and personal achievement. Whether you're seeking an entry-level position or a more senior role, you will find a path that aligns with your career ambitions and skills. Our supportive culture emphasizes leadership development and diversity training, ensuring every team member can thrive.

Internship Programs

Kickstart your career with a Regeneron internship. Our programs provide invaluable industry experience, mentoring from seasoned professionals, and opportunities to develop skills that are crucial in the biotech field. Interns at Regeneron gain hands-on experience, contributing to projects that matter.

Benefits and Culture

Choosing to work at Regeneron Pharmaceuticals, Inc means choosing a career that comes with competitive benefits designed to support you both professionally and personally. We offer comprehensive health benefits, retirement plans, and wellness programs. Our inclusive culture fosters an environment where every employee can flourish, driven by collaboration and mutual respect.

Innovation and Leadership

Lead the way in biotechnological innovation with Regeneron. Our leadership is constantly looking towards the future, investing in cutting-edge technology and research that pave the way for medical advancements. At Regeneron, leadership and innovation go hand in hand, creating a dynamic where breakthroughs are common.

Networking and Professional Development

Enhance your professional network and skill set through Regeneron’s extensive networking opportunities and ongoing professional development programs. We believe in nurturing our talent with advanced training sessions and regular workshops that cover the latest trends and technologies in the biotech industry.

Join Our Team

Discover the impact you can make in a career at Regeneron Pharmaceuticals, Inc. Search for open positions that match your skills and interests. We are continuously hiring and looking for passionate, curious, and innovative team players.

Stay Connected

Keep up to date with the latest at Regeneron by following our careers blog. Gain insights from the experts and learn more about the exciting world of biotech at Regeneron Pharmaceuticals, Inc.

Prepare for Your Interview

Ready to join us? Prepare your resume and refine your interview skills to become part of a company that’s dedicated to changing lives. Personalize your job search and get tailored job alerts directly to your inbox, so you never miss an opportunity to be part of our team. At Regeneron Pharmaceuticals, Inc, your career is poised for tremendous growth and innovation. Explore the opportunities today and be part of a team that’s shaping the future of biotechnology.
Learn more about Regeneron Pharmaceuticals, Inc
Size
10,368 employees
Market Cap
$78.1 billion
Industry
Net Income
$3.5 billion
Founded
1988
5 Year Trend
+27%
Revenue
$8.4 billion
NASDAQ

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