Director, Sustaining Engineering & Lab Operations

Lila Sciences

$168K — $224K *
Pharmaceuticals & Biotech
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • 12-15+ years of lab operations experience in biotech or life sciences environments
  • Proven track record of defining and scaling lab operations systems
  • Deep expertise in CMMS selection, implementation, and governance
  • Experience building and leading teams across multiple functions or sites
  • Experience with ISO 9001:2015 audits related to preventive maintenance and calibration
  • Recognized authority in lab operations, comfortable with senior leadership
  • Strong strategic and systems-level thinking capability.

Responsibilities

  • Define and own the LOMM operating model across Lila sites
  • Establish systems, org structure, and governance for scalable operations
  • Own supply chain continuity for lab consumables and reagents
  • Lead CMMS strategy, implementation, and governance for equipment management
  • Build the Maintenance Management function in collaboration with engineering teams
  • Drive AI integration for operational enhancements in lab management
  • Manage vendor relationships and logistics for lab operations.

Benefits

  • Comprehensive medical, dental, and vision coverage
  • Employer-paid life and disability insurance
  • Flexible time off with generous company holidays
  • Paid parental leave and educational assistance program
  • Commuter benefits including bike share memberships
  • Company-subsidized lunch program.
Full Job Description
Your Impact at LILA

The Director of Sustaining Engineering & LabOps owns that execution layer: fleet reliability, incident response, AISF health, root cause analysis, site-level continuous improvement, and the execution of platform releases and change control at the site - alongside the operational foundation that makes it possible (consumables, reagents, CMMS, asset management, PM, first-response maintenance, multi-shift logistics).

This role will build out Lila's Local Site Sustaining Engineering capability from the ground up, incorporating Maintenance Engineering (ME) as a sub-function. It reports solid-line to the VP, ASP Strategy and Operations with a dotted line to the Director of Sustaining Engineering (Global / Cambridge Core Engineering) for platform standards, change control, and equivalence evidence. The function executes within centrally defined platform constraints and feeds structured signal back to Global Engineering through the operating cadences defined in the ASP Engineering operating model.

You'll define the operating model, lead its expansion to new sites, drive AI-enabled innovation in equipment health and lab operations, and author the standards that travel with every AISF we open. You'll be a principal contributor to the Blueprint program - the global deployment framework defining how Lila builds and runs AISFs at scale.

What You'll Be Building
Local Site Sustaining Engineering (incl. Maintenance Engineering)

The site-level execution layer described in the ASP Engineering operating model - executes within centrally defined platform constraints and feeds structured signal back to Cambridge Core Engineering.
  • Build the Local Site Sustaining Engineering function from scratch in partnership with HCE and Global Engineering; incorporates Maintenance Engineering (instrument PM, calibration, first-response troubleshooting) as a sub-capability
  • Own fleet reliability, incident response, and AISF health at the site - on-call rotations, severity policy, incident playbooks, RCA library
  • Own deployment, commissioning, and operational readiness; partner with the Deployment Project team during stand-up and own steady-state post-handoff
  • Execute the two-lane change model: route platform-critical changes (Lane A) through Global Change Control; manage bounded site-local changes (Lane B) within explicit guardrails; document and time-box emergency-path bypasses
  • Provide the site signature for the dual-signoff go-live model (Platform Release Certification + Site/Workcell Commissioning acceptance)
  • Drive site-level continuous improvement within platform guardrails; surface candidates for promotion into platform releases
  • Triage equipment health data and act on drift signals and re-qualification triggers defined by the Equivalence Review
  • Define escalation and handoff protocols between Sustaining, ME, LabOps, Research Ops, and HCE/Automation
  • Represent the site in standing cadences: Platform Change Control, Release Readiness Review, Fleet Health Review, Equivalence Review
Operating Model & Governance
  • Define and own the operating model across Lila sites - from single-shift pilot to multi-site, continuous operations
  • Establish org structure, staffing model, and governance framework
  • Set and track KPIs (fleet uptime, MTTR, RCA close-out rate, drift response time, inventory accuracy, stockout rate, PM compliance, asset data integrity, ticket resolution); drive structured improvement cycles
Consumables, Reagents & Supply Chain
  • Own end-to-end supply chain continuity for lab consumables, reagents, and PPE across all shifts and sites
  • Govern par-level inventory, reorder triggers, cold storage, and expiry tracking
  • Lead dual-source qualification for high-risk consumables; build the satellite site supply chain playbook for Blueprint
CMMS & Equipment Asset Management
  • Support CMMS implementation and governance; accountable for CMMS data accuracy across commissioned instruments and mobile assets
  • Define asset tagging and location tracking standards aligned with Blueprint's taxonomy
  • Own PM coordination and calibration access; ensure CMMS feeds the broader system-of-record (PLM + release model) maintained by Global Engineering
AI Integration & Continuous Improvement
  • Lead Lila's thinking on AI-enabled site operations and equipment health (predictive maintenance, anomaly detection, AI-assisted RCA, predictive inventory, asset tracking)
  • Bring external best practices from biotech and industrial reliability into Lila's operating model
Vendor & Logistics
  • Own vendor relationships for lab supplies, service contracts, and logistics within approved frameworks; partner with Finance/Corp Dev on contract strategy
  • Oversee lab-side receiving, space readiness for instrument deployments, waste/hazmat scheduling, gas management, and cold storage
  • Manage the support ticket system as the single intake for lab supply, equipment, space, and site engineering requests
Team Leadership
  • Lead, grow, and develop the team across shifts and sites; build the Local Site Sustaining Engineering team from first hire through a fully operational multi-site capability
  • Define staffing models, hiring roadmaps, and capability plans for each sub-function
  • Build a culture of engineering rigor, operational discipline, proactive problem-solving, and continuous improvement
Blueprint & Multi-Site Scaling
  • Author and own the Site Sustaining Engineering and LabOps chapters of Blueprint - processes, system requirements, staffing models, vendor frameworks, sustaining-readiness criteria
  • Pilot the Site Launch Readiness Scorecard for each new facility; feed findings back into Blueprint
  • Partner with the Director of Sustaining Engineering (Global) to keep local execution consistent with platform-level standards and to channel field learnings into platform evolution

What You'll Need to Succeed
  • 12-15+ years of engineering and operations experience with a primary background in sustaining engineering, reliability engineering, or site-level engineering execution for complex hardware-software integrated systems (automation, robotics, semiconductor, aerospace, medical devices, advanced manufacturing, or similar)
  • Demonstrated track record of owning fleet reliability, incident response, and root cause analysis at scale - severity policies, RCA cadences, MTBF/MTTR programs, durable corrective actions
  • Experience operating within (or building) a structured change control model - versioned releases, change boards, traceability of "what's running where" across sites
  • Track record of defining and scaling sustaining or site-level engineering systems - built operating models and governance, not just inherited them
  • Strong operations instincts - engineering rigor only matters if day-to-day execution (supply continuity, asset management, PM, shift coverage) actually works, and you're willing to own that scope directly
  • Experience building and leading teams across multiple functions, shifts, or sites, including hiring from scratch
  • Comfortable in a solid-line / dotted-line accountability structure and partnering with a central engineering authority on standards
  • Recognized authority in your domain; comfortable operating as a peer to VPs and senior leaders
  • Strong strategic and systems-level thinking

Bonus Points For
  • Experience in a biotech or lab-based environment - consumables, reagents, instrument PM, calibration, IQ/OQ/PQ
  • Experience building or overseeing a LabOps or instrument Maintenance Engineering function
  • Experience with equivalence or drift-based qualification frameworks (golden runs, tolerance bands, re-qualification triggers)
  • Experience applying AI or intelligent automation to equipment health and operations workflows
  • Experience supporting multi-shift or 24/7 operations and on-call coverage
  • Familiarity with QMS-adjacent environments (SOP control, change control, training records)
  • Experience contributing to a global site deployment or standardization program
  • Deep expertise in CMMS selection, implementation, and governance

Why This RoleLila is at an inflection point - transitioning from building our first AI Science Factory to operating many, and scientific equivalence across that fleet depends on rigorous site-level engineering execution within tightly defined platform constraints. The Director of Sustaining Engineering & LabOps will be a defining hire in that transition: the engineering leader who builds the site-level reliability foundation, runs the execution layer that keeps the fleet healthy, and ensures every AISF we open runs with the same rigor as the last - while owning the operational scaffolding that makes that execution possible.

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range

$168,000-$224,000 USD

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