Pfizer

Director, Applied AI

Pfizer$176K — $294K *
Enterprise Technology
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • 10+ years in software engineering, AI/ML, or architecture roles with a proven delivery record.
  • Experience building production-grade AI/ML systems or platforms.
  • Hands-on coding ability with expertise in AI/ML, system design, data engineering, or cloud engineering.
  • Proven leadership in managing complex technical projects from inception to completion.
  • Experience leading teams of engineers, contractors, and vendors in production system delivery.
  • Strong ability to link technical choices with business outcomes.
  • Experience in cross-functional and matrixed organizational settings.

Responsibilities

  • Translate strategic AI goals into practical solutions and platforms.
  • Lead technical design and execution of complex initiatives, providing hands-on coding support when necessary.
  • Ensure seamless integration across various platforms, AI models, and business workflows.
  • Direct a delivery team, maintaining high-quality standards and managing dependencies.
  • Challenge incomplete architectures, enforcing quality and performance standards on all solutions.
  • Translate business problems into actionable technical solutions and communicate their commercial value.
  • Provide meaningful technical input into domain-level AI strategy.

Benefits

  • 401(k) plan with matching contributions and retirement savings options.
  • Generous paid time off including vacation, holidays, and personal days.
  • Paid medical leave and family caregiver/parental leave.
  • Comprehensive health benefits including medical, dental, and vision coverage.
  • Eligibility for participation in global performance and long-term incentive plans.
Full Job Description

ROLE SUMMARY

As Director, Applied AI, you lead the realization of AI strategy into tangible, production-grade solutions, platforms, and products. You operate at the intersection of architecture, engineering, and product thinking — translating strategy, patterns, and standards into working systems deployed in real enterprise environments.

You own the end-to-end technical integrity of solutions — from concept through implementation — ensuring they are robust, scalable, and aligned with enterprise architecture and platform capabilities. You connect that build to business outcomes: you understand the commercial problem your work serves, not only the code. And you lead the people who build with you — full-time engineers, contractors, and vendor resources whose day-to-day execution you direct and whose work you review to Pfizer's quality and security bar.

ROLE RESPONSIBILITIES

1)  Solution & Platform Realization  — Translate strategic intent and architectural patterns into working AI solutions and platforms. Own the end-to-end architecture and implementation shape of major solutions, ensuring they are production-ready, scalable, maintainable, and aligned with enterprise architecture.

2)  Technical Leadership & Hands-on Execution  — Lead technical design and execution across complex initiatives as architect, tech lead, and delivery driver. Contribute hands-on code where it accelerates delivery and de-risks execution, and guide teams through design decisions, implementation trade-offs, and integration challenges.

3)  Integration Ownership  — Ensure seamless integration across platforms and services, data systems, AI models, and business workflows — connecting models to real use cases, guardrails to runtime systems, and observability to operational feedback loops within enterprise constraints.

4)  Team & Vendor Leadership  — Lead and coordinate a delivery team of full-time engineers, contractors, and vendor resources. Direct day-to-day technical execution, review their work to Pfizer's quality and security bar, manage dependencies and throughput, and grow the capability of the people you lead.

5)  Technical Quality & Truth Enforcement  — Identify and challenge incomplete or fragile architectures, solutions that are not production-ready, and unrealistic assumptions. Enforce engineering discipline in scalability, observability, performance, and security so solutions meet enterprise quality and reliability standards.

6)  Business & Domain Translation  — Translate business problems into feasible, high-impact technical solutions, and communicate solution direction in terms of business and commercial outcomes. Provide grounded technical input into domain-level AI strategy.

QUALIFICATIONS

Basic Qualifications

  • 10+ years in software engineering, AI/ML, or architecture roles, with a strong delivery track record.
  • Proven experience building production-grade AI/ML systems or platforms.
  • Current hands-on coding ability and strong depth across at least 2–3 of: AI/ML and generative AI; system design / architecture; data engineering; cloud engineering.
  • Demonstrated ability to lead complex technical initiatives end-to-end.
  • Experience leading or coordinating engineers, contractors, and vendors to deliver production systems.
  • Ability to connect technical decisions to business and commercial outcomes.
  • Experience operating in cross-functional, matrixed environments.

Preferred Qualifications

  • Experience with LLMs, retrieval architectures, and AI agents; observability and monitoring; and AI governance and guardrails.
  • Experience with Claude Code, Claude Enterprise, MCP development, and Claude Skill Development
  • Prior role in biopharma TA role, epidemiology, or similar with hands-on real-world data experience
  • Experience in enterprise-scale or regulated environments.
  • Experience leading platform or large solution-development efforts.
  • Familiarity with CI/CD, DevOps, and production operations.

ORGANIZATIONAL RELATIONSHIPS

Senior Director, Applied AI; product management, engineering, architecture, and delivery teams; program leaders; vendor and contractor partners.


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
 

PHYSICAL/MENTAL REQUIREMENTS

Sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis on a computer

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

10-20% travel


Additional Job Information:

Last Date to Apply: June 19, 2026

Work Location Assignment: Hybrid

The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Information & Business Tech

About Pfizer

Hospira, Inc. is the provider of injectable drugs and infusion technologies. Through its broad, integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees.

Pfizer Careers

Joining Pfizer’s global team offers more than just job opportunities; it’s a chance to be a part of a company that leads with science and innovates for better health. As a leading biopharmaceutical company, Pfizer is at the forefront of transforming lives through innovation, leadership, and diversity. Work You’ll Do At Pfizer, you will collaborate with some of the brightest minds in the industry, engaging in work that enhances global health and saves lives. Our culture thrives on intellectual curiosity, professional growth, and inclusivity, making every day a learning opportunity. Here, your skills will be honed, your professional acumen will be expanded, and you will be part of a team that values the power of diverse insights to drive success. Pfizer’s Leadership and Growth Lead and innovate with Pfizer, where we value the growth of each employee. Our leadership is committed to providing employees with the training and resources needed to excel in their careers. Pfizer offers a variety of career paths, including roles in research, marketing, finance, technology, and more, each offering a unique blend of challenges and rewards. Internship and Employment Opportunities Start your career with Pfizer through our internship programs or dive straight into a full-time position. We are hiring individuals who are passionate about healthcare and who seek to make a difference in the world. Our internships provide invaluable industry experience, networking opportunities, and a potential pathway to full-time employment. Benefits and Culture Pfizer is dedicated to fostering a workplace where all employees feel valued and can achieve their full potential. We offer competitive benefits packages that support the health, well-being, and financial security of our employees and their families. At Pfizer, you’ll find a culture that encourages collaboration, innovation, and continuous learning. Join Our Team Explore the numerous job opportunities at Pfizer by searching open positions that match your skills and interests. We look for driven, curious, and innovative team players who are ready to advance their careers in a transformative company. Stay Connected Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await at Pfizer. Interview and Resume Tips Prepare for your future with Pfizer by utilizing our resources for resume building and interview preparation. We provide guidance on how to effectively showcase your skills and experiences to align with the needs of a position at Pfizer. Our goal is to help you succeed in securing a role that suits your professional goals and personal growth aspirations. Pfizer: A Place Where You Can Make a Difference Every position at Pfizer contributes to our mission of making the world a healthier place. Whether through direct patient care, research innovation, or corporate roles that support our operations, your work will have global impact. Join us in our journey to change lives—explore Pfizer careers today.
Learn more about Pfizer
Size
79,000 employees
Market Cap
$285.9 billion
Industry
Net Income
$9.6 billion
Founded
1849
5 Year Trend
+9%
Revenue
$41.9 billion
NASDAQ

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