Alnylam Pharmaceuticals

Cyber Defense Platforms Staff Engineer

Alnylam Pharmaceuticals$174K — $235K *
Information Technology
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • 8+ years in security engineering or operations with ownership of defense platforms
  • Expertise in architecting/administering SIEM, SOAR, EDR, and email security
  • Strong programming skills in Python, Go, or PowerShell for automation
  • Experience managing detection content at scale with MITRE ATT&CK framework
  • Track record of operational improvements through automation
  • Ability to operate autonomously and lead cross-functional efforts
  • Experience with cloud security, particularly AWS-native services
  • Relevant certifications like GIAC or CISSP preferred

Responsibilities

  • Deploy, configure, and manage defense technology stack end-to-end
  • Define and implement the platform roadmap to enhance operational efficiency
  • Engineer and maintain security data pipelines for log onboarding and management
  • Oversee detection content lifecycle including development and testing
  • Implement detection-as-code practices with version control and CI/CD processes
  • Map detection coverage to MITRE ATT&CK and collaborate on enhancement
  • Design SOAR playbooks and automate workflows to streamline incident response
  • Build integrations and APIs linking security platforms and enterprise systems
  • Establish standards for technology deployment and operation in Cyber Defense
  • Lead technical initiatives and mentor team members across the organization

Benefits

  • Comprehensive medical, dental, and vision coverage
  • Life and disability insurance
  • Flexible spending and health savings accounts
  • 401(k) with company match
  • Paid time off, wellness days, and holidays
  • Company-wide recharge breaks
  • Generous family resources and leave programs
Full Job Description
Overview

As the Associate Director (Staff Engineer) for Cyber Defense Platforms, you will own the defense technology stack end-to-end: SIEM, SOAR, EDR, DLP, email security, and anti-phishing platforms, along with the detection content, automation, and tooling that make them effective. This is a senior individual contributor role with enterprise-wide impact: every alert triaged, threat detected, and incident contained across the company depends on the systems you build and operate.

This is a hybrid position and will be primarily based in Cambridge, MA.

Responsibilities

  • Own the deployment, configuration, administration, and lifecycle of defense platforms including SIEM, SOAR, EDR, DLP, email security, and phishing
  • Define the platform roadmap: evaluate, deploy, integrate, and rationalize security technologies to maximize defensive coverage and operational efficiency
  • Engineer and maintain security data pipelines across the enterprise: log source onboarding, normalization, enrichment, retention, and cost management
  • Own the detection content lifecycle end-to-end: development, testing, tuning, versioning, and retirement of rules and analytics across all platforms
  • Establish detection-as-code practices, including version control, peer review, CI/CD deployment, and automated validation of content
  • Map detection coverage to MITRE ATT&CK, identify gaps, and partner with threat intel, IR, and offensive security to convert findings into durable detections
  • Design and build SOAR playbooks and workflow automation that reduce manual analyst effort and accelerate triage and response, including automated handling of user-reported phishing
  • Build internal tooling, integrations, and APIs that connect security platforms to each other and to enterprise systems
  • Set the standards for how Cyber Defense builds, deploys, and operates its technology, and serve as the technical authority for the defense technology domain
  • Lead cross-functional technical initiatives across IT, infrastructure, and engineering teams, and mentor engineers and analysts across the broader team


Qualifications

  • 8+ years of progressive experience in security engineering, security operations, or detection engineering, with demonstrated ownership of defense and security platforms
  • Deep hands-on expertise architecting and administering: SIEM, SOAR, EDR, DLP, or email security and anti-phishing platforms
  • Strong software engineering skills in a language commonly used for security automation (e.g., Python, Go, PowerShell), with experience building production-quality integrations and tooling
  • Proven experience building and managing detection content at scale, measured against frameworks like MITRE ATT&CK
  • Track record of delivering measurable operational improvements through automation, such as reduced response times or expanded capacity without added headcount
  • Ability to operate autonomously in a build-from-zero environment and drive technical work across teams you don't manage
  • Experience standing up or modernizing a security operations stack (SIEM migration, SOAR implementation, EDR rollout) from early maturity
  • Cloud security experience, particularly AWS-native security services
  • Experience in regulated industries (pharma, biotech, healthcare, financial services)
  • Relevant certifications (e.g., GIAC GCDA/GDAT/GCIA, CISSP) or equivalent expertise

#LI-MH1 #LI-Hybrid

U.S. Pay Range

$174,300.00 - $235,700.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

About Alnylam Pharmaceuticals

Alnylam Pharmaceuticals is a biotechnology company that focuses on RNA interference (RNAi) therapeutics. The company's products are designed to silence specific genes that cause diseases. Alnylam's pipeline includes products for the treatment of genetic, cardio-metabolic, and hepatic infectious diseases. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.
Learn more about Alnylam Pharmaceuticals
Size
1,665 employees
Market Cap
$28.7 billion
Industry
Net Income
-$858.2 million
Founded
2002
5 Year Trend
+78.1%
Revenue
$492.8 million
NASDAQ

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