You9ll contribute to our technical approach for evaluating how AI agents reason through biological function: recovering and interpreting experimental evidence to make informed decisions about binding, stability, immune escape, viral fitness, toxin potency, and protein design.
Working with software engineers and biologists, you9ll build ground-truth benchmark datasets (drawn from real discovery and development programs) that rigorously test whether agents can perform the critical quantitative reasoning steps that human scientists execute: parsing noisy assay data, inferring mechanism, and predicting functional outcomes.
Your hands-on expertise in functional biology assays and computational modeling will define how we measure agent capability in understanding and reasoning about biological sequences and structures.
Requirements- Hands-on experience in biochemistry, biophysics, bioengineering, synthetic biology, virology, microbiology, immunology, or a closely related field
- Direct experience generating or analyzing functional-assay data (titration curves, deep mutational scanning, potency assays, cell-based readouts, etc.) OR computational protein design
- Comfort with quantitative modeling applied to noisy experimental data
- Proficiency in Python and/or R for data analysis & visualization
- Familiarity with at least one of:
- Binding affinity & stability (Tite-seq, SPR/BLI, biophysical characterization)
- Immune escape & immunogenicity assessment
- Viral fitness, host-range, or zoonotic spillover evaluation
- Toxin potency or antimicrobial/antiviral resistance
- Protein design or structure-guided functional design
- Gain-of-function or molecular mechanism investigation
Nice-to-Have- Experience designing or troubleshooting functional assays (ELISA, cell-based, biochemical)
- Familiarity with deep learning applied to protein design or functional prediction
- Exposure to regulatory or safety considerations in bioengineering
Compensation & Logistics- OTE 120k - 180k - Performance based pay
- Free meals onsite (lunch and dinner)
- Waterfront office in China Basin, San Francisco
- Full-time, in-person (can be remote)
