Arrowhead Research

Associate Scientist III, CMC Process Development

Arrowhead Research • $78K — $90K *
Verona, WI 53593In-Person
Pharmaceuticals & Biotech
Less than 5 years of experience
Today
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Job Overview by Ladders

Qualifications

  • BS or MS in chemistry or biochemistry
  • 4+ years laboratory experience
  • Proficient in analytical instrumentation and cGMP practices
  • Strong analytical and interpretive skills
  • Excellent communication abilities
  • Strong problem-solving aptitude
  • Eagerness to learn new techniques

Responsibilities

  • Independently deliver analytical results for ongoing projects
  • Perform various analytical techniques like HPLC and LC/MS
  • Analyze and characterize chemicals and pharmaceuticals
  • Interpret experimental data and propose follow-up experiments
  • Calibrate and troubleshoot analytical equipment
  • Collaborate with senior chemists on synthetic approach development
  • Prepare documentation for technology transfer to manufacturing
  • Track project timelines and communicate status updates

Benefits

  • Competitive salary
  • Excellent benefit package
  • Opportunities for professional development
  • Possibility to work on cutting-edge technology
  • Collaborative work environment with experienced chemists
Full Job Description
The Position

The Associate Scientist III in the Process Development Chemistry Group focusing on oligonucleotide analysis and synthesis development. This is an ideal position for an individual with an organic or biological chemistry background who has an interest in projects related to novel technology in synthesis and purification of oligonucleotides and bioconjugates.

Responsibilities
  • Independently provide accurate analytical results in support of new and on-going projects with a focus on process characterization.
  • Perform analytical techniques, such as HPLC, UV/Vis, LC/MS, etc.
  • Handle, analyze and characterize chemicals, pharmaceuticals, and related organic molecules.
  • Analyze data/results and interpret outcome of experiments and independently propose appropriate follow-up.
  • Calibrate, maintain, and troubleshoot all analytical equipment.
  • Work closely with senior chemists on development of new synthetic approaches to desired compounds with an eye toward large-scale synthesis
  • Cooperate with other chemists in the group in preparation of complex organic constructs
  • Analyze small-molecule and macromolecular targets using standard methods
  • Maintain a well-documented laboratory notebook
  • Prepare documentation for transfer of new technologies to the Manufacturing group
  • Track progress against project timelines, generate regular status updates, and communicate progress and issues to management, including presentation of findings at team meetings
  • Coordinate delivery of materials both internally and externally

Requirements
  • BS or MS in chemistry or biochemistry with an excellent understanding of organic and analytical chemistry
  • At least 4 years of experience working in a chemistry laboratory setting
  • Familiar with analytical instrumentation, test methodology/validations, data acquisition systems, and cGMP policies and practices.
  • Ability to correctly analyze data/results and interpret outcome of experiments and to propose appropriate follow-up.
  • Excellent verbal and written communication skills
  • Strong problem-solving skills
  • Eagerness to learn new techniques
  • Experience with small-molecule and macromolecule analytical techniques (e.g., HPLC, UV-Vis spectrophotometry, mass spectrometry, NMR, etc.)

Preferred
  • Masters Degree
  • Minimum of 2 years of experience with HPLC, including troubleshooting.
  • Experience analyzing a variety of in-process samples in support of process characterization studies.
  • Basic familiarity with GLP/GMP regulations


Wisconsin pay range

$78,000-$90,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

About Arrowhead Research

Arrowhead Research is a biotechnology company that develops RNA interference (RNAi) therapeutics. The company was founded in 2007 and is headquartered in Pasadena, California. Arrowhead's RNAi technology targets specific genes to silence their expression, which can be used to treat a variety of diseases. The company's pipeline includes treatments for liver disease, cancer, and cardiovascular disease. Arrowhead has partnerships with pharmaceutical companies such as Amgen and Janssen Pharmaceuticals. The company has received FDA approval for some of its products and is conducting clinical trials for others.
Learn more about Arrowhead Research
Size
329 employees
Market Cap
$4 billion
Industry
Pharmaceuticals & Biotech
Net Income
-$102.6 million
Founded
2004
5 Year Trend
+50.6%
Revenue
$79.8 million
NASDAQ
ARWR
* Ladders Estimates

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