Regeneron Pharmaceuticals, Inc

Associate Manager, Statistical Genetics

Regeneron Pharmaceuticals, Inc$109K — $179K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Human Genetics, Biostatistics, or related field.
  • 0-2+ years of experience; postdoctoral or industry experience preferred.
  • Experience with genome/exome-wide association analysis and rare variant analysis.
  • Proficiency in Python, C/C++, or R for coding.
  • Familiarity with managing large genetic and phenotype data.

Responsibilities

  • Perform genome-scale analyses on genetic data across numerous phenotypes.
  • Collaborate to enhance analytical workflows and implement best practices.
  • Integrate diverse data types to extract insights about human disease.
  • Review and provide input on analysis plans and results for accuracy.
  • Propose solutions to analytical challenges based on critical review.

Benefits

  • Competitive total rewards package including annual bonuses and equity awards.
  • Comprehensive health and wellness programs with insurance benefits.
  • 401(k) company match and pension benefits.
  • Paid time off and family support benefits.
  • Access to fitness centers and wellness initiatives.
Full Job Description

We are looking for a statistical geneticist to contribute to the analysis and interpretation of millions of genotyped and sequenced humans linked with rich phenotype data from around the world. You will leverage these data to gain new insights into disease mechanisms and generate new discoveries that enable Regeneron to create and deliver better medicines to patients in need. Within the broad domain of cardiovascular, metabolic disease, and skeletal diseases, you will work collaboratively with other specialists in genomic data analysis, translational genetics, functional biology, and medicine, to design, execute, and refine analyses that connect genetic variation to human health and disease. You will help develop and implement statistical and computational tools that will allow these analyses to be executed and interpreted at scale. 

A typical day might include the following:

·       Perform genome scale analyses with genotype, imputed, and sequence data from millions of individuals across hundreds of relevant phenotypes and biomarkers. 

·       Work across teams to maintain and improve analytical workflows and implement analytical best practices.

·       Integrate computational tools and diverse molecular data types to generate insights about human disease, interpret results, and prioritize candidate therapeutic targets.

·       Critically review and provide input on analysis plans, results, and summaries to ensure accuracy and reliability. Identify problems and propose solutions or analytical refinements.

 

This role might be for you if you:

·       Have experience in the analysis of large genetic association studies and meta-analysis, including through the analysis of UK Biobank or other biobank-scale data.

·       Have experience in the management of genetic and phenotype data in human genetic studies, including familiarity manipulating sequence data (e.g., VCF files), strategies for genotype imputation, and for quality control of genetic association inputs and outputs.

·       Have demonstrated coding ability in either Python, C/C++, or R. 

·       Enjoy working in a highly interactive environment with a diverse team of colleagues.

·       Employ outstanding communication skills to summarize and present new concepts, methods, and results from human genetic studies to a variety of audiences.

 

To be considered for this role, you must have a PhD in Human Genetics, Biostatistics, or a related field. 0-2+ years experience required; postdoctoral training or relevant industry experience is preferred. The successful candidate should have experience and competence with approaches currently employed in the group, including genome- and exome-wide association analysis, rare variant analysis, Mendelian randomization, LD Score regression, polygenic risk score modeling, meta-analysis, and the use of functional data to prioritize variants and genes of interest. Expertise with cloud computing environments, advanced tools for genomic analyses (PLINK, REGENIE, etc.), and statistical analysis and computation (R, Python, C/C++) are necessary. Experience working in cardiovascular, metabolic, and/or musculoskeletal diseases is preferred. 

Does this sound like you? Apply now to take your first step towards living the Regeneron Way!

 

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 


Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.


For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$109,900.00 - $179,300.00

About Regeneron Pharmaceuticals, Inc

Regeneron Pharmaceuticals is a biopharmaceutical company that discovers, develops, and commercializes pharmaceutical products for the treatment of serious medical conditions. The Company has therapeutic candidates in clinical trials for the potential treatment of cancer, eye diseases, and inflammatory diseases, and has preclinical programs in other diseases and disorders. The company’s product portfolio includes EYLEA, an aflibercept injection; ARCALYST, a rilonacept Injection for subcutaneous use; ZALTRAP for metastatic colorectal cancer; trap fusion proteins; and fully human monoclonal antibodies. On March 26, 2012, it was announced that Sanofi and Regeneron are in development with a new cholesterol drug which will help reduce cholesterol up to 72%. Regeneron Pharmaceuticals was founded in 1988 and is currently headquartered in New York, USA.

Regeneron Pharmaceuticals, Inc Careers

Join the innovative team at Regeneron Pharmaceuticals, Inc, a leading biotechnology company renowned for its commitment to science-driven solutions. This is an unparalleled opportunity to advance your career with a company at the forefront of medical breakthroughs and clinical research.

Work You’ll Do

At Regeneron Pharmaceuticals, Inc, you will collaborate with some of the brightest minds in the industry, engaging in work that directly contributes to the health and well-being of populations globally. Our diverse team of professionals is dedicated to pioneering developments in biotechnology through continuous innovation and rigorous research.

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Choosing to work at Regeneron Pharmaceuticals, Inc means choosing a career that comes with competitive benefits designed to support you both professionally and personally. We offer comprehensive health benefits, retirement plans, and wellness programs. Our inclusive culture fosters an environment where every employee can flourish, driven by collaboration and mutual respect.

Innovation and Leadership

Lead the way in biotechnological innovation with Regeneron. Our leadership is constantly looking towards the future, investing in cutting-edge technology and research that pave the way for medical advancements. At Regeneron, leadership and innovation go hand in hand, creating a dynamic where breakthroughs are common.

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Enhance your professional network and skill set through Regeneron’s extensive networking opportunities and ongoing professional development programs. We believe in nurturing our talent with advanced training sessions and regular workshops that cover the latest trends and technologies in the biotech industry.

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Learn more about Regeneron Pharmaceuticals, Inc
Size
10,368 employees
Market Cap
$78.1 billion
Industry
Net Income
$3.5 billion
Founded
1988
5 Year Trend
+27%
Revenue
$8.4 billion
NASDAQ

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